Results 191 to 200 of about 113,056 (219)

A BSCB‐Penetrating Nanoplatform for Enhanced Luteolin Delivery in PRMT2‐Targeted Epigenetic Therapy of Spinal Cord Injury

Advanced Science, EarlyView.
In this work, MSN‐BO@LUT penetrates the blood‐spinal cord barrier for luteolin delivery in spinal cord injury. The nanodrug suppresses neuroinflammation and promotes functional recovery of the spinal cord. Mechanistically, luteolin targets protein arginine N‐methyltransferase (PRMT2) to decrease toll‐like receptor 4 (TLR4) methylation, thereby ...
Yixuan Wang, Bo Jin, Shipian Li, Qianxi Ouyang, Yu Xiao, Jiaxin Wen, Yehua Lai, Ping Wang, Yongjun Wang, Xuejun Cui, Weian Zhang, Min Yao   +11 more
wiley   +1 more source

Cyclooxygenase-dependent contribution to increased flow mediated dilatation following a week of repeated ischemic preconditioning. [PDF]

Eur J Appl Physiol
Thomas S, Murphy SR, AlSalahi SE, Junejo RT.   +3 more
europepmc   +1 more source

Lipoxin A 4 (LXA 4 ) for diabetic retinopathy (DR). [PDF]

Indian J Ophthalmol
Das UN.
europepmc   +1 more source

15- Deoxy-Δ12,14-prostaglandin J2 upregulates COX-2 expression and PGE₂ in mouse mesangial cells through a mechanism independent of PPARγ. [PDF]

Front Pharmacol
Yu B, Zhang Y, Hu Z, Fu X, Shen X, Rong X, Yang G.   +6 more
europepmc   +1 more source

A Narrative Review of Recent Developments in Aspirin Therapy After Desensitization in NSAIDs-Exacerbated Respiratory Disease. [PDF]

J Inflamm Res
Patel PK, Sharma Khatiwada A, Andrews PJ, Scadding GK, Pendolino AL.   +4 more
europepmc   +1 more source

Piperazine-Thiourea Hybrids as Novel Antiplatelet Agents Targeting COX-1: Synthesis, <i>in Vitro</i>, and <i>in Silico</i> Evaluation. [PDF]

ACS Omega
Pereira GRC, Viana GM, Huber MB, Rodrigues PS, Gonçalves ARSP, Sathler PC, Rodrigues CR, Abrahim-Vieira BA, Cabral LM.   +8 more
europepmc   +1 more source

Exploring the Anti-Inflammatory Potential of Saudi Propolis Through Phytochemical Characterization, Molecular Docking, and Dynamic Simulation. [PDF]

Pharmaceutics
Aati H, Alqahtani JH, Al-Taweel A, Aati SY.   +3 more
europepmc   +1 more source

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Cyclooxygenases: Structural, Cellular, and Molecular Biology

Annual Review of Biochemistry, 2000
R Michael Garavito, David Dewitt, D L Dewitt   +2 more
exaly