[2]-Ladderanes as isosteres for meta-substituted aromatic rings and rigidified cyclohexanes [PDF]
Nature Communications, 2022 The development of new classes of isosteres and building blocks is crucial to the advancement of medicinal chemistry programs. Here, the authors report the synthesis and development of ladderanes to act as replacements for meta-substituted aromatic rings
Rachel C. Epplin +10 more
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Stereoselective Synthesis of Multisubstituted Cyclohexanes by Reaction of Conjugated Enynones with Malononitrile in the Presence of LDA [PDF]
Molecules, 2020 Reaction of linear conjugated enynones, 1,5-diarylpent-2-en-4-yn-1-ones, with malononitrile in the presence of lithium diisopropylamide LDA, as a base, in THF at room temperature for 3–7 h resulted in the formation of the product of dimerization ...
Anastasiya V. Igushkina +4 more
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Living supramolecular polymerization of fluorinated cyclohexanes [PDF]
Nature Communications, 2021 Living supramolecular polymerization can produce precise covalent polymers, but the scope of monomers is still narrow. Here the authors show a molecular platform for living supramolecular polymerization that is based on the unique structure of all-cis 1 ...
Oleksandr Shyshov +8 more
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Comprehensive Thermodynamic Study of Alkyl-Cyclohexanes as Liquid Organic Hydrogen Carriers Motifs
Hydrogen, 2023 Alkyl-cyclohexanes can be considered as suitable model compounds to understand the thermochemistry of aromatic compounds and their hydrogenated counterparts discussed as Liquid Organic Hydrogen Carrier systems.
Sergey P. Verevkin +4 more
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Supramolecular Polymerization of all-cis-Fluorinated Cyclohexanes: Influence of Side Chains
Organic Materials, 2023 Custom-designed materials based on supramolecular polymers are of interest for applications in organic electronics and biomedicine. Recently, we have shown that derivatives of the highly polar compound all-cis hexafluorocyclohexane undergo seeded ...
Shyamkumar V. Haridas +2 more
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A Theoretical Kinetic Study on Concerted Elimination Reaction Class of Peroxyl-hydroperoxyl-alkyl Radicals (•OOQOOH) in Normal-alkyl Cyclohexanes [PDF]
Molecules, 2023 The concerted elimination reaction class of peroxyl-hydroperoxyl alkyl radicals (•OOQOOH) plays a crucial role in the low-temperature combustion of normal-alkyl cyclohexanes.
Xiaoxia Yao, Jilong Zhang, Yifei Zhu
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Conformational Analysis Explores the Role of Electrostatic Nonclassical CF···HC Hydrogen Bonding Interactions in Selectively Halogenated Cyclohexanes. [PDF]
J Org ChemThe conformational equilibria of selectively halogenated cyclohexanes are explored both experimentally (VT-NMR) for 1,1,4,-trifluorocyclohexane 7 and by computational analysis (M06-2X/aug-cc-pVTZ level), with the latter approach extending to a wider ...
He M +3 more
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Computational Kinetic Study on the Intramolecular H-Migration of Hydroperoxyalkylperoxy Radicals (•OOQOOH) in Normal-Alkyl Cyclohexanes [PDF]
MoleculesHydroperoxyalkylperoxy radicals (•OOQOOH) are important intermediates in the low-temperature oxidation chemistry of conventional fuels. In these species, a hydrogen atom may migrate from a non-adjacent carbon to the peroxy group, forming a ...
Xiaoxia Yao, Juanqin Li, Zerong Li
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Stereoselective intermolecular radical cascade reactions of tryptophans or ɤ-alkenyl-α-amino acids with acrylamides via photoredox catalysis [PDF]
Nature Communications, 2022 Photocatalytic radical cascade reactions enable the facile construction of diverse cyclic compounds, though they rely on templated precursors. In this paper, the authors report on stereoselective intermolecular radical cascade reaction between tryptophan
Jiang-Tao Li +5 more
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Molecules, 2020 Conformational analysis of Si-mono- and Si,Si-disubstituted silacyclohexanes as well as their analogues with a heteroatom(s) in the ring is reviewed with the focus on the recent results.
Bagrat A. Shainyan
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