Results 1 to 10 of about 5,356 (161)

Investigation of Cytotoxicity and Cell Uptake of Cationic Beta-Cyclodextrins as Valid Tools in Nasal Delivery [PDF]

Pharmaceutics, 2020
Cyclodextrin polymers have high applicability in pharmaceutical formulations due to better biocompatibility, solubility enhancement, loading capacity and controlled drug release than their parent, cyclodextrins.
Giovanna Rassu, Silvia Fancello, Marta Roldo, Milo Malanga, Lajos Szente, Rossana Migheli, Elisabetta Gavini, Paolo Giunchedi   +7 more
doaj   +2 more sources

Bisphenol A Adsorption on Silica Particles Modified with Beta-Cyclodextrins [PDF]

Nanomaterials, 2021
This study presents the synthesis of silica particles bearing two beta-cyclodextrin (BCD) (beta-cyclodextrin-BCD-OH and diamino butane monosubstituted beta-cyclodextrin-BCD-NH2).
Stefan Bucur, Aurel Diacon, Ionel Mangalagiu, Alexandra Mocanu, Florica Rizea, Adrian Dinescu, Adi Ghebaur, Aurelian Cristian Boscornea, Georgeta Voicu, Edina Rusen   +9 more
doaj   +2 more sources

Stability, Antioxidant Activity and Intestinal Permeation of Oleuropein Inclusion Complexes with Beta-Cyclodextrin and Hydroxypropyl-Beta-Cyclodextrin

Molecules, 2022
Compared to beta-cyclodextrins (beta-CD), hydroxypropyl-beta-cyclodextrins (HP-beta-CD) are a more popular material used to prepare inclusion complexes due to their superior solubility and intestinal absorption.
Hui Liu, Jinhua Luo, Ping Yang, Xiulan Yang, Jun Yan, Qian Yao   +5 more
doaj   +3 more sources

Characterization of hydroxypropyl-beta-cyclodextrins used in the treatment of Niemann-Pick Disease type C1. [PDF]

PLoS ONE, 2017
2-Hydroxypropyl-beta-cyclodextrin (HPβCD) has gained recent attention as a potential therapeutic intervention in the treatment of the rare autosomal-recessive, neurodegenerative lysosomal storage disorder Niemann-Pick Disease Type C1 (NPC1).
Alfred L Yergey, Paul S Blank, Stephanie M Cologna, Peter S Backlund, Forbes D Porter, Allan J Darling   +5 more
doaj   +2 more sources

Correction: Characterization of hydroxypropyl-beta-cyclodextrins used in the treatment of Niemann-Pick Disease type C1. [PDF]

PLoS ONE, 2018
[This corrects the article DOI: 10.1371/journal.pone.0175478.].
Alfred L Yergey, Paul S Blank, Stephanie M Cologna, Peter S Backlund, Forbes D Porter, Allan J Darling   +5 more
doaj   +2 more sources

Beta-cyclodextrins in infectious disease therapy: A review of their function beyond simple drug carriers

Carbohydrate Polymer Technologies and Applications
Cyclodextrins (CDs) are cyclic oligosaccharides derived from starch through enzymatic conversion. Over the past decades, CDs and their derivatives (dCDs) have attracted significant interest due to their remarkable versatility and distinctive ...
Priscille Brodin, Ruxandra Gref, Arnaud Machelart   +2 more
exaly   +3 more sources

Significantly improving the solubility and anti-inflammatory activity of fenofibric acid with native and methyl-substituted beta-cyclodextrins via complexation [PDF]

Scientific Reports
The solubility of commonly used anti-inflammatory drugs has become a significant concern in contemporary medicine. Furthermore, inflammatory arthritis stands out as the most prevalent chronic inflammatory disease globally.
Rajaram Rajamohan, Perumal Muthuraja, Kuppusamy Murugavel, Murali Krishnan Mani, D. S. Prabakaran, Jeong Hyun Seo, Tabarak Malik, Yong Rok Lee   +7 more
doaj   +2 more sources

Antimicrobial Activities of Pistacia lentiscus Essential Oils Nanoencapsulated into Hydroxypropyl-beta-cyclodextrins [PDF]

ACS Omega
Obaydah Abd Alkader Alabrahim, Hassan Mohamed El-Said Azzazy   +1 more
doaj   +2 more sources

Cellular Effects of Cyclodextrins: Studies on HeLa Cells

Molecules, 2022
Cyclodextrins are high molecular weight, hydrophilic, cyclic, non-reducing oligosaccharides, applied as excipients for the improvement of the solubility and permeability of insoluble active pharmaceutical ingredients.
Ágnes Rusznyák, Mercédesz Palicskó, Milo Malanga, Éva Fenyvesi, Lajos Szente, Judit Váradi, Ildikó Bácskay, Miklós Vecsernyés, Katalin Szászné Réti-Nagy, Gábor Vasvári, Ádám Haimhoffer, Ferenc Fenyvesi   +11 more
doaj   +1 more source

Thermal Stabilization of the Betalain Extract Using Encapsulation and Co-pigmentation and its Application in the Model Drink [PDF]

Pizhūhish va Nuāvarī dar ̒Ulūm va Sanāyi̒-i Ghaz̠āyī, 2021
One of the important challenges about using of the betalains is their low stability against light and heat. Therefore, the main goal of this research was to stabilize the extracted betalain from red beet against thermal treatments.
Hamed Saberian, Vahid Pasban Noghabi
doaj   +1 more source