Results 11 to 20 of about 2,867,692 (324)
Conjugation of cisplatin analogues and cyclooxygenase inhibitors to overcome cisplatin resistance. [PDF]
ChemMedChem, 2015 Neumann W +7 more
europepmc +2 more sources
Cyclooxygenase Inhibitors and the Antiplatelet Effects of Aspirin
New England Journal of Medicine, 2001 Patients with arthritis and vascular disease may receive both low-dose aspirin and other nonsteroidal antiinflammatory drugs. We therefore investigated potential interactions between aspirin and commonly prescribed arthritis therapiesWe administered the following combinations of drugs for six days: aspirin (81 mg every morning) two hours before ...
Susan DeMarco +7 more
openaire +4 more sources
Conjugates of cisplatin and cyclooxygenase inhibitors as potent antitumor agents overcoming cisplatin resistance. [PDF]
ChemMedChem, 2014 Neumann W +3 more
europepmc +2 more sources
Cyclooxygenase (cox) Inhibitors and the Intestine [PDF]
Journal of Veterinary Internal Medicine, 2007 Nonsteroidal anti‐inflammatory drugs (NSAIDs) have long been used for the treatment of pain and inflammation because of their inhibitory effects on cyclooxygenase (COX). For almost as long as NSAIDs have been in use, multiple adverse effects have been noted.
Anthony T. Blikslager +2 more
openaire +3 more sources
Docking studies of some pyrazole containing compounds in the cyclooxygenase-2 active site [PDF]
Arhiv za farmaciju, 2023 Whereas nonselective nonsteroidal anti-inflammatory drugs, such as aspirin, ibuprofen and diclofenac, inhibit both cyclooxygenase-1 and cyclooxigenase-2 enzymes, selective inhibitors target cyclooxygenase-2, which is overexpressed in inflammation, but ...
Savić Jelena +3 more
doaj
Macrostachyols A-D, oligostilbenes from Gnetum macrostachyum inhibited in vitro human platelet aggregation [PDF]
Journal of HerbMed Pharmacology, 2021 Introduction: Gnetum macrostachyum is a known Thai medicinal plant as a source of bioactive oligostilbenes, which possess platelet inhibitory activities.
Serm Surapinit, Nuttakorn Baisaeng
doaj +1 more source
Update on Cyclooxygenase-2 Inhibitors [PDF]
Clinical Journal of the American Society of Nephrology, 2006 Nonsteroidal anti-inflammatory drugs represent the most commonly used medications for the treatment of pain and inflammation, but numerous well-described side effects can limit their use. Cyclooxygenase-2 (COX-2) inhibitors were initially touted as a therapeutic strategy to avoid not only the gastrointestinal but also the renal and cardiovascular side ...
Matthew D. Breyer, Raymond C. Harris
openaire +3 more sources
Effects of Cyclooxygenase Inhibitors on Apoptotic Neuroretinal Cells
Biomarker Insights, 2008 Glaucoma is characterized by a loss of retinal ganglion cells (RGC) which is associated with a decrease of visual function. Neuroprotective agents as a new therapeutic strategy could prevent the remaining neurons from apoptotic cell death.
Anja-Kristina Brust +4 more
doaj +2 more sources
Journal of Applied Oral Science, 2010 Prostaglandins control osteoblastic and osteoclastic function under physiological or pathological conditions and are important modulators of the bone healing process.
Ricardo Nogueira Fracon +3 more
doaj +1 more source
The overexpression of COX 2 in Wilms’ tumor [PDF]
Reviews in Clinical Medicine, 2014 Cyclooxygenase 2 has become an important pharmacological target in anticancer therapy due to the over expression of COX 2 in pathological conditions. Wilms’ tumor is a common kidney cancer in children which has shown an increase in COX 2 enzyme level ...
Sara Hashemi
doaj +3 more sources