Results 61 to 70 of about 2,936 (205)
, 2019 The emergence of new methods for the stereoselective synthesis of strained carbocycles is a challenging but worthwhile endeavour. Cyclobutanes, in particular, have attracted the attention of both medicinal chemists and material scientists for their ...
Colomer, I +3 more
core +1 more source
RAD51 and RAD51 paralog inhibition sensitizes nonreplicating quiescent keratinocytes to UV radiation
Photochemistry and Photobiology, EarlyView.UV radiation and other compounds generate DNA adducts that block transcription and induce cell death if not removed by the nucleotide excision repair system. In this work, we used a small‐scale pharmacological screen to discover that inhibition of the recombinase RAD51 sensitized nonreplicating quiescent keratinocytes to both UVR and other agents that ...
Saman Khan +3 more
wiley +1 more source
Photoprotective potential of gadusol against ultraviolet B radiation in melanocytes
Photochemistry and Photobiology, EarlyView.Gadusol protects melanocytes from ultraviolet B (UVB)‐induced damage without cytotoxicity. Abstract The increasing incidence of skin cancer, including melanoma, combined with the need for ultraviolet (UV) filters that are safe for human health and marine ecosystems, is driving the search for new photoprotective agents.
Andressa Mai Matsumoto +8 more
wiley +1 more source
Depth of DNA photodamage in human corneas exposed to 222 nm or 254 nm UV
Photochemistry and Photobiology, EarlyView.Representative confocal 3D image of a section of a human cornea showing nuclei in blue (Hoechst 33342) and green, which was assigned to cells exhibiting Alexa555 conjugated to anti‐CPD antibody. The depth of photodamage was measured in Z‐stacks of the human corneal epithelium after exposure of the anterior surface to 50 or 100 mJ/cm2 at 222 or 254 nm ...
Manuela Buonanno +6 more
wiley +1 more source
Photochemistry and Photobiology, EarlyView.Scaffold hopping strategy used to develop chalcones structure‐related to the avobenzone tautomer. Positive aspects of 2‐hydroxychalcones are highlighted. Abstract Chalcones are α,β‐unsaturated ketones with extended π‐conjugation, making them promising scaffolds for the development of organic UV filters.
Gabriela Zanella Marcon +11 more
wiley +1 more source
Veterinary Ophthalmology, Volume 29, Issue 4, July 2026.ABSTRACT Purpose Assess in vitro efficacy of a device emitting 265 nm UVC light against bacteria isolated from veterinary infectious keratitis. Methods Twenty‐seven clinically‐derived bacterial isolates: Staphylococcus pseudintermedius (n = 10; including n = 2 methicillin‐resistant Staphylococcus pseudintermedius [MRSP]), Staphylococcus aureus (n = 1),
Oliver Joe Williams +3 more
wiley +1 more source
Synthesis of 1,3-Substituted Cyclobutanes by Allenoate-Alkene [2 + 2] Cycloaddition
, 2016 A method for the [2 + 2] cycloaddition of terminal alkenes with allenoates is presented. This process allows for the rapid synthesis of 1,3-substituted cyclobutanes in high yield under simple and robust reaction ...
M. Kevin Brown (1407304) +1 more
core +1 more source
Photolyzable Polymer Brushes: Subtractive 3D Structuring of Surfaces Using Water and Light
Angewandte Chemie, Volume 138, Issue 22, 25 May 2026.Facile structuring of polymer brushes is achieved by flipping the process from controlled growth to controlled brush photolysis. Using surface‐initiated radical ring‐opening polymerization of cyclic monomers with photocleavable cyclobutane rings, photodegradable targets are embedded into the polymer chains. The enabled continuous subtractive patterning
Henrik Kalmer +11 more
wiley +2 more sources
1,1‐and 1,2‐Diborylalkenes: Preparation and Synthetic Applications
Advanced Synthesis &Catalysis, Volume 368, Issue 12, 17 June 2026.In this review, we highlight recent advances in the synthesis and reactivity of 1,1‐diborylalkenes and 1,2‐diborylalkenes, along with various transformations leading to C‐C, C‐heteroatom, and multicomponent products. By providing a comprehensive and practical resource, this review aims to assist researchers in exploring the synthetic utility of 1,1 and
Jayaram Vankudoth +2 more
wiley +1 more source
Analytical Science Advances, Volume 7, Issue 1, June 2026.ABSTRACT This study investigated the prevalence of electronic smoking device (ESD) use and its associated behavioural and chemical risks among university students in Bahia, Brazil. A cross‐sectional survey was conducted with 355 students from public and private institutions through an online questionnaire between April and May 2023. Among participants,
Eduard F. Valenzuela +7 more
wiley +1 more source