Results 11 to 20 of about 21,746 (290)

Photochemical Allylation of Aldehydes or Alkanes with Vinyl Cyclopropanes

ChemistryEurope
Vinyl cyclopropanes are useful linchpins for the synthesis of more complex scaffolds. In this work, we present an acylation or alkylation protocol of donor–acceptor vinyl cyclopropanes, employing tetra‐n‐butylammonium decatungstate as the photocatalyst ...
Naya A. Stini, Christoforos G. Kokotos
doaj   +2 more sources

Copper‐Catalyzed Enantio‐ and Diastereoselective Addition of Silicon Nucleophiles to 3,3‐Disubstituted Cyclopropenes [PDF]

, 2019
A highly stereocontrolled syn‐addition of silicon nucleophiles across cyclopropenes with two different geminal substituents at C3 is reported. Diastereomeric ratios are excellent throughout (d.r.≥98:2) and enantiomeric excesses usually higher than 90 ...
Oestreich, Martin, Zhang, Liangliang
core   +1 more source

The Solubility Studies and the Complexation Mechanism Investigations of Biologically Active Spiro[cyclopropane-1,3′-oxindoles] with β-Cyclodextrins

Pharmaceutics, 2023
In this work, we first improved the aqueous solubility of biologically active spiro[cyclopropane-1,3′-oxindoles] (SCOs) via their complexation with different β-cyclodextrins (β-CDs) and proposed a possible mechanism of the complex formation.
Anna A. Kravtsova, Anna A. Skuredina, Alexander S. Malyshev, Irina M. Le-Deygen, Elena V. Kudryashova, Ekaterina M. Budynina   +5 more
doaj   +1 more source

Green and Facile Synthesis of Spirocyclopentanes Through NaOH-Promoted Chemo- and Diastereo-Selective (3 + 2) Cycloaddition Reactions of Activated Cyclopropanes and Enamides

Frontiers in Chemistry, 2020
A chemo- and diastereo-selective (3 + 2) cycloaddition reacition between Donor-Acceptor (D-A) cyclopropanes and α,β-unsaturated enamides is developed for efficient access to spiro(cyclopentane-1,3'-indoline) derivatives.
Xun Zhu, Dingwu Pan, Chengli Mou, Bo Zhou, Lutai Pan, Zhichao Jin   +5 more
doaj   +1 more source

Synthetic Applications and Methodological Developments of Donor-Acceptor Cyclopropanes and Related Compounds [PDF]

, 2016
Donor-acceptor cyclopropanes are convenient precursors to reactive and versatile 1,3-dipoles, and have found application in the synthesis of a variety of carbo- and heterocyclic scaffolds.
O'Connor, Nicholas R., Stoltz, Brian M., Wood, John L.   +2 more
core   +1 more source

Copper, Boron and Vinyl Epoxides: from 1,4-Diols to Cyclopropylboronates

CHIMIA, 2020
Herein we describe the reactivity found between vinyl epoxides and catalytically generated copper-boryl complexes. By tuning the substituents of the alkene and/or the reaction conditions, 1,4-diols, allylic alcohols or cyclopropylboronates can be ...
Luis Novoa, Laura Trulli, Alejando Parra, Mariola Tortosa   +3 more
doaj   +1 more source

Preparation of Chiral Enantioenriched Densely Substituted Cyclopropyl Azoles, Amines, and Ethers via Formal S_N2′ Substitution of Bromocylopropanes

Molecules, 2022
Enantiomerically enriched cyclopropyl ethers, amines, and cyclopropylazole derivatives possessing three stereogenic carbon atoms in a small cycle are obtained via the diastereoselective, formal nucleophilic substitution of chiral, non-racemic ...
Hillary Straub, Pavel Ryabchuk, Marina Rubina, Michael Rubin   +3 more
doaj   +1 more source

Synthesis and reactions of donor cyclopropanes: efficient routes to cis- and trans-tetrahydrofurans [PDF]

, 2015
A detailed study on the synthesis and reactions of silylmethylcyclopropanes is reported. In their simplest form, these donor-only cyclopropanes undergo Lewis acid promoted reaction to give either cis- or trans-tetrahydrofurans, with the selectivity being
Adrian P. Dobbs, Affo, Alali, Barbero, Bermejo, Calter, Campbell, Cavitt, Chio, Colin, Coulson, Dobbs, Dobbs, Dobbs, Dobbs, Dobbs, Dobbs, Dobbs, Dunn, Fleming, Fleming, Fuchibe, Grover, Hattori, Jonathan Dunn, Jones, Karadeoltan, Knolker, Kojima, Lewis, Li, Liaw, Mironov, Muchowski, Pohlhaus, Pornet, Rawson, Reddy, Reissig, Reissig, Salvador, Salvador, Schneider, Soderquist, Spurr, Tang, Witiak, Yu, Zeng   +48 more
core   +1 more source

Photoredox-catalyzed oxo-amination of aryl cyclopropanes

Nature Communications, 2019
The ring-opening and functionalization of electronically unbiased cyclopropanes is highly challenging to achieve in a regioselective fashion. Here, the authors report a mild photoredox-coupled oxoamination of electronically unactivated aryl cyclopropanes
Liang Ge, Ding-Xing Wang, Renyi Xing, Di Ma, Patrick J. Walsh, Chao Feng   +5 more
doaj   +1 more source

A Study of Palladium Catalyzed Intra/Intermolecular Cascade Cross Coupling/Cyclizations Involving Bicyclopropylidene

Molecules, 2014
The compounds [3-(2-Bromocyclohex-2-enyloxy)prop-1-ynyl]-tert-butyl-dimethylsilane 3, [4-(2-bromocyclohex-2-en-1-yloxy)but-2-yn-1-yloxy]tert-butyldimethylsilane 5 and dimethyl 2-(2-bromocyclohex-2-enyl)-2-(3-(tert-butyldimethylsilanyl)prop-2-ynyl ...
Aydin Demircan
doaj   +1 more source