Results 21 to 30 of about 58,086 (152)

Targeted Separation of COX-2 Inhibitor from Pterocephalus hookeri Using Preparative High-Performance Liquid Chromatography Directed by the Affinity Solid-Phase Extraction HPLC System

Molecules, 2021
Pterocephalus hookeri, as a kind of popular traditional Tibetan medicine, is reputed to treat inflammatory related diseases. In the present work, a cyclooxygenase-2 functionalized affinity solid-phase extraction HPLC system was developed and combined ...
Yunhe Zhu, Weidong Wang, Lei Jiang, Hui Tan, Zenggen Liu, Sirong Jiang, Yanduo Tao, Huaixiu Wen, Lijuan Mei   +8 more
doaj   +1 more source

Clinical experience with cyclooxygenase-2 inhibitors [PDF]

Rheumatology, 2002
Rheumatoid arthritis (RA) and osteoarthritis (OA) are chronic conditions requiring long-term therapy for pain relief. Currently prescribed non-steroidal anti-inflammatory drugs (NSAIDs) provide symptomatic efficacy, but are frequently associated with gastrointestinal (GI) toxicities such as dyspepsia and ulcerations.
openaire   +2 more sources

Cyclooxygenase-2 (COX-2) inhibitors: future therapeutic strategies for epilepsy management

Journal of Neuroinflammation, 2019
Epilepsy, a common multifactorial neurological disease, affects about 69 million people worldwide constituting nearly 1% of the world population.
Chitra Rawat, Samiksha Kukal, Ujjwal Ranjan Dahiya, Ritushree Kukreti   +3 more
doaj   +1 more source

The role of cyclooxygenase-1 and cyclooxygenase-2 in lipopolysaccharide and interleukin-1 stimulated enterocyte prostanoid formation

Mediators of Inflammation, 1998
Lipopolysaccharide is an inflammatory agent and interleukin-1 is a cytokine. Their pro-inflammatory effects may be mediated by prostanoids produced by inducible cyclooxygenase-2.
W. E. Longo, L. J. Damore, J. E. Mazuski, G. S. Smith, N. Panesar, D. L. Kaminski   +5 more
doaj   +1 more source

Individualized ibuprofen treatment using serial B-type natriuretic peptide measurement for symptomatic patent ductus arteriosus in very preterm infants [PDF]

Korean Journal of Pediatrics, 2017
PurposePlasma level of B-type natriuretic peptide (BNP), an emerging, sensitive, and specific biomarker of hemodynamically significant patent ductus arteriosus (PDA), rapidly decreases in infants receiving cyclooxygenase inhibitors for ductal closure. We
Jeonghee Shin, Eun Hee Lee, Jee Hyun Lee, Byung Min Choi, Young Sook Hong   +4 more
doaj   +1 more source

Antimetastatic activity of a cyclooxygenase-2 inhibitor [PDF]

British Journal of Cancer, 2004
Cyclooxygenase-2 (COX-2) expression is increased in breast cancer and surgery has been shown to increase the growth of metastatic tumours. We investigated the effect of selective COX-2 inhibition on the growth of metastases in either an experimental metastasis model or following excision of a murine primary breast tumour.
Roche-Nagle, G, Connolly, E M, Eng, M, Bouchier-Hayes, D J, Harmey, J H   +4 more
openaire   +2 more sources

Nonsteroidal anti-inflammatory drugs and acetaminophen ameliorate muscular mechanical hyperalgesia developed after lengthening contractions via cyclooxygenase-2 independent mechanisms in rats.

PLoS ONE, 2019
Nonsteroidal anti-inflammatory drugs and acetaminophen are cyclooxygenase inhibitors commonly used as symptomatic medicines for myofascial pain syndrome.
Tetsuhiro Shimodaira, Shigeo Mikoshiba, Toru Taguchi   +2 more
doaj   +1 more source

In vitro and In Silico Studies on Curcumin and Its Analogues as Dual Inhibitors for cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2)

Journal of Mathematical and Fundamental Sciences, 2013
Curcumin has been widely reported as an anti-inflammatory agent isolated from the plant Curcuma longa L. (turmeric). This anti-inflammatory activity was associated with the ability of this compound to inhibit the activity of both cyclooxygenase-1 (COX-1)
Nunung Yuniarti, Perdana Adhi Nugroho, Aditya Asyhar, Sardjiman Sardjiman, Zullies Ikawati, Enade Perdana Istyastono   +5 more
doaj   +1 more source

Comparison of the clinical efficacy of celebrex and celecoxib for pain relief after periodontal surgeries

Journal of Craniomaxillofacial Research, 2019
Background: Currently one of the most common problems in dentistry is effective pain management after dental surgeries. Celecoxib is the only specific COX-2 inhibitor used in Iran.
Mohammad Reza Naseh, Masoumeh Mirkeshavarz, Zahra Jafary   +2 more
doaj   +1 more source

Subcutaneous emphysema of the face in Sina hospital: A case report

Journal of Craniomaxillofacial Research, 2019
Subcutaneous emphysema of the face is an uncommon complication caused by dental procedures such as curettage, root canal treatment, extraction, restorative treatment and dental instruments like air-water syringe and hand piece.
Farnoosh Mohammadi, Bahman Seraj, Sajjad Baber   +2 more
doaj   +1 more source