Results 131 to 140 of about 10,795 (199)
HeliyonOxidative stress and aberrant inflammatory response have important implications in cyclosporin-induced reproductive functions. Previous studies have shown that agents with antioxidant and anti-inflammatory activities might be beneficial in reversing ...
Obukohwo Mega Oyovwi +8 more
doaj +1 more source
Formulation of diltiazem affects cyclosporin-sparing activity
, 1997 ObjectiveTo consider the effect of changing from a conventional release formulation of diltiazem to the controlled diffusion diltiazem formulation on the cyclosporin-sparing effect in kidney transplant recipients.MethodsSeven stable renal transplant ...
Mathew, T., Morris, R., Jones, T.
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Indomethacin and cyclosporin together produce marked renal vasoconstriction in humans
, 1994 Objective: To test the hypothesis that an imbalance in intrarenal prostaglandins plays a role in cyclosporin-induced nephrotoxicity.Methods and results: Indomethacin was given in combination with cyclosporin to healthy volunteers. Cyclosporin alone (10mg/
Sturrock, Nigel D. C. +2 more
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, 2011 PhDObjectives: Ciclosporin (CsA) is a potent and effective immuno-suppressive drug, but its use is associated with the development of gingival hyperplasia in up to 70% of patients.
Hanino, Mohammad
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The influence of calcium channel blockers on cyclosporin a nephrotoxicity.
, 1990 Intrarenal vasoconstriction is a characteristic feature of cyclosporin A nephrotoxicity. This thesis investigates the effect of nifedipine, a dihydropyridine calcium channel blocker and potent renal vasodilator, on various aspects of experimental and ...
P. G. McNally (7660970)
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Regional differences in vasculotoxic effects of cyclosporin in rate
, 1995 Studies on cyclosporin-induced vasculotoxicity often yielded discrepant results, possibly as a result of differences in study protocols. The aim of the present study was to analyse cyclosporin-induced vasculotoxicity in arteries of different size and ...
De Ridder, Leo +3 more
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The Clinical and Economic Potential of Cyclosporin Drug Interactions
The introduction of cyclosporin significantly improved solid organ transplantation outcomes. However, the costs associated with immunosuppressive therapy increased from approximately $US1000 to $US2000 per patient per year with azathioprine (AZA) and ...
A. Jamal Daoud +3 more
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Southern Medical Journal, 1986
Cyclosporine is a fungal metabolite increasingly used as an immunosuppressive agent in organ transplantation. It provides immunosuppression primarily through reversible inhibition of T-lymphocytes, without myelotoxicity. Cyclosporine appears to inhibit primary activation of helper cells and to decrease the production of lymphokines by these cells ...
S E, Thomas, D S, Gordon
openaire +2 more sources
Cyclosporine is a fungal metabolite increasingly used as an immunosuppressive agent in organ transplantation. It provides immunosuppression primarily through reversible inhibition of T-lymphocytes, without myelotoxicity. Cyclosporine appears to inhibit primary activation of helper cells and to decrease the production of lymphokines by these cells ...
S E, Thomas, D S, Gordon
openaire +2 more sources
Drug Intelligence & Clinical Pharmacy, 1985
Cyclosporine is an immunosuppressant used to prevent the rejection of transplanted kidneys, hearts, and livers. Cyclosporine suppresses T-lymphocyte function without causing myelosuppression, and its pharmacokinetics are highly variable. Compared with conventional immunosuppressive drug therapy, both patient and graft survival improved in patients ...
R J, Ptachcinski +2 more
openaire +2 more sources
Cyclosporine is an immunosuppressant used to prevent the rejection of transplanted kidneys, hearts, and livers. Cyclosporine suppresses T-lymphocyte function without causing myelosuppression, and its pharmacokinetics are highly variable. Compared with conventional immunosuppressive drug therapy, both patient and graft survival improved in patients ...
R J, Ptachcinski +2 more
openaire +2 more sources