Results 321 to 330 of about 21,811,854 (372)

SNORA74A Drives Self‐Renewal of Liver Cancer Stem Cells and Hepatocarcinogenesis Through Activation of Notch3 Signaling

open access: yesAdvanced Science, EarlyView.
Abstract Liver cancer stem cells (CSCs) account for tumor initiation, heterogeneity and therapy resistance. However, the role of small nucleolar RNAs (snoRNAs) in the regulation of liver CSCs remains largely unclear. Here, this work identifies a conserved H/ACA box snoRNA SNORA74A which is highly expressed in liver CSCs.
Ziheng Zhou   +12 more
wiley   +1 more source

An in vivo drug screen in zebrafish reveals that cyclooxygenase 2-derived prostaglandin D2 promotes spinal cord neurogenesis. [PDF]

open access: yesCell Prolif
González-Llera L   +4 more
europepmc   +1 more source

In utero exposure to maternal diabetes exacerbates dietary sodium intake-induced endothelial dysfunction by activating cyclooxygenase 2-derived prostanoids.

open access: yesAm J Physiol Endocrinol Metab
Costa RM   +7 more
europepmc   +1 more source

Cyclooxygenase‐2 in cancer: A review

Journal of Cellular Physiology, 2018
AbstractCyclooxygenase‐2 (COX‐2) is frequently expressed in many types of cancers exerting a pleiotropic and multifaceted role in genesis or promotion of carcinogenesis and cancer cell resistance to chemo‐ and radiotherapy. COX‐2 is released by cancer‐associated fibroblasts (CAFs), macrophage type 2 (M2) cells, and cancer cells to the tumor ...
Nasser Hashemi Goradel   +4 more
openaire   +4 more sources

Cyclooxygenase-2 and atherosclerosis

Current Opinion in Lipidology, 2002
Cyclooxygenase regulates the production of eicosanoids, which modulate physiologic processes in the vessel wall contributing to atherosclerosis and thrombosis, including platelet aggregation, control of vascular tone, and the local inflammatory response.
MacRae F. Linton, Sergio Fazio
openaire   +4 more sources

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