Results 41 to 50 of about 19,882 (280)
A valuable upgrade to the portfolio of cycloaddition reactions [PDF]
, 2016 The author thanks EaStCHEM for financial support.Recently Antonchick and Manna described a unique annulation that knits together three acetophenones to construct cyclopropanes. The cascade is mediated by organo-copper and free radical species and amounts
Walton, John C.
core +1 more source
CHIMIA, 1975 The competitive formation of oxiranes 1 and cyclopropanes 2 in the reaction of 2-halogeno-acrylic acid-derivatives, carbonyl-compounds and bases is discussed.
R. Scheffold +4 more
doaj +1 more source
Anesthesia & Analgesia, 1940 Bibliography: p. 155-165. ; Mode of access: Internet.
openaire +2 more sources
New Initiation Modes for Directed Carbonylative C-C Bond Activation:Rhodium-Catalyzed (3+1+2) Cycloadditions of Aminomethylcyclopropanes [PDF]
, 2016 Under carbonylative conditions, neutral Rh(I)-systems modified with weak donor ligands (AsPh3 or 1,4-oxathiane) undergo N-Cbz, N-benzoyl, or N-Ts directed insertion into the proximal C–C bond of aminomethylcyclopropanes to generate rhodacyclo ...
Bower, John +4 more
core +16 more sources
(1RS,3SR)-1-(4-Methylbenzyl)-7-phenyl-5-oxa-6-azaspiro[2.4]hept-6-en-4-one
MolbankThe previously unknown cyclopropane spiro-fused with isoxazol-5-one ((1RS,3SR)-1-(4-methylbenzyl)-7-phenyl-5-oxa-6-azaspiro[2.4]hept-6-en-4-one) was synthesized from benzylideneisoxazol-5-one in 34% yield via double methylene transfer from diazomethane ...
Gleb D. Titov, Nikolai V. Rostovskii
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Access to cyclopropanes with geminal trifluoromethyl and difluoromethylphosphonate groups
Beilstein Journal of Organic Chemistry, 2023 A synthetic route to the bench-stable fluorinated masked carbene reagent diethyl 2-diazo-1,1,3,3,3-pentafluoropropylphosphonate, bearing a trifluoromethyl and a difluoromethyl group is reported for the first time.
Ita Hajdin +5 more
doaj +1 more source
Synthesis and Applications of Rhodacyclopentanones Derived From C-C Bond Activation [PDF]
, 2016 Rhodacyclopentanones, an “sp(3)-rich” class of metallacycle, underpin an emerging range of catalytic methodologies for the direct generation of complex scaffolds.
Bower, John, Shaw, Megan H
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Water‐Catalytic Deconstructive and Proton Transfer Cyclopropanation of Sulfoxonium Ylide with Olefin
Advanced Science, EarlyView.Water‐catalytic deconstructive and proton transfer cyclopropanation of sulfoxonium ylide with olefin is developed through a sequential water‐mediated ring‐closing/opening reaction. This atom‐economical, environmentally friendly methodology offers easy access to a range of cyclopropyl ketones with moderate to good yields.
Xianglin Yu +4 more
wiley +1 more source
Efficient preparation of TMSCCl2Br and its use in dichlorocyclopropanation of electron deficient alkenes [PDF]
, 2016 The reaction of excess TMSCl and LiCCl2Br at low temperature is a technically simple high yield route to TMSCCl2Br. The latter is a stable source of the dichlorobromomethide carbanion, which undergoes 1,4-addition with cyclic nitroalkenes and (E ...
Burroughs, Laurence +3 more
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Advanced Science, EarlyView.L14‐8, a small molecule derived from the marketed drug ezetimibe, potently inhibits advanced prostate cancer independent of androgen receptor signaling. L14‐8 binds PLK1, triggering its ubiquitin‐mediated degradation. This activates TP53‐dependent transcription of SAT1, inducing ferroptosis and suppressing tumor growth in prostate cancer patient ...
Yu Zhang +8 more
wiley +1 more source