Results 81 to 90 of about 216,387 (290)
Angewandte Chemie, 2017 A metal-free [2+2] cycloaddition and 1,4-addition sequence induced by S-centered radicals has been achieved by treating benzene-linked allene-ynes with aryldiazonium tetrafluoroborates and DABCO-bis(sulfur dioxide) in a one-pot procedure.
Feng Liu +6 more
semanticscholar +1 more source
Regioselective and stoichiometrically controlled conjugation of photodynamic sensitizers to a HER2 targeting antibody fragment [PDF]
, 2014 The rapidly increasing interest in the synthesis of antibody–drug conjugates as powerful targeted anticancer agents demonstrates the growing appreciation of the power of antibodies and antibody fragments as highly selective targeting moieties.
Boyle, Ross W. +6 more
core +1 more source
Formal [3+2] Cycloaddition Reactions of Electron-Rich Aryl Epoxides with Alkenes under Lewis Acid Catalysis Affording Tetrasubstituted Tetrahydrofurans [PDF]
, 2020 We report on the regio- and stereoselective synthesis of tetrahydrofurans by reaction between epoxides and alkenes in the presence of a Lewis acid. This is an unprecedented formal [3+2] cycloaddition reaction between an epoxide and an alkene.
Cuca-Suárez, Luís +3 more
core +1 more source
An intramolecular cycloaddition
Tetrahedron Letters, 1977 Tetrahedron Letters 18 (1977) 3437-3440. doi:10.1016/S0040-4039(01)83260-3 ; Received by publisher: 1977-06-20 ; Harvest Date: 2016-01-04 12:20:50 ; DOI:10.1016/S0040-4039(01)83260-3 ; Page Range: 3437 ...
Department of Chemistry, University of Florida, Gainesville, Florida 32611 U.S.A. ( host institution ) +3 more
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Journal of the American Chemical Society, 2018 We report a stereoselective formal [3 + 2] cycloaddition of cyclopropyl ketones and radical-acceptor alkenes to form polysubstituted cyclopentane derivatives.
Wei Hao +4 more
semanticscholar +1 more source
Computational study of a model system of enzyme-mediated [4+2] cycloaddition reaction. [PDF]
PLoS ONE, 2015 A possible mechanistic pathway related to an enzyme-catalyzed [4+2] cycloaddition reaction was studied by theoretical calculations at density functional (B3LYP, O3LYP, M062X) and semiempirical levels (PM6-DH2, PM6) performed on a model system.
Evgeniy G Gordeev, Valentine P Ananikov
doaj +1 more source
Nature Communications, 2022 There is great interest in methods for catalytic enantioselective construction of axially chiral compounds found in natural products. Here, the authors develop a cycloaddition strategy for atroposelective construction of indole-based biaryls via chiral ...
Hui Yang +8 more
doaj +1 more source
Regioselective reactions of 3,4-pyridynes enabled by the aryne distortion model. [PDF]
, 2013 The pyridine heterocycle continues to play a vital role in the development of human medicines. More than 100 currently marketed drugs contain this privileged unit, which remains highly sought after synthetically. We report an efficient means to access di-
Garg, Neil K, Goetz, Adam E
core
Enantioselective cycloaddition reactions
ChemInform, 1991 Publisher Summary This chapter reviews the cycloadditions reactions because they are popular, widely used, and also constitutes enormous body of chemistry. The chapter focuses on the landmark achievements as well as state-of-the-art examples of relevant chemistry.
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Cycloaddition Reactions of Heterophospholes
ChemInform, 2004 AbstractFor Abstract see ChemInform Abstract in Full Text.
Raj K. Bansal +2 more
openaire +3 more sources