Results 21 to 30 of about 1,072 (175)

Enzymatic Synthesis of Phloretin α‐Glucosides Using a Sucrose Phosphorylase Mutant and its Effect on Solubility, Antioxidant Properties and Skin Absorption

Advanced Synthesis &Catalysis, Volume 363, Issue 12, Page 3079-3089, June 21, 2021., 2021
Abstract Glycosylation of polyphenols may increase their aqueous solubility, stability, bioavailability and pharmacological activity. Herein, we used a mutant of sucrose phosphorylase from Thermoanaerobacterium thermosaccharolyticum engineered to accept large polyphenols (variant TtSPP_R134A) to produce phloretin glucosides.
Jose L. Gonzalez‐Alfonso, Zorica Ubiparip, Elena Jimenez‐Ortega, Ana Poveda, Cristina Alonso, Luisa Coderch, Jesus Jimenez‐Barbero, Julia Sanz‐Aparicio, Antonio O. Ballesteros, Tom Desmet, Francisco J. Plou   +10 more
wiley   +1 more source

Research Progress on Enzymatic Preparation and Application of Large-Ring Cyclodextrin [PDF]

Shipin Kexue
Large-ring cyclodextrin (LR-CD) is a cyclic α-1,4-glucan consisting of nine to several hundred glucopyranose units. LR-CD is mainly prepared by the cyclization activity of cyclodextrin glucosyltransferase or 4-α-glucanotransferase that catalyzes ...
XIE Anning, JIN Zhengyu, LI Xiaoxiao, BAI Yuxiang
doaj   +1 more source

Perturbed cholesterol and vesicular trafficking associated with dengue blocking in Wolbachia-infected Aedes aegypti cells [PDF]

, 2017
Wolbachia are intracellular maternally inherited bacteria that can spread through insect populations and block virus transmission by mosquitoes, providing an important approach to dengue control.
Ant, Thomas H., Charles, Philip D., Dowle, Adam A., Geoghegan, Vincent, Hester, Svenja, Larson, Tony, Rainey, Stephanie M., Sinkins, Steven P., Stainton, Kirsty, Thomas, Benjamin   +9 more
core   +3 more sources

Conductive Hydrogels with Dynamic Reversible Networks for Biomedical Applications

Advanced Healthcare Materials, Volume 10, Issue 11, June 9, 2021., 2021
Dynamic conductive hydrogels (DCHs) are emerging as a promising and well‐utilized platform for 3D cell culture and tissue engineering to incorporate electron signals as biorelevant physical cues. DCHs can provide dynamic environments for cellular functions while maintaining matrix integrity. An overview of the design, synthesis, and engineering of DCHs
Yong Xu, Michelle Patino Gaillez, Rebecca Rothe, Sandra Hauser, Dagmar Voigt, Jens Pietzsch, Yixin Zhang   +6 more
wiley   +1 more source

Available technologies on improving the stability of polyphenols in food processing

Food Frontiers, Volume 2, Issue 2, Page 109-139, June 2021., 2021
Abstract Polyphenols are the most important phytochemicals in our diets and have received great attention due to their broad benefits for human health by suppressing oxidative stress and playing a protective role in preventing different pathologies such as cardiovascular disease, cancer, diabetes, and obesity.
Hui Cao, Oznur Saroglu, Ayse Karadag, Zoriţa Diaconeasa, Gianni Zoccatelli, Carlos Adam Conte‐Junior, Gustavo A. Gonzalez‐Aguilar, Juanying Ou, Weibin Bai, Cristina Mara Zamarioli, Luis Alexandre Pedro de Freitas, Avi Shpigelman, Pedro H. Campelo, Esra Capanoglu, Ching Lik Hii, Seid Mahdi Jafari, Yaping Qi, Pan Liao, Mingfu Wang, Liang Zou, Paula Bourke, Jesus Simal‐Gandara, Jianbo Xiao   +22 more
wiley   +1 more source

Production of highly bioactive resveratrol analogues pterostilbene and piceatannol in metabolically engineered grapevine cell cultures [PDF]

, 2017
Summary Grapevine stilbenes, particularly trans-resveratrol, have a demonstrated pharmacological activity. Other natural stilbenes derived from resveratrol such as pterostilbene or piceatannol, display higher oral bioavailability and bioactivity than the
Bru Martínez, Roque, Cusidó Vidal, Rosa M., Martínez Márquez, Ascensión, Morante Carriel, Jaime A., Palazón Barandela, Javier, Ramírez Estrada, Karla   +5 more
core   +4 more sources

Safety evaluation of the food enzyme β‐cyclodextrin glucanotransferase from Escherichia coli strain WCM105xpCM6420

EFSA Journal, 2020
The food enzyme β‐cyclodextrin glucanotransferase ((1→4)‐α‐d‐glucan 4‐α‐d‐[(1→4)‐α‐d‐glucano]‐transferase; EC 2.4.1.19) is produced with a genetically modified Escherichia coli strain WCM105xpCM6420 by Wacker Chemie GmbH. The production strain harbours a
EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), Vittorio Silano, José Manuel Barat Baviera, Claudia Bolognesi, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Claude Lambré, Evgenia Lampi, Marcel Mengelers, Alicja Mortensen, Gilles Rivière, Inger‐Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Jaime Aguilera, Natalia Kovalkovicova, Yi Liu, Joaquim Maia, Andrew Chesson   +22 more
doaj   +1 more source

Cyclic β-glucans at the bacteria–host cells interphase: One sugar ring to rule them all [PDF]

, 2018
Cyclic β‐1,2‐D‐glucans (CβG) are natural bionanopolymers present in the periplasmic space of many Proteobacteria. These molecules are sugar rings made of 17 to 25 D‐glucose units linked exclusively by β‐1,2‐glycosidic bonds.
Arce Gorvel, Vilma, Ciocchini, Andres Eduardo, Comerci, Diego José, Gorvel, Jean-Pierre, Guidolin, Leticia Soledad   +4 more
core   +1 more source

Recent development of nanomedicine for the treatment of bacterial biofilm infections

VIEW, Volume 2, Issue 1, February 2021., 2021
Bacterial biofilm related infections are ever growing threats for global medical community. However, traditional antibiotic therapy is usually ineffective for eradicating bacterial biofilms. In this review, recent development of nanomedicine to treat bacterial biofilm infections is introduced, and typical therapeutic strategies based on nanotechnology ...
Weijun Xiu, Jingyang Shan, Kaili Yang, Hang Xiao, Lihui Yuwen, Lianhui Wang   +5 more
wiley   +1 more source

Environmentally benign glycosylation of aryl pyranosides and aryl/alkyl furanosides demonstrating the versatility of thermostable CGTase from Thermoanaerobacterium sp. [PDF]

, 2014
International audienceAn extensive study on the specificity of transglycosylation and disproportionation of Thermoanaerobacterium sp. cyclodextrin glucosyltranferases against aryl glucopyranosides or furanosides was achieved. While a mixture of maltoside
Chauvin, Anne-Laure, Ferrières, Vincent, Herrera-Estrella, Luis, Legentil, Laurent, Nugier-Chauvin, Caroline, Pennec, Alizé   +5 more
core   +3 more sources