Turn-Induction in Peptides Incorporating Novel Cyrene-Derived α,α-Disubstituted Amino Acid. [PDF]
J Pept SciNovel chiral cyrene‐derived Cyr residues were incorporated into peptides. The α,α‐disubstituted amino acid residue was introduced using the Ugi reaction. X‐ray crystallographic analysis of R‐ and S‐Cyr residues indicated preference to adopt left‐ and right‐handed α‐helical conformations, respectively.
Bhowal KB, Hitti R, Lubell WD.
europepmc +2 more sources
Tomato-Soy Juice Reduces Inflammation and Modulates the Urinary Metabolome in Adults With Obesity. [PDF]
Mol Nutr Food ResCompared to pre‐intervention, consuming a tomato‐soy juice (54 mg lycopene, 189 mg soy isoflavones/d) reduced levels of inflammatory cytokines (IL‐5, IL‐12p70, and GM‐CSF, with TNF‐alpha trending downward), increased plasma lycopene and urinary soy isoflavone metabolites, and altered the urinary metabolome. ABSTRACT Chronic, low‐grade inflammation is a
Sholola MJ +6 more
europepmc +2 more sources
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF); Scientific Opinion on Flavouring Group Evaluation 12, Revision 2 (FGE.12Rev2): Primary saturated or unsaturated alicyclic alcohol, aldehyde, acid, and esters from chemical group 7 [PDF]
, 2011 The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate 10 flavouring substances in the Flavouring Group Evaluation 12 (FGE.12), including an additional substance in ...
Arndt +48 more
core +3 more sources
Aromatization of Cyclohexanecarboxylic Acid
Journal of Biological Chemistry, 1966 Abstract An enzyme which catalyzes the aromatization of cyclohexanecarboxyl coenzyme A has been isolated from whole liver as well as from liver mitochondria. Incubation of the soluble, partially purified enzyme with cyclohexanecarboxyl-CoA produces cyclohexene-1-carboxyl-CoA, benzoyl-CoA, and a polar compound which has not been further characterized ...
B M, Babior, K, Bloch
openaire +2 more sources
The use of Lewis acid AlCl3 as a promoter in the Pd-complex catalytic system of the cyclohexene hydroethoxycarbonylation reaction [PDF]
, 2021 This paper presents the results of detailed studies of the possibility of using Lewis acid AlCl3 as a promoter of the catalytic three-component system PdCl2(PPh3)2–PPh3–AlCl3 in the hydroethoxycarbonylation reaction of cyclohexene at low carbon monoxide ...
Almatkyzy P. +7 more
core +1 more source
Characterisation of the aroma of green mexican coffee and identification of mouldy/earthy defect [PDF]
, 2001 Erworben im Rahmen der Schweizer Nationallizenzen (http://www.nationallizenzen.ch)The aromas of a reference green Mexican coffee (Arabica) and of a coffee from the same origin, but having a pronounced earthy/mouldy off-taint, were characterised.
Amado, Rentato +5 more
core +1 more source
A practical synthesis of Rho-Kinase inhibitor Y-27632 and fluoro derivatives and their evaluation in human pluripotent stem cells [PDF]
, 2011 A practical synthesis of the Rho-Kinase inhibitor Y-27632 and two new fluoro derivatives was achieved in seven steps and with a good overall yield of 45% starting from commercially available (R)-1-phenylethylamine.
Dräger, Gerald +5 more
core +2 more sources
Efficient and Mild Microwave-Assisted Stepwise Functionalization of Naphthalenediimide with α-Amino Acids [PDF]
, 2006 Microwave dielectric heating proved to be an efficient method for the one-pot and stepwise syntheses of symmetrical and unsymmetrical naphthalenediimide derivatives of α-amino acids.
Otto, Sijbren, +3 more
core +4 more sources
Modulation of Amide Bond Rotamers in 5-Acyl-6,7-dihydrothieno[3,2-c]pyridines [PDF]
, 2015 2-Substituted N-acyl-piperidine is a widespread and important structural motif, found in approximately 500 currently available structures, and present in nearly 30 pharmaceutically active compounds.
Lanyon-Hogg, T +5 more
core +3 more sources
trans-4-(Phenoxymethyl)cyclohexanecarboxylic acid [PDF]
Acta Crystallographica Section E Structure Reports Online, 2008 The title compound, C(14)H(18)O(3), is an important model compound in the synthesis of phenolic ethers. The cyclo-hexane ring adopts a chair conformation. In the crystal structure, adjacent mol-ecules are linked by O-H⋯O hydrogen bonds.
Hu Zheng +3 more
openaire +3 more sources