Results 201 to 210 of about 109,753 (261)

Bioactive Potential and COX-2 Interaction of <i>Ajuga iva</i> (L.) Schreb. Hydroalcoholic Extract: Evidence from Experimental and Computational Studies. [PDF]

Molecules
Boutora Y, Boussekine S, Benslama O, Lekmine S, Mansouri N, Touzout N, Moussa H, Gacem R, Hfaiedh N, Nieto G.   +9 more
europepmc   +1 more source

Elevated CHI3L1 and COX-2 levels correlate with menstrual pain severity in endometriosis. [PDF]

SAGE Open Med
Rusly DK, Permadi W, Bayuaji H, Syam HH, Madjid TH, Ritonga MA, Rusda M.   +6 more
europepmc   +1 more source

Exploring the Antioxidant, Anti-Inflammatory and Skin-Enzyme Inhibitory Activities of Balkan Ethnomedicinal Herbs Through In Vitro and In Vivo Screening. [PDF]

Molecules
Kardasi Z, Dina E, Dajić-Stevanović Z, Ourailoglou D, Aligiannis N, Kourounakis AP.   +5 more
europepmc   +1 more source

Cyclooxygenase-1-Inhibition with Aspirin in Patients with Chronic Coronary Syndrome. [PDF]

TH Open
Friis KA, Pedersen OB, Larsen JB, Kristensen SD, Grove EL.   +4 more
europepmc   +1 more source

Synthesis of 4-Hydroxyphenylamino-Naphthoquinones as Paracetamol-Inspired Analogs: Chemical, In Silico, and Phenotypic Pharmacological Evaluation. [PDF]

Pharmaceutics
Quispe-Díaz IM, Rebaza-Rioja O, Lopez-Mercado S, Enriquez-Lara C, Asunción-Alvarez D, Ybañez-Julca RO, Mantilla-Rodríguez E, Gutiérrez-Alvarado WO, Pino-Rios R, Valderrama JA, Benites J.   +10 more
europepmc   +1 more source

Neuroprotective Potential of <i>Hericium erinaceus</i> Through Modulation of Inflammatory Signaling in THP-1 Macrophages Under Low-Level Lead Exposure. [PDF]

Int J Mol Sci
Kupnicka P, Szućko-Kociuba I, Trzeciak-Ryczek A, Ptak M, Piotrowska K, Kołodziejczak M, Baranowska-Bosiacka I.   +6 more
europepmc   +1 more source

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Differential effects of inhibitors of cyclooxygenase (cyclooxygenase 1 and cyclooxygenase 2) in acute inflammation

European Journal of Pharmacology, 1998
The anti-inflammatory activity of drugs more selective for cyclooxgenase isoform inhibition (cyclooxygenase 1, cyclooxygenase 2), were compared in rat carrageenin-induced pleurisy. Suppression of inflammation by cyclooxygenase 2-selective inhibitors, NS-398 (N-[-2-cyclohexyloxy]-4-nitrophenyl methanesulphonamide) and nimesulide (4-nitro-2-phenoxy ...
Derek Gilroy, Derek A Willoughby, A Tomlinson   +2 more
exaly   +3 more sources

Cyclooxygenase‐independent actions of cyclooxygenase inhibitors

The FASEB Journal, 2001
Several studies have demonstrated unequivocally that certain nonsteroidal anti‐inflammatory drugs (NSAIDs) such as sodium salicylate, sulindac, ibuprofen, and flurbiprofen cause anti‐inflammatory and antiproliferative effects independent of cyclooxy‐genase activity and prostaglandin synthesis inhibition.
I, Tegeder, J, Pfeilschifter, G, Geisslinger   +2 more
openaire   +2 more sources

Cyclooxygenase Assays

Current Protocols in Pharmacology, 1998
AbstractCyclooxygenase (COX, also known as prostaglandin H2 synthase, PGH2) is one of the most significant enzymes in pharmacology since COX inhibition is the mechanism of action of most nonsteroidal anti‐inflammatory drugs (NSAIDs). There are two forms: COX‐1 is a constitutive form of the enzyme that has been linked to the production of ...
J K, Gierse, C M, Koboldt
openaire   +2 more sources

Pharmacogenomics of Cyclooxygenases

Pharmacogenomics, 2015
Cyclooxygenases (COX-1 and COX-2) are key enzymes in several physiopathological processes. Many adverse drugs reactions to NSAIDs are attributable to COX-inhibition. The genes coding for these enzymes (PTGS1 and PTGS2) are highly variable, and variations in these genes may underlie the risk of developing, or the clinical evolution of, several diseases ...
José A G, Agúndez, Miguel, Blanca, José A, Cornejo-García, Elena, García-Martín   +3 more
openaire   +2 more sources