Results 61 to 70 of about 2,217 (174)
Chemistry – A European Journal, Volume 32, Issue 28, 25 July 2026.The synthesis of 2‐methyl propellane and its conversion to various 1,2‐ and 1,2,3‐di‐ and trisubstituted bicyclopentanes is reported. Abstract Bicyclo[1.1.1]pentanes (BCPs) have emerged as isosteric replacements for mono‐ and para‐substituted benzene rings in medicinal and materials applications, involving substitution at the BCP bridgehead (1,3 ...
Sean R. Verschaeve +4 more
wiley +1 more source
1,3-Difunctionalization of [1.1.1]propellane through iron-hydride catalyzed hydropyridylation
Nature CommunicationsCurrent methodologies for the functionalization of [1.1.1]propellane primarily focus on achieving 1, 3-difunctionalized bicyclo[1.1.1]pentane or ring-opened cyclobutane moiety. Herein, we report an innovative approach for the 1, 3-difunctionalization of [
Changha Kim, Yuhyun Kim, Sungwoo Hong
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Mechanisms and Clinical Manifestations of Age‐Related Impairment in Wound Healing
International Wound Journal, Volume 23, Issue 7, July 2026.ABSTRACT Chronic wounds account for a considerable burden on the overall US healthcare system, affecting an estimated 10.2 million people and costing as much as $148 billion dollars in 2022 alone. Elderly patients suffer disproportionately, as nearly 85% of the chronic wound population is over the age of 65 years old.
Daniel A. Rabin +10 more
wiley +1 more source
Photochemistry and Photobiology, Volume 102, Issue 4, Page 845-853, July/August 2026.In a rabbit surgical field model seeded with polymicrobial flora, a single dose of 222‐nm UV‐C (500 mJ/cm2) markedly reduced bacterial colonies, achieving a bactericidal effect comparable to 254‐nm UV‐C (200 mJ/cm2), while no UV‐C irradiation showed heavy growth. Wound healing did not differ among groups. Microbiota profiling detected SSI‐relevant taxa
Tomoaki Fukui +11 more
wiley +1 more source
Veterinary Ophthalmology, Volume 29, Issue 4, July 2026.ABSTRACT Purpose Assess in vitro efficacy of a device emitting 265 nm UVC light against bacteria isolated from veterinary infectious keratitis. Methods Twenty‐seven clinically‐derived bacterial isolates: Staphylococcus pseudintermedius (n = 10; including n = 2 methicillin‐resistant Staphylococcus pseudintermedius [MRSP]), Staphylococcus aureus (n = 1),
Oliver Joe Williams +3 more
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SYNTHESIS OF CYCLOBUTANE ANALOGUES
Bulletin of the Chemical Society of Ethiopia, 2009 2-(3-Acetyl-2,2-dimethylcyclobutyl)acetic acid (pinonic acid) was synthesized using α-pinene as raw material and potassium permanganate as oxidant. This compound reacted with substituted aniline to produce eight kinds of derivatives with cyclobutane moiety. The yields of the cyclobutane analogues ranged from 24.9 to 78.2 %. KEY WORDS: Cyclobutane
Yan Bai Yin +4 more
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Revista de Ciências Farmacêuticas Básica e Aplicada, 2010 O objetivo deste trabalho é avaliar a eficácia e a segurança da dose de 20 mg/dia de sibutramina em voluntários obesos, com IMC superior a 35, e compará-las com a dose de 10 mg/dia e à mudança de estilo de vida de pacientes com IMC inferior a 35 (a ...
Carlos Alberto Menezes +4 more
doaj
The crystal structure of high cyclobutane [PDF]
Acta Crystallographica, 1953 Carter, Giles F., Templeton, D.H.
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Discovery of Potent 1,3-Cyclobutane-Containing Dual A<sub>2A</sub>/A<sub>2B</sub> Receptor Antagonists with Low Projected Human Dose for the Treatment of Cancer. [PDF]
ACS Med Chem LettBrill ZG +31 more
europepmc +1 more source