Results 51 to 60 of about 3,977 (186)

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Sequential Carboborylation–Suzuki Coupling of α,β‐Unsaturated Tosylhydrazones: A Dual CC Bond‐Forming Strategy for Molecular Diversification

ChemistryEurope
The one‐pot three‐component process involving N‐tosylhydrazones derived from cyclic α,β‐unsaturated ketones, alkylboronic acids, and aryl halides is reported.
Álvaro Valdés‐Maqueda, Manuel Plaza, Carlos Valdés   +2 more
doaj   +1 more source

Mapping the internal recognition surface of an octanuclear coordination cage using guest libraries [PDF]

, 2014
Size and shape criteria for guest binding inside the cavity of an octanuclear cubic coordination cage in water have been established using a new fluorescence displacement assay to quantify guest binding.
Adams H., Adriaenssens L., Ajami D., Ajami D., Ajami D., Alvarez S., Amenta V., Amenta V., Amenta V., Amouri H., Amouri H., Ams M. R., Andrews P. R., Asadi A., Barry N. P. E., Bolliger J. L., Bradshaw D., Breiner B., Brown C. J., Browne C., Brumaghim J. L., Buurma N. J., Chakrabarty R. J., Chang J. C., Chekmeneva E., Christopher A. Hunter, Cisse L., Clever G. H., Clever G. H., Clever G. H., Coles S. J., Collet A., Comby S., Conn M. M., Corbellini F., Cram D. J., Cram D. J., Cram D. J., Custelcean R., Desmarets C., Dolomanov O. V., Fiedler D., Fujita M., Galan A., Ha J.-H., Hamilton T. D., Han M., Harris K., Hastings C. J., Hastings C. J., Hatakeyama Y., Hof F., Hooley R. J., Horiuchi S., Houk K. N., Hummer G., Hunter C. A., Hunter C. A., Hunter C. A., Hunter C. A., Hunter C. A., Hunter C. A., Ichihara H., Inokuma Y., Inokuma Y., Inokuma Y., Jiang W., Jin P., Jinks M. A., Kawano M., Kerckhoffs J. M. C. A., Kishi N., Kishi N., Kopilevich S., Laughrey Z., Lewis J. E. M., Livingstone J. R., Mal P., Martina Whitehead, Mecozzi S., Metherell A. J., Meyer E. A., Michael D. Ward, Moerkerke S., Murase T., Nakamura T., Nassimbeni L. R., Nau W. M., Nishioka Y., O’Neil E. J., Perry J. J., Pluth M. D., Pratt L. R., Purse B. W., Rebek J., Rebek J., Reynolds J. A., Rieth S., Ronson T. K., Samanta D., Sawada T., Seidel S. R., Serrano L., Serrano L., Sheldrick G. M., Shenoy S. R., Sherman J. C., Simon Turega, Slovak S., Smulders M. M. J., Smulders M. M. J., Snyder P. W., Southall N. T., Spolar R. S., Spolar R. S., Spolar R. S., Sun H., Takano K., Tanford C., Therrien B., Tidmarsh I. S., Turega S., Turega S., Vallone B., Vannoy C. H., Ward M. D., Ward M. D., Whitehead M., William Cullen, Williams A. F., Yamauchi Y., Yi J. W., Yoshizawa M., Yoshizawa M., Yoshizawa M., Yoshizawa M.   +135 more
core   +3 more sources

Electronic Smoking Devices Among University Students: Usage Patterns and Chemical Composition of Inhaled Substances

Analytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT This study investigated the prevalence of electronic smoking device (ESD) use and its associated behavioural and chemical risks among university students in Bahia, Brazil. A cross‐sectional survey was conducted with 355 students from public and private institutions through an online questionnaire between April and May 2023. Among participants,
Eduard F. Valenzuela, Raffael Silva Santos Almeida, Ivana Ferreira Simões, Aline Gonçalves Miranda, Magno Oliveira Ramos, Roberto Rodrigues Bandeira Tosta Maciel, Fernanda Warken Rosa, Aníbal de Freitas Santos Júnior   +7 more
wiley   +1 more source

Strategies for the synthesis of enantiopure compounds focused on organocatalysis [PDF]

, 2012
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32393The preparation of enantiomerically pure compounds (EPC) is a continuous social demand due to the clinical advantages that enantiopure drugs offer over the racemic forms. Here, the best
Arróniz, Carlos, Escolano Mirón, Carmen   +1 more
core  

Vibrational Excitons in CH-Stretching Fundamental and Overtone Vibrational Circular Dichroism Spectra [PDF]

, 2005
A set of vibrational circular dichroism (VCD) spectra in the CH-stretching fundamental region for about twenty compounds belonging to the class of essential oils was empirically analyzed by the use of a sort of vibrational exciton mechanism, involving ...
ABBATE S, GANGEMI R, LAUX L, LEBON F, LONGHI G   +4 more
core   +1 more source

Cycloaddition Reactions of Carbonyl Compounds Possessing High Energy Content [PDF]

, 1971
Detailed structure and kinetic analyses of the photocycloaddition of alkanones to (a) α,β-unsaturated nitriles and (b) enol ethers have been performed. The excited singlet states of alkanones were found to add stereospecifically and regiospecifically to ...
Turro, Nicholas J.
core   +2 more sources

Light‐Induced Reactions of Small‐Membered Cyclic Carbonyl Compounds

European Journal of Organic Chemistry, Volume 29, Issue 10, 9 March 2026.
This review highlights recent advances in the synthesis and photochemical reactivity of cyclopropenone and cyclobutenedione. These compounds undergo photolysis upon direct excitation, and in some cases, through indirect excitation by photocatalysts. The resulting photogenerated species exhibit unique reactivity profiles that are strongly influenced by ...
Kenji Mishiro
wiley   +1 more source

Effect of structural ordering of the carbon support on the behavior of Pd catalysts in aqueous-phase hydrodechlorination [PDF]

, 2019
Catalysts consisting of Pd supported on virgin and heat-treated carbon blacks (homemade and commercial), graphites (natural and synthetic) and commercial carbon nanofibers were prepared and tested in the aqueous phase hydrodechlorinaton (HDC) of 4 ...
Alonso-Morales, Noelia, Baeza, José A., Calvo, Luisa, Eser, Semih, Gilarranz, Miguel A., Heras, Francisco, Rodríguez, Juan J.   +6 more
core   +1 more source

Chiral Potassium Brønsted Base‐Catalyzed Stereoselective Synthesis of 1,3‐Diols via a Tandem Allylic Isomerization/Asymmetric Aldol–Tishchenko Reaction

Advanced Synthesis &Catalysis, Volume 368, Issue 5, 3 March 2026.
Chiral potassium base catalysts featuring 1,1´‐bi‐2‐naphthol‐derived chiral crown ethers as ligands promote a tandem allylic isomerization/asymmetric aldol‐Tishchenko reaction of allylic alcohols and aldehydes. This method provides enantioenriched 1,3‐diols with excellent diastereoselectivity and high enantioselectivity, thereby expanding the synthetic
Hiroki Ishikawa, Masahiro Sai
wiley   +1 more source