Results 21 to 30 of about 574,698 (305)
The absorption, distribution and excretion of intravenously and orally administered beta-cyclodextrin (beta-CD) and glucosyl (G)-beta-CD in rats were studied using HPLC with pulsed amperometric detection. Within 10 h after intravenous administration, unchanged beta-CD and G-beta-CD recovered in urine were about 90% of each dose.
KUBOTA, Yoko +3 more
openaire +3 more sources
Background The isoflavonoid genistein represents the major active compound from soybean, the vegetal product from Glycine max (Fabaceae). The aim of this study is to prove that genistein was incorporated in two semisynthetic cyclodextrins, beta ...
Danciu CorinaTiulea +6 more
doaj +1 more source
Puerariae Lobatae Radix (PLR), a well-known herbal medicine, is the root of Pueraria lobata (Willd.) Ohwi and has been employed for the treatment and prevention of cardiovascular and cerebrovascular diseases.
Tao Feng +5 more
doaj +1 more source
Microanalytical methods were developed for measuring galactosyl-beta-cyclodextrin (Gal-betaCD) and mannosyl (Man)-betaCD in biological matrices of the rat by HPLC with pulsed amperometric detection. Then, using these methods, the absorption, distribution and excretion of intravenously and orally administered Gal-betaCD and Man-betaCD were determined in
KUBOTA, Yoko +2 more
openaire +3 more sources
Screening of Cyclodextrins in the Processing of Buserelin Dry Powders for Inhalation Prepared by Spray Freeze-Drying [PDF]
Purpose: In this study, we prepared inhalable buserelin microparticles using the spray freeze-drying (SFD) method for pulmonary drug delivery. Raffinose as a cryoprotectant carrier was combined with two levels of five different cyclodextrins (CDs) and ...
Mostafa Rostamnezhad +5 more
doaj +1 more source
Beta-Cyclodextrins as affordable antivirals to treat coronavirus infection [PDF]
The SARS-CoV-2 pandemic made evident that we count with few coronavirus-fighting drugs. Here we aimed to identify a cost-effective antiviral with broad spectrum activity and high safety and tolerability profiles.
Blanco, Julià +21 more
core +1 more source
Antihistamines such as levocetirizine dihydrochloride (LC) are commercially used in oral tablets and oral drops to reduce allergic symptoms. In this study, LC was nano-spray-dried using three mucoadhesive polymers and four cyclodextrin species to form ...
Mirella Mirankó +4 more
doaj +1 more source
Study of the dermal anti-inflammatory, antioxidant, and analgesic activity of pinostrobin
Pinostrobin is a flavanone isolated from Renealmia alpinia (Rottb.) Maas, which is used to treat painful diseases and ailments; indigenous peoples use it as plasters.
Alejandro Serna González +2 more
doaj +1 more source
Mansonone G (MG), a plant-derived compound isolated from the heartwood of Mansonia gagei, possesses a potent antitumor effect on several kinds of malignancy. However, its poor solubility limits the use for practical applications. Beta-cyclodextrin (β
Panupong Mahalapbutr +5 more
doaj +1 more source
The Preservation and Enantiomeric Selection of Linalool by Nanoencapsulation Using Cyclodextrins
Linalool, a volatile terpene alcohol, is responsible for a characteristic aroma in food, beverages, and cosmetics. However, linalool’s low aqueous solubility and high volatility limit the applications and shelf life of linalool-containing products ...
Tanaporn Poonphatanapricha +4 more
doaj +1 more source

