Results 81 to 90 of about 1,032 (168)
, 2016 A new synthesis of 2-alkoxy-1,1-cyclobutane diesters and their first use in dipolar cycloadditions is reported. Both the formation of the donor−acceptor cyclobutanes and their subsequent annulation with in situ formed imines are catalyzed by Yb(OTf)3 ...
Mahmoud M. Abd Rabo Moustafa (2130100) +1 more
core +1 more source
Acta Crystallographica Section E Structure Reports Online, 2007 The title compound, C4H4O2, was prepared as an intermediate in the synthesis of α-hydroxycyclopropanecarboxylic acid. The structure of this intermediate has only been deduced previously from 1H NMR spectra, elemental analysis or chemical derivatization.
Richard Betz, Peter Klüfers
openaire +1 more source
The Skin‐Lightening Efficacy and Mechanisms of Botanical Extracts: A Comprehensive Review
Journal of Cosmetic Dermatology, Volume 25, Issue 10, October 2026.ABSTRACT Background Skin pigmentation is regulated by a complex network involving melanogenesis, melanosome transfer, oxidative stress, environmental stimuli, and epidermal turnover. Botanical extracts and phytochemicals have attracted increasing interest as potential skin‐lightening agents. This review evaluates their efficacy, mechanisms, and safety.
Siting Yang +6 more
wiley +1 more source
Synthesis of Cyclobutanes Utilizing Green Chemistry
, 2015 The reactions of cyclobutanes is a topic that has yet to be thoroughly studied due to the challenges of working with the strained molecule. Cyclobutanes have been used as synthetic analogs for several different amino acids and biomolecules because of ...
Winfield, DeMichael
core
Cyclobutanes as well as 2‐substituted alkylidene cyclobutanes (ADCBs) are important skeletons in pharmaceuticals and versatile precursors in organic synthesis.
Zhan‐Ming Zhang +3 more
core +2 more sources
Nature CommunicationsThe direct C–H activation of inert C(sp3)–H bonds in a hydrocarbon chain has been a very attractive target in organic synthesis for many decades. Among all the variety of processes, those driven by vinyl carbocations are quite scarce thus far, and it is ...
Roman A. Novikov +6 more
doaj +1 more source
MoleculesThe photocycloaddition (PCA) of chalcones represents an important reaction pathway for accessing substituted cyclobutanes, which is a molecular framework with utility in synthetic chemistry, materials science, and medicine.
Joydip Chatterjee +4 more
doaj +1 more source
1,3-Difunctionalization of [1.1.1]propellane through iron-hydride catalyzed hydropyridylation
Nature CommunicationsCurrent methodologies for the functionalization of [1.1.1]propellane primarily focus on achieving 1, 3-difunctionalized bicyclo[1.1.1]pentane or ring-opened cyclobutane moiety. Herein, we report an innovative approach for the 1, 3-difunctionalization of [
Changha Kim, Yuhyun Kim, Sungwoo Hong
doaj +1 more source
Profiling crystal engineered ligands for targeting treatment resistant androgen receptors
Frontiers in PharmacologyIntroductionProstate cancer (PCa) is one of the principal contributors to health burden in the aging male population. PCa develops through dysregulation of androgen receptor (AR) signaling pathways.
Avan Navaz Colah +5 more
doaj +1 more source
A Practical Catalytic Method for Preparing Highly Substituted Cyclobutanes and Cyclobutenes
, 2016 Tf2NH, an organic acid, efficiently catalyzes (2 + 2) cycloaddition reactions of silyl enol ethers with acrylates or propiolate. The process affords highly substituted cyclobutanes in high yield with high stereoselectivity under practical and ...
Kiyosei Takasu (1557154) +2 more
core +1 more source