Results 71 to 80 of about 2,936 (205)
, 2016 A new synthesis of 2-alkoxy-1,1-cyclobutane diesters and their first use in dipolar cycloadditions is reported. Both the formation of the donor−acceptor cyclobutanes and their subsequent annulation with in situ formed imines are catalyzed by Yb(OTf)3 ...
Mahmoud M. Abd Rabo Moustafa (2130100) +1 more
core +1 more source
Beilstein Journal of Organic ChemistryBimanes, a class of molecules based on the 1H,7H-pyrazolo[1,2-a]pyrazole-1,7-dione scaffold, were first introduced by E. M. Kosower in 1978. In this study, we report the topochemical cycloaddition of diethyl 2,6-dichloro-1,7-dioxo-1H,7H-pyrazolo[1,2-a ...
Metodej Dvoracek +3 more
doaj +1 more source
ChemistryEurope, Volume 4, Issue 6, June 2026.Polycyclic intermediates enable stereocontrolled synthesis of densely functionalized cis‐1,3‐diamine and amino alcohol carbocycles and heterocycles via structural‐to‐functional complexity transformations from low‐complexity starting material. Cis‐1,3‐functionalized carbocycles and saturated heterocycles are ubiquitous motifs in natural products ...
Jiayi Zhu +2 more
wiley +1 more source
New Strategies for Stereoselective Preparation of Densely Functionalized Cyclobutanes:
, 2022 Thesis advisor: Shih-Yuan LiuThis dissertation describes the utility of 1,2-azaborine motif as a 4C+1B+1N synthon in organic synthesis, especially for the preparation of densely functionalized cyclobutanes based on the framework of the 1,2-azaborine ...
Yang, Xinyu
core
, 2023 Ring-opening of bicyclo[1.1.0]butanes (BCBs) is emerging as a powerful strategy for 1,3-difunctionalized cyclobutanes synthesis. However, the reported radical strain-release reactions are typically plagued with diastereoselectivity issues.
Yuanjiu, Xiao +8 more
core +1 more source
Nature CommunicationsPhotoinduced dearomatization of arenes is a powerful strategy in organic synthesis to disrupt the stable aromaticity; however, the asymmetric dearomatization photocatalysis of unactivated arenes remains highly challenging and rare.
Jie Yang +7 more
doaj +1 more source
ChemPhotoChem, Volume 10, Issue 6, June 2026.This review surveys the literature on light‐driven dearomative [2+2] cycloadditions of indoles, highlighting their power to access complex cyclobuta[b]indole frameworks. Advances in photocatalysis, sensitizer design, and reaction engineering enable selective and sustainable assembly of strained three‐dimensional architectures, expanding opportunities ...
Maria Chiara Cabua +4 more
wiley +1 more source
Mechanochemistry of cyclobutanes
Science China ChemistryAbstractThe field of polymer mechanochemistry has been revolutionized by implementing force-responsive functional groups—mechanophores. The rational design of mechanophores enables the controlled use of force to achieve constructive molecular reactivity and material responses.
Roberto Obregon, Junpeng Wang
openaire +1 more source
, 1995 Enantiomerically enriched (+)-grandisol and (+)-fraganol were synthesized using as the key step a new stereoselective synthesis of cyclobutanes fused to γ-lactones by a stereochemically-controlled intramolecular alkylation of α-benzenesulfonyl-γ-lactones.
Rodríguez, Carmen M. +2 more
core +1 more source
The Role of N6‐Methyladenosine Modification in Health and Disease
MedComm, Volume 7, Issue 6, June 2026.N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li +6 more
wiley +1 more source