[2]-Ladderanes as isosteres for meta-substituted aromatic rings and rigidified cyclohexanes [PDF]
Nature Communications, 2022 The development of new classes of isosteres and building blocks is crucial to the advancement of medicinal chemistry programs. Here, the authors report the synthesis and development of ladderanes to act as replacements for meta-substituted aromatic rings
Jay F Larrow +2 more
exaly +4 more sources
Comprehensive Thermodynamic Study of Alkyl-Cyclohexanes as Liquid Organic Hydrogen Carriers Motifs [PDF]
Hydrogen, 2023 Alkyl-cyclohexanes can be considered as suitable model compounds to understand the thermochemistry of aromatic compounds and their hydrogenated counterparts discussed as Liquid Organic Hydrogen Carrier systems.
Sergey P. Verevkin +4 more
doaj +4 more sources
Stereoselective Synthesis of Multisubstituted Cyclohexanes by Reaction of Conjugated Enynones with Malononitrile in the Presence of LDA [PDF]
Molecules, 2020 Reaction of linear conjugated enynones, 1,5-diarylpent-2-en-4-yn-1-ones, with malononitrile in the presence of lithium diisopropylamide LDA, as a base, in THF at room temperature for 3–7 h resulted in the formation of the product of dimerization ...
Anastasiya V. Igushkina +4 more
doaj +3 more sources
Living supramolecular polymerization of fluorinated cyclohexanes
Nature Communications, 2021 Living supramolecular polymerization can produce precise covalent polymers, but the scope of monomers is still narrow. Here the authors show a molecular platform for living supramolecular polymerization that is based on the unique structure of all-cis 1 ...
Andrea Gardin +2 more
exaly +3 more sources
The Emergence and Properties of Selectively Fluorinated ‘Janus’ Cyclohexanes [PDF]
The chemical record, 2023 This account describes the evolution of a research programme that started by linking fluoromethylene (−CHF−) groups along aliphatic chains and then progressing to alicyclic rings with contiguous fluorine atoms. Different stereoisomers of aliphatic chains
D. O'Hagan
semanticscholar +4 more sources
A Theoretical Kinetic Study on Concerted Elimination Reaction Class of Peroxyl-hydroperoxyl-alkyl Radicals (•OOQOOH) in Normal-alkyl Cyclohexanes [PDF]
Molecules, 2023 The concerted elimination reaction class of peroxyl-hydroperoxyl alkyl radicals (•OOQOOH) plays a crucial role in the low-temperature combustion of normal-alkyl cyclohexanes.
Xiaoxia Yao, Jilong Zhang, Yifei Zhu
doaj +2 more sources
Structure and mobility of cyclohexane as a solvent for Trans-Polyisoprene [PDF]
PCCP 4(11) 2269-2272 (2002), 2002 Solutions of {\it trans}$-$polyisoprene in cyclohexane are investigated in atomistic detail at different compositions at two different temperatures. We investigate the influence of polymer concentration on the dynamics of the solvent molecules and the structure of the solvation shell.
Faller, Roland
arxiv +3 more sources
Stereoselective intermolecular radical cascade reactions of tryptophans or ɤ-alkenyl-α-amino acids with acrylamides via photoredox catalysis [PDF]
Nature Communications, 2022 Photocatalytic radical cascade reactions enable the facile construction of diverse cyclic compounds, though they rely on templated precursors. In this paper, the authors report on stereoselective intermolecular radical cascade reaction between tryptophan
Jiang-Tao Li +5 more
doaj +2 more sources
Computational studies of Brønsted acid-catalyzed transannular cycloadditions of cycloalkenone hydrazones. [PDF]
Beilstein J Org Chem, 2023 The contribution to the energy barrier of a series of tethers in transannular cycloadditions of cycloalkenes with hydrazones has been computationally studied by using DFT.
Pedrón M +5 more
europepmc +3 more sources
Catalytic Asymmetric Synthesis of Cyclohexanes by Hydrogen Borrowing Annulations
Angewandte Chemie - International Edition, 2019 Hydrogen borrowing catalysis serves as a powerful alternative to enolate alkylation, enabling the direct coupling of ketones with unactivated alcohols.
Fernanda Duarte +2 more
exaly +4 more sources