Results 31 to 40 of about 24,541,782 (296)

Cyclooxygenase-2 Expression in Bladder Cancer and Patient Prognosis: Results from a Large Clinical Cohort and Meta-Analysis [PDF]

, 2012
27/02/14 meb.
Manuel M. Morente (135761), Real, FX, Real, Francisco X., Morente, Manuel M., Kogevinas, Manolis, Adonina Tardón, SBC/EPICURO investigators, Real Francisco X., Montes-Moreno, S, Montes-Moreno Santiago, Carrato, Alfredo, Amaral André F. S., Maciej J Czachorowski, André F. S. Amaral (135752), Maciej J. Czachorowski (135750), Santiago Montes-Moreno, Czachorowski, Maciej J., Malats Núria, Morente, MM, Santiago Montes-Moreno (135753), Kogevinas, M, André F S Amaral, Manolis Kogevinas, Amaral, André F.S., Amaral, André F. S., Tardón Adonina, Czachorowski, Maciej J, Morente, Manuel M, Josep Lloreta, Manolis Kogevinas (135763), Francisco X Real, Carrato Alfredo, Alfredo Carrato (135757), Tardón, Adonina, Malats, N, Morente Manuel M., Montes Moreno, Santiago, Tardón García, Adonina, Czachorowski Maciej J., Núria Malats (135767), Malats i Riera, Núria, Kogevinas Manolis, Alfredo Carrato, Carrato, A, Francisco X. Real (135765), Adonina Tardón (135759), Montes-Moreno, Santiago, Lloreta, Josep, Josep Lloreta (135755), Malats Riera, Núria, Carrato Mena, Alfredo, Núria Malats, Lloreta Josep, Manuel M Morente, Tardón, A, Lloreta, J, Czachorowski, MJ, Amaral, AFS, Lloreta, Josep, 1958-   +58 more
core   +1 more source

Antitumor enhancement of celecoxib, a selective Cyclooxygenase-2 inhibitor, in a Lewis lung carcinoma expressing Cyclooxygenase-2

Journal of Experimental & Clinical Cancer Research, 2008
Background The goal of this study was to determine the effects of a selective Cyclooxygenase (COX)-2 inhibitor on the inhibition of tumor growth and pulmonary metastasis in a Lewis Lung Carcinoma (LLC) animal model. Methods For immunoblot analysis of COX-
Han Jae, Oh Young, Park Won, Pyo Hongryull   +3 more
doaj   +1 more source

Discrimination of Naturally-Occurring 2-Arylbenzofurans as Cyclooxygenase-2 Inhibitors: Insights into the Binding Mode and Enzymatic Inhibitory Activity

Biomolecules, 2020
2-arylbenzofuran-containing compounds are chemical entities that can be naturally produced by several organisms. A wide-range of activities is described for several compounds of this kind and they are, therefore, valuable moieties for a lead finding from
Ericsson Coy-Barrera
doaj   +1 more source

Tolerance to coxibs in patients with intolerance to non-steroidal anti-inflammatory drugs (NSAIDs) : a systematic structured review of the literature [PDF]

, 2007
Adverse events triggered by non-steroidal anti-inflammatory drugs (NSAIDs) are among the most common drug-related intolerance reactions in medicine; they are possibly related to inhibition of cyclooxygenase-1.
Weberschock, Tobias Bernd Bernd, Boehncke, Wolf-Henning, Tobias Bernd Weberschock, Sylke-Monina Müller, Sandra Boehncke, Müller, Sylke-Monina, Wolf-Henning Boehncke, Weberschock, Tobias Bernd, Boehncke, Sandra   +8 more
core   +1 more source

The role of cyclooxygenase-1 and cyclooxygenase-2 in lipopolysaccharide and interleukin-1 stimulated enterocyte prostanoid formation

Mediators of Inflammation, 1998
Lipopolysaccharide is an inflammatory agent and interleukin-1 is a cytokine. Their pro-inflammatory effects may be mediated by prostanoids produced by inducible cyclooxygenase-2.
W. E. Longo, L. J. Damore, J. E. Mazuski, G. S. Smith, N. Panesar, D. L. Kaminski   +5 more
doaj   +1 more source

Phosphatidylinositol transfer protein α regulates growth and apoptosis of NIH3T3 cells

Journal of Lipid Research, 2004
Mouse fibroblast cells overexpressing phosphatidylinositol transfer protein α [PI-TPα; sense PI-TPα (SPIα) cells] show a significantly increased rate of proliferation and an extreme resistance toward ultraviolet- or tumor necrosis factor-α-induced ...
Martijn Schenning, Claudia M. van Tiel, Daniëlle van Manen, Jord C. Stam, Barend M. Gadella, Karel W.A. Wirtz, Gerry T. Snoek   +6 more
doaj   +1 more source

Targeted Separation of COX-2 Inhibitor from Pterocephalus hookeri Using Preparative High-Performance Liquid Chromatography Directed by the Affinity Solid-Phase Extraction HPLC System

Molecules, 2021
Pterocephalus hookeri, as a kind of popular traditional Tibetan medicine, is reputed to treat inflammatory related diseases. In the present work, a cyclooxygenase-2 functionalized affinity solid-phase extraction HPLC system was developed and combined ...
Yunhe Zhu, Weidong Wang, Lei Jiang, Hui Tan, Zenggen Liu, Sirong Jiang, Yanduo Tao, Huaixiu Wen, Lijuan Mei   +8 more
doaj   +1 more source

Cyclooxygenase‐2 in oligodendroglial neoplasms [PDF]

Cancer, 2003
AbstractBACKGROUNDAlthough increased expression of cyclooxygenase‐2 (COX‐2) has been described in association with a variety of neoplasms, including tumors of astrocytic derivation, limited data are available on COX‐2 expression in oligodendrogliomas.METHODSThe current study retrospectively reviewed 53 oligodendrogliomas and 7 oligodendroglioma ...
Elias A, Castilla, Richard A, Prayson, Andrew A, Kanner, Lisa A, Rybicki, Raymond R, Tubbs, Michael A, Vogelbaum, Gene H, Barnett   +6 more
openaire   +2 more sources

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Cyclooxygenase-2 inhibitors: promise or peril?

Mediators of Inflammation, 2002
The discovery of two isoforms of the cyclooxygenase enzyme, COX-1 and COX-2, and the development of COX-2-specific inhibitors as anti-inflammatories and analgesics have offered great promise that the therapeutic benefits of NSAIDs could be optimized ...
Laurel J. Mengle-Gaw, Benjamin D. Schwartz   +1 more
doaj   +1 more source