Results 11 to 20 of about 574,698 (305)
The present work aimed to investigate inclusion complexes of squalene with various cyclodextrins (native β-cyclodextrin and methyl-β-cyclodextrin). The production of squalene-β-cyclodextrin inclusion complex was obtained using Response Surface Methodology and obtained inclusion complexes were studied with FTIR spectroscopy, X-ray diffractometry ...
Van NGUYEN, Anh +5 more
openaire +2 more sources
Zinc diethyldithiocarbamate (Zn (DDC)2), a disulfiram metabolite (anti-alcoholism drug), has shown a strong anti-cancer activity in vitro. However, its application was limited by its low aqueous solubility and rapid metabolism.
Ayşe Kaya +6 more
doaj +1 more source
Rutin is a natural flavonoid that carries out a variety of biological activities, but its application in medicine and food is limited by its water solubility.
Chaokang Chang +5 more
doaj +1 more source
Fluorescently labeled methyl-beta-cyclodextrin enters intestinal epithelial Caco-2 cells by fluid-phase endocytosis. [PDF]
Cyclodextrins are widely used excipients for increasing the bioavailability of poorly water-soluble drugs. Their effect on drug absorption in the gastrointestinal tract is explained by their solubility- and permeability-enhancement.
Ferenc Fenyvesi +12 more
doaj +1 more source
Investigation of Copper Ion Adsorption by Alpha, Beta and Gamma Cyclodextrin by Density Function Method [PDF]
Cyclodextrins are categorized into three groups of alpha, beta, and gamma, according to the number of their own glucose units of 6, 7 and 8 units. These ring compounds have two surfaces of hydrophilic and hydrophobic to trap compounds with different ...
Hosein Nourmohamadi +2 more
doaj +1 more source
Despite advancements in contemporary therapies, cardiovascular disease from atherosclerosis remains a leading cause of mortality worldwide. Supported lipid bilayers (SLBs) are membrane interfaces that can be constructed with varying lipid compositions ...
Peter A. Chiarelli +13 more
core +1 more source
Liquid Silyl Derivative of beta-Cyclodextrin [PDF]
© ISUCT Publishing. Per-6-O-(tert-butyl)(diphenyl)silyl-β-cyclodextrin was found to form metastable liquid phase, which is unusual for cyclodextrin mono-derivatives under ambient conditions. Also, it can exist in a solid amorphous state as a stable molecular glass.
Gatiatulin A. +5 more
openaire +2 more sources
Monitoring of complex forming of the active pharmaceutical substance and β-cyclodextrin as an additive of the mobile phase using mass spectrometry [PDF]
In recent years, there is aim to reduce toxic solvents use in chromatographic techniques. Beta-cyclodextrins (β-CD) are commonly used for this purpose, as substance retention modulators.
Milenković Anđela +4 more
doaj +1 more source
Melarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human African trypanosomiasis [PDF]
Human African trypanosomiasis (HAT), or sleeping sickness, results from infection with the protozoan parasites <i>Trypanosoma brucei</i> (<i>T.b.</i>) <i>gambiense</i> or <i>T.b.rhodesiense</i> and is ...
Jones, A. +35 more
core +1 more source
Use of cyclodextrins for manipulating cellular cholesterol content
Previous studies from this laboratory have demonstrated that exposure of tissue culture cells to cyclodextrins results in rapid cholesterol depletion.
A E Christian +3 more
doaj +1 more source

