Results 201 to 210 of about 107,900 (262)

Cyclooxygenase-1 and cyclooxygenase-2 densities measured using positron emission tomography are not altered in the brains of individuals with stable multiple sclerosis. [PDF]

open access: yesJ Cereb Blood Flow Metab
Tang S   +11 more
europepmc   +1 more source

Cyclooxygenase-2 and carcinogenesis

Biochimica Et Biophysica Acta: Reviews on Cancer, 2000
Numerous investigations have shown that COX-2 is a participant in the pathway of colon carcinogenesis, especially when mutation of the APC tumor suppressor is the initiating event. Moreover, it seems that the amount of COX-2 is important, since there is a correlation between its level of expression and the size of the tumors and their propensity to ...
Stephen M Prescott, F A Fitzpatrick
exaly   +3 more sources

Cyclooxygenase-2 and atherosclerosis

Current Opinion in Lipidology, 2002
Cyclooxygenase regulates the production of eicosanoids, which modulate physiologic processes in the vessel wall contributing to atherosclerosis and thrombosis, including platelet aggregation, control of vascular tone, and the local inflammatory response.
MacRae F, Linton, Sergio, Fazio
openaire   +2 more sources

Cyclooxygenase 2 and the kidney

Current Opinion in Nephrology and Hypertension, 2001
Cyclooxygenase metabolizes arachidonic acid to a family of bioactive fatty acids designated prostaglandins. Two isoforms of cyclooxygenase exist, designated COX1 and COX2. These isoforms are expressed in distinct but important areas of the kidney. COX1 predominates in vascular smooth muscle and collecting ducts, whereas COX2 predominates in the macula ...
M D, Breyer, R C, Harris
openaire   +2 more sources

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