Results 201 to 210 of about 108,744 (262)
Real-World Trends in COX-2 Inhibitor Use in Pain Management. [PDF]
Hasoon J, Ezenekwe E, Orhurhu V.
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Elevated CHI3L1 and COX-2 levels correlate with menstrual pain severity in endometriosis. [PDF]
Rusly DK +6 more
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Neuroprotective Potential of <i>Hericium erinaceus</i> Through Modulation of Inflammatory Signaling in THP-1 Macrophages Under Low-Level Lead Exposure. [PDF]
Kupnicka P +6 more
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European Journal of Pharmacology, 1998
The anti-inflammatory activity of drugs more selective for cyclooxgenase isoform inhibition (cyclooxygenase 1, cyclooxygenase 2), were compared in rat carrageenin-induced pleurisy. Suppression of inflammation by cyclooxygenase 2-selective inhibitors, NS-398 (N-[-2-cyclohexyloxy]-4-nitrophenyl methanesulphonamide) and nimesulide (4-nitro-2-phenoxy ...
Derek W Gilroy +2 more
exaly +3 more sources
The anti-inflammatory activity of drugs more selective for cyclooxgenase isoform inhibition (cyclooxygenase 1, cyclooxygenase 2), were compared in rat carrageenin-induced pleurisy. Suppression of inflammation by cyclooxygenase 2-selective inhibitors, NS-398 (N-[-2-cyclohexyloxy]-4-nitrophenyl methanesulphonamide) and nimesulide (4-nitro-2-phenoxy ...
Derek W Gilroy +2 more
exaly +3 more sources
Cyclooxygenase‐independent actions of cyclooxygenase inhibitors
The FASEB Journal, 2001Several studies have demonstrated unequivocally that certain nonsteroidal anti‐inflammatory drugs (NSAIDs) such as sodium salicylate, sulindac, ibuprofen, and flurbiprofen cause anti‐inflammatory and antiproliferative effects independent of cyclooxy‐genase activity and prostaglandin synthesis inhibition.
I, Tegeder +2 more
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Current Protocols in Pharmacology, 1998
AbstractCyclooxygenase (COX, also known as prostaglandin H2 synthase, PGH2) is one of the most significant enzymes in pharmacology since COX inhibition is the mechanism of action of most nonsteroidal anti‐inflammatory drugs (NSAIDs). There are two forms: COX‐1 is a constitutive form of the enzyme that has been linked to the production of ...
J K, Gierse, C M, Koboldt
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AbstractCyclooxygenase (COX, also known as prostaglandin H2 synthase, PGH2) is one of the most significant enzymes in pharmacology since COX inhibition is the mechanism of action of most nonsteroidal anti‐inflammatory drugs (NSAIDs). There are two forms: COX‐1 is a constitutive form of the enzyme that has been linked to the production of ...
J K, Gierse, C M, Koboldt
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Pharmacogenomics of Cyclooxygenases
Pharmacogenomics, 2015Cyclooxygenases (COX-1 and COX-2) are key enzymes in several physiopathological processes. Many adverse drugs reactions to NSAIDs are attributable to COX-inhibition. The genes coding for these enzymes (PTGS1 and PTGS2) are highly variable, and variations in these genes may underlie the risk of developing, or the clinical evolution of, several diseases ...
José A G, Agúndez +3 more
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