Results 51 to 60 of about 73,410 (278)

Diels‐Alder Click Chemistry as a Dynamic‐Covalent Crosslinking Method in Spheroid‐Encapsulating Hydrogels for Cartilage Engineering

open access: yesAdvanced Healthcare Materials, EarlyView.
This research shows the development of hydrogels with Diels‐Alder click chemistry for engineering cartilage‐like tissue. The hydrogels support cartilage spheroids which could be cultured for at least 28 days. Furthermore, the spheroids showed a tendency to fuse together into a more consistent construct, and produced important components needed for ...
Sanne M. van de Looij   +8 more
wiley   +1 more source

Synthesis and use of a stable aminal derived from TsDPEN in asymmetric organocatalysis [PDF]

open access: yes, 2010
A stable aminal formed stereoselectively from (R,R)-N-tosyl-1,2-diphenyl-1,2-ethylenediamine (TsDPEN) is capable of asymmetric organocatalysis of Diels-Alder and alpha-amination reactions of ...
Clarkson, Guy J.   +3 more
core   +1 more source

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

open access: yesAdvanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best   +5 more
wiley   +1 more source

Airborne 1O2 Delivery via a Superhydrophobic Dressing as a Pathway to Next‐Generation Wound Therapies, an in Vivo Murine Burn Model Study

open access: yesAdvanced Healthcare Materials, EarlyView.
Schematic illustration of the SH bandage placed on an infected burn wound and its role in wound healing. A superhydrophobic PDMS membrane coated with the PS verteporfin is placed over the wound area and illuminated with a red laser at 690 nm, generating airborne 1O2 above the tissue.
Fernanda Viana Cabral   +8 more
wiley   +1 more source

Preparation of 4 '-spirocyclobutyl nucleoside analogues as novel and versatile adenosine scaffolds

open access: yes, 2019
Despite the large variety of modified nucleosides that have been reported, the preparation of constrained 4 '-spirocyclic adenosine analogues has received very little attention.
De Vleeschouwer, Freija   +10 more
core   +1 more source

Controlling thermal reactivity with different colors of light [PDF]

open access: yes, 2017
The ability to switch between thermally and photochemically activated reaction channels with an external stimulus constitutes a key frontier within the realm of chemical reaction control.
Barner-Kowollik, Christopher   +2 more
core   +4 more sources

Azaporphyrinoid‐Based Photo‐ and Electroactive Architectures for Advanced Functional Materials

open access: yesAdvanced Materials, EarlyView.
A long‐standing collaboration between the Torres and Guldi groups has yielded diverse azaporphyrinoid‐based donor‐acceptor nanohybrids with promising applications in solar energy conversion. This conspectus highlights key molecular platforms and structure‐function relationships that govern light and charge management, supporting the rational design of ...
Jorge Labella   +3 more
wiley   +1 more source

Azetidinylideneketenimines as a Multimodal Synthetic Platform: Coordination Chemistry and Cycloaddition‐Triggered Transformations

open access: yesAngewandte Chemie, EarlyView.
Cross‐coupling/homologation sequence between a stable three‐membered‐ring carbene and isocyanides enables facile and rapid access to novel methyleneketenimines and the first bis(methyleneketenimine). Reactivity studies gave rise to the first methyleneketenimine‐transition metal complexes, unique multimodal reactivity ranging from CO2, isocyanate ...
Taichi Koike   +3 more
wiley   +2 more sources

Dimerization of propargyl and homopropargyl 6-azido-6-deoxy-glycosides upon 1,3-dipolar cycloaddition

open access: yesBeilstein Journal of Organic Chemistry, 2008
Copper-catalyzed, thermal or microwave promoted 1,3-dipolar cycloaddition (Click Reaction) of 2-propynyl and 3-butynyl 2,3,4-tri-O-acetyl-6-azido-6-deoxy-glycopyranosides in the D-gluco, D-galacto and D-manno series afford the corresponding dimeric ...
Nikolas Pietrzik   +2 more
doaj   +1 more source

Ferrocene-derived P,N ligands : synthesis and application in enantioselective catalysis [PDF]

open access: yes, 2013
Due to their unique steric and electronic properties, air-stability and modular structure, chiral hybrid P,N-ferrocenyl ligands play a prominent role in the field of asymmetric catalysis.
Noël, Timothy, Van der Eycken, Johan
core   +1 more source

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