Sustainable and green catalytic cycloaddition reactions mediated by well-characterized ZnO@PDA-B nanocatalysts for the catalytic conversion of CO<sub>2</sub> to cyclic carbonates. [PDF]
RSC AdvKochan G, Yasar E, Tumbul A, Kilic A.
europepmc +1 more source
Highly Enantio- and Diastereoselective Synthesis of Tetrahydrofuran Frameworks via Chiral Lewis Acid-Catalyzed Formal [3+2] Cycloaddition of Allylsilanes. [PDF]
Angew Chem Int Ed EnglLee H +5 more
europepmc +1 more source
Biocatalysts for Peptide Geranylation With Linear and Cyclic Prenyl Groups
Angewandte Chemie International Edition, EarlyView.A combination of genome mining, synthetic biology, and biocatalytic assays revealed enzymes that install linear and cyclized prenyl moieties on ribosomally or chemically synthesized peptides. The promiscuity of both enzymes, while being specific for modification of C‐terminal tryptophans, enables enzymatic access to peptide terpenoid hybrids.
Sarolt Magyari +10 more
wiley +1 more source
Harnessing Photons for Trifold Output: Chromic, Luminescent, and Mechanical Transformations in a Smart Material. [PDF]
Angew Chem Int Ed EnglXin L, Chen YR, Pan JQ, Tan B, Zhang J.
europepmc +1 more source
Accelerating green heterocyclic synthesis: Convergence of AI, automation, and sustainable chemistry
Bulletin of the Korean Chemical Society, EarlyView.Green heterocyclic synthesis and data‐driven tools such as AI, high‐throughput experimentation, continuous flow, and self‐driving laboratories have developed largely in parallel. This review connects them and asks how green metrics such as E‐factor and PMI might serve as explicit optimization targets rather than post‐hoc measures, toward sustainable ...
Noor Aisyah Ahmad Shah +8 more
wiley +1 more source
Substrate-Controlled Dearomative Cycloadditions of Perfluoronaphthalenes via Visible-Light Energy Transfer Catalysis: Switchable Access to [2+2], [4+2], and Diastereoconvergent Cycloadducts. [PDF]
Angew Chem Int Ed EnglJana SK +6 more
europepmc +1 more source
Bulletin of the Korean Chemical Society, EarlyView.Abstract DNA‐encoded libraries (DELs) enable large‐scale screening for hit identification, but accessing sp3‐rich, three‐dimensional chemotypes beyond flat, aromatic scaffolds remains challenging. Multicomponent reactions (MCRs) assemble such complexity from simple building blocks in a single step, and reaction‐engineering strategies have extended on ...
Jimin Moon +3 more
wiley +1 more source
Biomimetic N‐cyano sulfoximine–thiazole ligation for antibody–drug conjugate assembly
Bulletin of the Korean Chemical Society, EarlyView.Biomimetic N‐cyano sulfoximine–thiazole ligation is applied for the first time to antibody–drug conjugate assembly. Installation of a sulfoximine handle on trastuzumab followed by ligation with a cysteine‐functionalized payload affords model ADCs with tunable drug‐to‐antibody ratios of 2–8 under mild aqueous conditions.
Eunsil Kim +7 more
wiley +1 more source
Three-site cycloadditions within one reaction intermediate with site-selectivity controlled by electronic and size bias. [PDF]
Nat CommunMaitra C +6 more
europepmc +1 more source