Results 51 to 60 of about 140,419 (292)

A Review of the Synthetic Strategies toward Dihydropyrrolo[1,2-a]Pyrazinones

Organics, 2021
Dihydropyrrolo[1,2-a]pyrazinone rings are a class of heterocycles present in a wide range of bioactive natural products and analogues thereof. As a direct result of their bioactivity, the synthesis of this privileged class of compounds has been ...
Pieterjan Winant, Tomas Horsten, Shaiani Maria Gil de Melo, Flavio Emery, Wim Dehaen   +4 more
doaj   +1 more source

Synthesis of 5,6-Dihydropyrazolo[5,1-a]isoquinolines through Tandem Reaction of C,N-Cyclic Azomethine Imines with α,β-Unsaturated Ketones

Molecules, 2023
An innovative and efficient approach has been developed for the synthesis of 5,6-dihydropyrazolo[5,1-a]isoquinolines. This one-pot tandem reaction involves the reaction of C,N-cyclic azomethine imines with α,β-unsaturated ketones, using K2CO3 as the base
Young Jae Yun, Sung-Gon Kim
doaj   +1 more source

Concerted [4 + 2] and Stepwise (2 + 2) Cycloadditions of Tetrafluoroethylene with Butadiene: DFT and DLPNO-UCCSD(T) Explorations. [PDF]

, 2020
Tetrafluoroethylene and butadiene form the 2 + 2 cycloadduct under kinetic control, but the Diels-Alder cycloadduct is formed under thermodynamic control. Borden and Getty showed that the preference for 2 + 2 cycloaddition is due to the necessity for syn-
Houk, KN, Liu, Peng, Mackey, Joel L, Pemberton, Ryan P, Svatunek, Dennis   +4 more
core  

A Stepwise [4 + 3] Cycloaddition Reaction of the 1,3-Diphenyl-2-azaallyl Anion [PDF]

, 1993
The 1,3-diphenyl-2-azaallyl anion (1) undergoes [3 + 2] cycloaddition reactions with the s-cis-fixed 1,3-dienes 8-11. In contrast, 1,1,2,2,3,3-hexamethyl-4,5-bis(methylene)cyclopentane (7) reacts with 1 to give the [4 + 3] cycloadduct 13 and the linear 1,
Anh, Baran, Baran, Baran, Baran, Baran, Blomquist, Boche, Boche, Bower, Eidenschink, Fleming, Huisgen, Juday, Kauffmann, Kauffmann, Kaufmann, Mayr, Mayr, Mayr, Mayr, van Straten, Wilcox, Woodward   +23 more
core   +1 more source

Catalytic [4+2]- and [4+4]-cycloaddition using furan-fused cyclobutanone as a privileged C4 synthon

Nature Communications
Cycloaddition reactions play a pivotal role in synthetic chemistry for the direct assembly of cyclic architectures. However, hurdles remain for extending the C4 synthon to construct diverse heterocycles via programmable [4+n]-cycloaddition.
Kemiao Hong, Mengting Liu, Lixin Qian, Ming Bao, Gang Chen, Xinyu Jiang, Jingjing Huang, Xinfang Xu   +7 more
doaj   +1 more source

Exploring Pyrrolo-Fused Heterocycles as Promising Anticancer Agents: An Integrated Synthetic, Biological, and Computational Approach

Pharmaceuticals, 2023
Five new series of pyrrolo-fused heterocycles were designed through a scaffold hybridization strategy as analogs of the well-known microtubule inhibitor phenstatin.
Roxana-Maria Amărandi, Maria-Cristina Al-Matarneh, Lăcrămioara Popovici, Catalina Ionica Ciobanu, Andrei Neamțu, Ionel I. Mangalagiu, Ramona Danac   +6 more
doaj   +1 more source

Stable Radical Polymers as New Electroactive Materials: Synthesis, Properties, and Emerging Applications

Advanced Functional Materials, EarlyView.
This review covers the recent advances in the synthesis and properties of stable radical polymers (SRPs) and presents their applications in electronics, magnetics, optoelectronics, and biomedicines. The review concludes with a discussion of the challenges in radical chemistry and functionalization, while shedding light on the groundbreaking potential ...
Yufeng Xiong, Yingjiang Li, Xinfang Cui, Shiwei Li, Xiangdong Peng, Yanyun Ju, Tong Zhou, Rui Feng, Yang Zhang, Zehong Wang, Qing Wang, Lijie Dong   +11 more
wiley   +1 more source

Catalysis in Click Chemistry Reactions Controlled by Cavity Quantum Vacuum Fluctuations: The Case of endo/exo Diels-Alder Reaction [PDF]

arXiv, 2022
Achieving control over chemical reaction's rate and stereoselectivity realizes one of the Holy Grails in chemistry that can revolutionize chemical and pharmaceutical industries. Strong light-matter interaction in optical or nanoplasmonic cavities might provide the knob to reach such control.
arxiv  

A multiconfigurational hybrid density-functional theory [PDF]

Journal of Chemical Physics 137, 4 (2012) 044104, 2012
We propose a multiconfigurational hybrid density-functional theory which rigorously combines a multiconfiguration self-consistent-field calculation with a density-functional approximation based on a linear decomposition of the electron-electron interaction.
arxiv   +1 more source

Syntheses and crystal structures of [IrIII{C(CHCO2Et)(dppm)2-κ4P,C,C′,P′}ClH]Cl·2.75CH2Cl2 and its derivatives, [IrIII{C(CHCO2Et)(dppm)2-κ4P,C,C′,P′}(CH2CO2Et)Cl]Cl·CH3OH·0.5H2O, [IrIII{C(CHCO2Et)(dppm)2-κ4P,C,C′,P′}Cl2]Cl·CH3OH·2H2O and [IrIII{C(CHCO2Et)(dppm)2-κ4P,C,C′,P′}(CH2CO2Et)(CO)]Cl2·2CH2Cl2·1.5H2O

Acta Crystallographica Section E: Crystallographic Communications, 2019
The common feature of the four iridium(III) salt complexes, (bis{[(diphenylphosphanyl)methyl]diphenylphosphanylidene}(ethoxyoxoethanylidene)methane-κ4P,C,C′,P′)chloridohydridoiridium(III) chloride methylene chloride 2.75-solvate (4), (bis ...
Inge Schlapp-Hackl, Christoph Falschlunger, Kathrin Zauner, Walter Schuh, Holger Kopacka, Klaus Wurst, Paul Peringer   +6 more
doaj   +1 more source