Solution‐processed high‐performance n‐type doped single‐crystalline organic semiconductor microwires (MWs) are reported. n‐Type dopants are located at the terrace edge of the MW, resulting in rapid doping and high interaction. n‐doped MWs show 5,000 times enhanced photosensitivity than evaporated films and high photo‐neuromorphic characteristics by ...
Yonghee Kim+5 more
wiley +1 more source
Correction to "hnRNPA2/B1 activates cyclooxygenase-2 and promotes tumor growth in human lung cancers". [PDF]
europepmc +1 more source
Synthesis of novel trans-2,3-dihydrofuran-pyrazole conjugates through molecular hybridization: molecular docking insights and evaluation of anti-inflammatory and anti-malarial activities. [PDF]
Kumari G+7 more
europepmc +1 more source
Self‐Adjusting Engineered Probiotic for Targeted Tumor Colonization and Local Therapeutics Delivery
Zou et al. developed an engineered strain of Escherichia coli Nissle 1917 with precise targeting abilities for colonization and on‐demand payload release. The engineered probiotic survives and embolizes tumors only in the presence of more than 5 mM L‐lactate. Furthermore, the introduction of an α‐hemolysin circuit enhances its anti‐tumor effect.
Zhen‐Ping Zou+8 more
wiley +1 more source
Cysteine-rich 61 mediates inflammation by the NF-κB/cyclooxygenase-2 pathway in RF/6A cells. [PDF]
Yeh PT, You JJ, Yang CH.
europepmc +1 more source
CRCFound: A Colorectal Cancer CT Image Foundation Model Based on Self‐Supervised Learning
CRCFound is a self‐supervised learning‐based CT image foundation model for colorectal cancer (CRC). Pretrained on 5137 unlabeled CRC CT images, it learns universal feature representations, enabling efficient adaptation to various clinical tasks. The model demonstrates outstanding performance and generalization across multiple diagnostic and prognosis ...
Jing Yang+13 more
wiley +1 more source
Exploring the Neuroprotective Properties of Celery (<i>Apium graveolens</i> Linn) Extract Against Amyloid-Beta Toxicity and Enzymes Associated with Alzheimer's Disease. [PDF]
Mohamud Dirie L+3 more
europepmc +1 more source
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song+9 more
wiley +1 more source
Expression of Cyclooxygenase-1 and Cyclooxygenase-2 in Human Breast Cancer [PDF]
Daniel Hwang+3 more
openalex +1 more source
Midkine (MDK) is a mediator of the interaction between pancreatic cancer and beta cells. MDK, which originated from pancreatic ductal adenocarcinoma cells, exerted deleterious effects on paraneoplastic beta cells by binding to the SDC4 receptor on the beta cell surface and subsequently downregulating the Ras signaling pathway, thereby impairing insulin
Zengyu Feng+7 more
wiley +1 more source