Results 31 to 40 of about 587,828 (75)

InhibiDistilbert: Knowledge Distillation for a ReLU and Addition-based Transformer [PDF]

arXiv
This work explores optimizing transformer-based language models by integrating model compression techniques with inhibitor attention, a novel alternative attention mechanism. Inhibitor attention employs Manhattan distances and ReLU activations instead of the matrix multiplications and softmax activation of the conventional scaled dot-product attention.
arxiv  

Monocytic myeloid-derived suppressor cells reflect tuberculosis severity and are influenced by cyclooxygenase-2 inhibitors. [PDF]

J Leukoc Biol, 2021
Jøntvedt Jørgensen M, Jenum S, Tonby K, Mortensen R, Walzl G, Du Plessis N, Dyrhol-Riise AM.   +6 more
europepmc   +1 more source

Pulmonaria obscura and Pulmonaria officinalis Extracts as Mitigators of Peroxynitrite-Induced Oxidative Stress and Cyclooxygenase-2 Inhibitors-In Vitro and In Silico Studies. [PDF]

Molecules, 2021
Krzyżanowska-Kowalczyk J, Kowalczyk M, Ponczek MB, Pecio Ł, Nowak P, Kolodziejczyk-Czepas J.   +5 more
europepmc   +1 more source

Prediction of Binding Affinity for ErbB Inhibitors Using Deep Neural Network Model with Morgan Fingerprints as Features [PDF]

arXiv
The ErbB receptor family, including EGFR and HER2, plays a crucial role in cell growth and survival and is associated with the progression of various cancers such as breast and lung cancer. In this study, we developed a deep learning model to predict the binding affinity of ErbB inhibitors using molecular fingerprints derived from SMILES ...
arxiv  

Design, synthesis, biological assessment and in silico ADME prediction of new 2-(4-(methylsulfonyl) phenyl) benzimidazoles as selective cyclooxygenase-2 inhibitors. [PDF]

RSC Adv, 2021
Badawy MAS, Abdelall EKA, El-Nahass ES, Abdellatif KRA, Abdel-Rahman HM.   +4 more
europepmc   +1 more source

Safety and potential efficacy of cyclooxygenase-2 inhibitors in coronavirus disease 2019. [PDF]

Clin Transl Immunology, 2020
Ong SWX, Tan WYT, Chan YH, Fong SW, Renia L, Ng LF, Leo YS, Lye DC, Young BE.   +8 more
europepmc   +1 more source

Preemptive analgesia using selective cyclooxygenase-2 inhibitors alleviates postoperative pain in patients undergoing total knee arthroplasty: A protocol for PRISMA guided meta-analysis of randomized controlled trials. [PDF]

Medicine (Baltimore), 2021
Wang C, Fu H, Wang J, Huang F, Cao X.
europepmc   +1 more source

Identification of New Rofecoxib-Based Cyclooxygenase-2 Inhibitors: A Bioinformatics Approach. [PDF]

Pharmaceuticals (Basel), 2020
Leão RP, Cruz JV, da Costa GV, Cruz JN, Ferreira EFB, Silva RC, de Lima LR, Borges RS, Dos Santos GB, Santos CBR.   +9 more
europepmc   +1 more source

Harmaline Analogs as Substrate-Selective Cyclooxygenase-2 Inhibitors. [PDF]

ACS Med Chem Lett, 2020
Uddin MJ, Xu S, Crews BC, Aleem AM, Ghebreselasie K, Banerjee S, Marnett LJ.   +6 more
europepmc   +1 more source

Discovery of Novel Pyridazine-Based Cyclooxygenase-2 Inhibitors with a Promising Gastric Safety Profile. [PDF]

Molecules, 2020
Khan A, Diwan A, Thabet HK, Imran M, Bakht MA.   +4 more
europepmc   +1 more source