Results 221 to 230 of about 21,811,854 (372)

The selective cyclooxygenase-2 inhibitor NS398 ameliorates cisplatin-induced impairments in mitochondrial and cognitive function. [PDF]

Front Mol Neurosci, 2023
Rashid MA, Tang JJ, Yoo KH, Corujo-Ramirez A, Oliveros A, Kim SH, Ullah F, Altawell R, Hawse JR, Cole PD, Jang MH.   +10 more
europepmc   +1 more source

Eosinophils‐Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF‐β Pathway Mediated by Anxa1 Binding

Advanced Science, EarlyView.
Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen, Yuwei Zhou, Wenxiu Yuan, Yanjing Ou, Hanyu Lin, Kaixun He, Xueshen Qian, Huachen Chen, Chengchaozi Wang, Jie Lu, Weiping Chen, Dexiong Li, Jiang Chen   +12 more
wiley   +1 more source

Differential Regulation of Cyclooxygenases 1 and 2 by Interleukin-1β, Tumor Necrosis Factor-α, and Transforming Growth Factor-β1 in Human Lung Fibroblasts

, 1998
Arturo Díaz, Kenneth P. Chepenik, Joseph H. Korn, Anthony M. Reginato, Sergio A. Jiménez   +4 more
openalex   +1 more source

Cyclooxygenase-2 (cox-2) in the thick ascending limb: regulation and function. [PDF]

, 1999
Nicholas R. Ferreri
openalex   +1 more source

Expression of cyclooxygenase-2 (COX-2) in epithelial ovarian cancers in an Indigenous African population of Kano, Nigeria. [PDF]

Ecancermedicalscience
Abdulrazaq JA, Abdullahi M, Chim NP, Samuel RK.   +3 more
europepmc   +1 more source

Non‐Invasive Tumor Budding Evaluation and Correlation with Treatment Response in Bladder Cancer: A Multi‐Center Cohort Study

Advanced Science, EarlyView.
This study introduces a deep learning model that predicts tumor budding (TB) status in bladder cancer through the analysis of CT images. The model effectively identifies patients with high TB status, correlating with poorer prognosis and reduced responsiveness to neoadjuvant chemoimmunotherapy. This tool offers significant potential to inform prognosis
Xiaoyang Li, Chen Zou, Chunhui Wang, Cheng Chang, Yi Lin, Shuai Liang, Haoran Zheng, Libo Liu, Kai Deng, Lin Zhang, Bohao Liu, Mingchao Gao, Peicong Cai, Jianwen Lao, Longhao Xu, Daqin Wu, Xiao Zhao, Xiao Wu, Xinyuan Li, Yun Luo, Wenlong Zhong, Tianxin Lin   +21 more
wiley   +1 more source

Exploring the Anti-inflammatory Potential of Novel Chrysin Derivatives through Cyclooxygenase-2 Inhibition. [PDF]

ACS Omega
Lee Y, Gu EJ, Song HY, Yoo BG, Park JE, Jeon J, Byun EB.   +6 more
europepmc   +1 more source

Targeted STING Activation Using Modified Ultrasound‐Responsive Microbubbles Enhances Immune Checkpoint Blockade Against Melanoma

Advanced Science, EarlyView.
This study explores the use of ultrasound contrast agents loaded with Stimulator of Interferon Genes (STING) agonists as an approach to activate the body's immune system against cancer. Termed Microbubble‐assisted UltraSound‐guided Immunotherapy of Cancer (MUSIC), this strategy effectively inhibits tumor growth and improves survival in mouse models of ...
Sina Khorsandi, Kristin Huntoon, Yifan Wang, Adam Woodward, Abin Antony, Connor Endsley, Nazia Hafeez, Jared L. Edwards, Nicole McCuen, Prasanna G. Alluri, Betty Y.S. Kim, Wen Jiang, Jacques Lux   +12 more
wiley   +1 more source

The Expression of Cyclooxygenase-2 in Cervical Intraepithelial Neoplasia and Cervical Cancer. [PDF]

Cureus
Shaik N, Nerune SM, Patil VS, Jawalkar S.   +3 more
europepmc   +1 more source

Decreased cyclooxygenase-2 associated with impaired megakaryopoiesis and thrombopoiesis in primary immune thrombocytopenia. [PDF]

J Transl Med, 2023
Zhuang X, Xu P, Ou Y, Shao X, Li Y, Ma Y, Qin S, Hua F, Zhan Y, Ji L, Qiao T, Chen H, Cheng Y.   +12 more
europepmc   +1 more source