Results 11 to 20 of about 19,882 (280)

Transforming cyclopropanes to enamides via σ-C–C bond eliminative borylation [PDF]

Nature Communications
Recent strides in C–H borylation have significantly expanded our toolkit for the preparation of organoboronates. Nevertheless, avenues alternative to obtain these compounds via σ-C–C cleavage, thereby facilitating molecular scaffold editing, remain ...
Shuyu Kang, Jiahang Lv, Tianhang Wang, Bingcheng Wu, Minyan Wang, Zhuangzhi Shi   +5 more
doaj   +2 more sources

Dirhodium‐Catalyzed Enantioselective Synthesis of Difluoromethylated Cyclopropanes via Enyne Cycloisomerization [PDF]

Advanced Science
(Difluoromethylated cyclopropane represents an important motif, which is widely found in bioactive and functional molecules. Despite significant progress in modern chemistry, the atom‐economic and enantioselective synthesis of difluoromethylated ...
Chuntao Wang, Dong Zhu, Rui Wu, Shifa Zhu   +3 more
doaj   +2 more sources

Chemo-, regio- and enantioselective hydroformylation of trisubstituted cyclopropenes: access to chiral quaternary cyclopropanes [PDF]

Nature Communications
Catalytic asymmetric synthesis of polysubstituted chiral cyclopropane presents a significant challenge in organic synthesis due to the difficulty in enantioselective control.
Shuailong Li, Dequan Zhang, Aiswarya Purushothaman, Hui Lv, Shilpa Shilpa, Raghavan B. Sunoj, Xiuxiu Li, Xumu Zhang   +7 more
doaj   +2 more sources

Highly efficient construction of angular polycycles [PDF]

Nature Communications
Angular tricyclic and polycyclic skeletons feature typical cores in an intriguing type of natural products. We herein report the Lewis acids-catalyzed dearomative (3 + 2) cycloadditions of donor-acceptor cyclopropanes with benzene ring, by which ...
Yi Sun, Xiaobing Huang, Jun Ren, Zhongwen Wang   +3 more
doaj   +2 more sources

Nitrogen Insertion via Asymmetric Condensation and Chirality Transfer: A Stereodivergent Entry to Cyanocyclopropanes [PDF]

Angewandte Chemie, Volume 137, Issue 24, June 10, 2025.
The synthesis of cyanocyclopropanes is achieved via asymmetric nitrogen insertion into prochiral cyclobutanones. Key mechanistic steps involve an organocatalyzed asymmetric condensation followed by chirality transfer via an intercepted Neber rearrangement.
Marlene Arnold, Jasmin Hammes, Mike Ong, Christian Mück‐Lichtenfeld, Johannes M. Wahl   +4 more
wiley   +3 more sources

A Study of Palladium Catalyzed Intra/Intermolecular Cascade Cross Coupling/Cyclizations Involving Bicyclopropylidene

Molecules, 2014
The compounds [3-(2-Bromocyclohex-2-enyloxy)prop-1-ynyl]-tert-butyl-dimethylsilane 3, [4-(2-bromocyclohex-2-en-1-yloxy)but-2-yn-1-yloxy]tert-butyldimethylsilane 5 and dimethyl 2-(2-bromocyclohex-2-enyl)-2-(3-(tert-butyldimethylsilanyl)prop-2-ynyl ...
Aydin Demircan
doaj   +1 more source

Synthesis of cyclopropyl-substituted furans by Brønsted acid promoted cascade reactions [PDF]

, 2015
Chloroacetic acid promotes an efficient and diastereoselective intramolecular cascade reaction of electron-deficient ynenones to deliver products featuring a 2,3,5-trisubstituted furan bearing a fused cyclopropyl substituent at the 5-position ...
Achmatowicz, Albrecht, Barluenga, Benary, Boto, Casey, Ciufolini, Clark, Corma, Csuk, Csuk, Donaldson, Donohoe, Fedoryński, Feist, Fritz, Gandini, Gilchrist, González, González, Hashmi, Hou, Högberg, Jung, Knorr, Kobayashi, Krasnaya, Kuroda, Lebel, Li, Li, Lipshutz, Ma, MacMillan, Paal, Pellissier, Ripaud, Sperry, Vicente, Wang, Wessjohann, Wipf, Wu, Xia, Yang, Zhang, Zimmerman   +46 more
core   +2 more sources

Copper, Boron and Vinyl Epoxides: from 1,4-Diols to Cyclopropylboronates

CHIMIA, 2020
Herein we describe the reactivity found between vinyl epoxides and catalytically generated copper-boryl complexes. By tuning the substituents of the alkene and/or the reaction conditions, 1,4-diols, allylic alcohols or cyclopropylboronates can be ...
Luis Novoa, Laura Trulli, Alejando Parra, Mariola Tortosa   +3 more
doaj   +1 more source

Photoredox-catalyzed oxo-amination of aryl cyclopropanes

Nature Communications, 2019
The ring-opening and functionalization of electronically unbiased cyclopropanes is highly challenging to achieve in a regioselective fashion. Here, the authors report a mild photoredox-coupled oxoamination of electronically unactivated aryl cyclopropanes
Liang Ge, Ding-Xing Wang, Renyi Xing, Di Ma, Patrick J. Walsh, Chao Feng   +5 more
doaj   +1 more source

The Solubility Studies and the Complexation Mechanism Investigations of Biologically Active Spiro[cyclopropane-1,3′-oxindoles] with β-Cyclodextrins

Pharmaceutics, 2023
In this work, we first improved the aqueous solubility of biologically active spiro[cyclopropane-1,3′-oxindoles] (SCOs) via their complexation with different β-cyclodextrins (β-CDs) and proposed a possible mechanism of the complex formation.
Anna A. Kravtsova, Anna A. Skuredina, Alexander S. Malyshev, Irina M. Le-Deygen, Elena V. Kudryashova, Ekaterina M. Budynina   +5 more
doaj   +1 more source