Results 1 to 10 of about 114,365 (325)

Effect of cyclooxygenase inhibitors on gentamicin-induced nephrotoxicity in rats [PDF]

open access: goldBrazilian Journal of Medical and Biological Research, 2004
The frequent use of nonsteroidal anti-inflammatory drugs (NSAID) in combination with gentamicin poses the additional risk of nephrotoxic renal failure.
Hosaka E.M.   +3 more
doaj   +2 more sources

Dual Effects of Cyclooxygenase Inhibitors in Combination With CD19.CAR-T Cell Immunotherapy [PDF]

open access: yesFrontiers in Immunology, 2021
Chimeric antigen receptor T (CAR-T) cells targeting CD19 came into clinical practice for the treatment of B cell lymphoma in 2018. However, patients being treated for B cell lymphoma often suffer from comorbidities such as chronic pain, cardiovascular ...
Mingya Yang   +24 more
doaj   +2 more sources

Stimulatory Action of Cyclooxygenase Inhibitors on Hematopoiesis: A Review [PDF]

open access: yesMolecules, 2012
The presented review summarizes experimental data obtained with a mouse model when investigating the relationship between inhibition of prostaglandin production and hematopoiesis.
Lenka Weiterová   +4 more
doaj   +2 more sources

The role of cyclooxygenase inhibitors in lipopolysaccharide-induced hypophagia in chicken

open access: goldCzech Journal of Animal Science, 2015
Previous studies showed that cyclooxygenase 1 (COX) enzyme has an important role in lipopolysaccharide (LPS)-induced hypophagia in mammals but the effect of COX on LPS-induced hypophagia has not been studied in avian species.
M. Zendehdel   +3 more
doaj   +2 more sources

Indole Derivatives as Cyclooxygenase Inhibitors: Synthesis, Biological Evaluation and Docking Studies [PDF]

open access: yesMolecules, 2018
A new series of 2-(5-methoxy-2-methyl-1H-indol-3-yl)-N′-[(E)-(substituted phenyl) methylidene] acetohydrazide derivatives (S1–S18) were synthesized and evaluated for their anti-inflammatory activity, analgesic activity, ulcerogenic activity ...
Mashooq Ahmad Bhat   +6 more
doaj   +2 more sources

Docking studies of some pyrazole containing compounds in the cyclooxygenase-2 active site [PDF]

open access: yesArhiv za farmaciju, 2023
Whereas nonselective nonsteroidal anti-inflammatory drugs, such as aspirin, ibuprofen and diclofenac, inhibit both cyclooxygenase-1 and cyclooxigenase-2 enzymes, selective inhibitors target cyclooxygenase-2, which is overexpressed in inflammation, but ...
Savić Jelena   +3 more
doaj  

Effects of Cyclooxygenase Inhibitors on Apoptotic Neuroretinal Cells

open access: yesBiomarker Insights, 2008
Glaucoma is characterized by a loss of retinal ganglion cells (RGC) which is associated with a decrease of visual function. Neuroprotective agents as a new therapeutic strategy could prevent the remaining neurons from apoptotic cell death.
Anja-Kristina Brust   +4 more
doaj   +2 more sources

Macrostachyols A-D, oligostilbenes from Gnetum macrostachyum inhibited in vitro human platelet aggregation [PDF]

open access: yesJournal of HerbMed Pharmacology, 2021
Introduction: Gnetum macrostachyum is a known Thai medicinal plant as a source of bioactive oligostilbenes, which possess platelet inhibitory activities.
Serm Surapinit, Nuttakorn Baisaeng
doaj   +1 more source

Treatment with paracetamol, ketorolac or etoricoxib did not hinder alveolar bone healing: a histometric study in rats

open access: yesJournal of Applied Oral Science, 2010
Prostaglandins control osteoblastic and osteoclastic function under physiological or pathological conditions and are important modulators of the bone healing process.
Ricardo Nogueira Fracon   +3 more
doaj   +1 more source

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