Results 21 to 30 of about 10,845 (167)
Acta Crystallographica Section E: Crystallographic Communications, 2019 The title compound, C18H18F2N2O3, crystallizes with two independent molecules (A and B) in the asymmetric unit. They differ essentially in the orientation of the pyridine ring with respect to the benzene ring; these two rings are inclined to each other ...
G. Artheswari +2 more
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Gold-catalyzed ethylene cyclopropanation
Beilstein Journal of Organic Chemistry, 2019 Ethylene can be directly converted into ethyl 1-cyclopropylcarboxylate upon reaction with ethyl diazoacetate (N2CHCO2Et, EDA) in the presence of catalytic amounts of IPrAuCl/NaBArF4 (IPr = 1,3-bis(2,6-diisopropylphenyl)imidazole-2-ylidene; BArF4 ...
Silvia G. Rull +2 more
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Synthesis of 2-[2-(Ethoxymethoxy)phenyl]spiro[cyclopropane-1,2′-indene]-1′,3′-dione
Molbank, 2023 An 1,3-indanedione-derived donor–acceptor cyclopropane, bearing the ethoxymethyl-protected phenolic group at the ortho-position of the donor aryl substituent, has been synthesized using a reaction sequence involving the Knoevenagel condensation of 1,3 ...
Olga A. Ivanova +6 more
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Electrogenerated base-promoted cyclopropanation using alkyl 2-chloroacetates
Beilstein Journal of Organic Chemistry, 2022 The electrochemical reduction conditions of the reaction of alkyl 2-chloroacetates in Bu4NBr/DMF using a divided cell equipped with Pt electrodes to produce the corresponding cyclopropane derivatives in moderate yields were discovered.
Kouichi Matsumoto +6 more
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Advanced Science, EarlyView.We have developed a Pd‐catalyzed oxidative cyclopropanation of 1,n‐enynes employing cyclic diacyl peroxides as bifunctional reagents that serve as both tether‐tunable oxidants and spatially controlled dicarboxylate anions. ABSTRACT Bicyclo[n.1.0]alkanes are highly valuable scaffolds in drug discovery and synthetic chemistry.
Ting Yuan, Lei Shi
wiley +1 more source
IUCrData, 2016 In the racemic title compound, C14H16O3, the dihedral angle formed by the mean planes of the cyclopropane and benzene rings is 5.0 (2)°. In the crystal, a pair of weak C—H...O hydrogen bonds connect two molecules related by a twofold rotation axis, thus ...
Alan J. Lough +2 more
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The Search for Biologically Active Compounds in the Series of N-ethoxyethylpiperidine Derivatives
Eurasian Chemico-Technological Journal, 2019 With the aim to introduce fragment of cyclopropane and fragments of p-, m-, o-fluorophenyls into the structures of N-ethoxyethylpiperidines, acylation of oxime and phenylacetylenic alcohol of 1-(2-ethoxyethyl)-4-ketopiperidine by ...
U. B. Issayeva +5 more
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Synthesis of a novel chemotype via sequential metal-catalyzed cycloisomerizations
Beilstein Journal of Organic Chemistry, 2012 Sequential cycloisomerizations of diynyl o-benzaldehyde substrates to access novel polycyclic cyclopropanes are reported. The reaction sequence involves initial Cu(I)-mediated cycloisomerization/nucleophilic addition to an isochromene followed by ...
Bo Leng +4 more
doaj +1 more source
Chemistry – A European Journal, EarlyView.The synthesis of 2‐methyl propellane and its conversion to various 1,2‐ and 1,2,3‐di‐ and trisubstituted bicyclopentanes is reported. Abstract Bicyclo[1.1.1]pentanes (BCPs) have emerged as isosteric replacements for mono‐ and para‐substituted benzene rings in medicinal and materials applications, involving substitution at the BCP bridgehead (1,3 ...
Sean R. Verschaeve +4 more
wiley +1 more source
The Diarylprolinol Silyl Ethers: After 20 Years Still Opening New Doors in Asymmetric Catalysis
Angewandte Chemie, Volume 138, Issue 11, 9 March 2026.Catalysis Rules! The year 2025 marks the 20th anniversary of diarylprolinol silyl ethers in asymmetric organocatalysis. During the first decade after their discovery, these catalysts have been established as one of the most versatile tools in aminocatalysis. Although now considered mature, recent years have witnessed renewed innovation.
Enrico Marcantonio +2 more
wiley +2 more sources