Results 81 to 90 of about 95,860 (291)

In vivo effect of the natural antioxidant hydroxytyrosol on cyclosporine nephrotoxicity in rats [PDF]

open access: bronze, 2007
Giovambattista Capasso   +11 more
openalex   +1 more source

The Impact of Methotrexate on Cardiovascular Outcomes in Psoriasis: A Systematic Review and Meta‐Analysis

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Psoriasis is a chronic immune‐mediated inflammatory disease with a global prevalence of 2%–3% and 1.3% in Brazil. It is associated with comorbidities such as obesity, hypertension, and diabetes, all of which contribute to increased cardiovascular risk due to systemic inflammation and endothelial dysfunction.
Tiago A. S. Costa   +2 more
wiley   +1 more source

Unravelling the Major Cardiovascular Risks of Systemic Psoriasis Medications: A Literature Systematic Review

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Psoriasis is a chronic inflammatory dermatological condition associated with an elevated risk of cardiovascular events (CVEs). Systemic therapies have transformed disease management, but their cardiovascular (CV) safety profiles remain incompletely understood and inconsistently reported.
Mai Thi Hoai Son   +10 more
wiley   +1 more source

Cyclosporine therapy during the COVID-19 pandemic [PDF]

open access: bronze, 2020
Lidia Rudnicka   +7 more
openalex   +1 more source

Dupilumab and Systemic Hematologic Malignancies: Case Series and Literature Review

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Atopic dermatitis (AD) is a chronic inflammatory skin disease affecting 15%–20% of children and 3%–10% of adults. An increased risk of systemic lymphomas – but not leukemias – has been reported in patients with AD. Dupilumab, a monoclonal IgG4 antibody targeting IL‐4 and IL‐13 signaling, is approved for moderate‐to‐severe AD and is ...
Nello Tommasino   +3 more
wiley   +1 more source

Minor Contribution of UGT1A1 Inhibition to Atazanavir‐Related Bilirubin Elevation Supported by Conservative PBPK Modeling and Clinical Data

open access: yes
Clinical Pharmacology &Therapeutics, EarlyView.
Jin Dong   +8 more
wiley   +1 more source

Characteristics of Adult Patients With Atopic Dermatitis Initiating Biologics and Janus Kinase Inhibitors in the CorEvitas Atopic Dermatitis Registry

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Biologics and Janus kinase inhibitors (JAKi) are two advanced systemic treatment options for patients with atopic dermatitis (AD). The decision to initiate one of these therapies is complex and may be driven by many factors.
Eric L. Simpson   +12 more
wiley   +1 more source

A comparative analysis of drug-induced kidney injury adverse reactions between cyclosporine and tacrolimus based on the FAERS database

open access: yesBMC Immunology
Background This study utilizes the FDA Adverse Event Reporting System (FAERS) database to compare the adverse reaction signals of cyclosporine and tacrolimus, two widely used immunosuppressants, in relation to drug-induced kidney injury. The findings aim
Min Xu, Shanggang Xu, Xueliang Yi
doaj   +1 more source

The Effect of Social Media Intervention as a Reminder and Educational Tool to Increase Treatment Adherence in Patients With Psoriasis: A Randomized Controlled Trial

open access: yesJEADV Clinical Practice, EarlyView.
In a 12‐week randomized trial of 159 psoriasis patients, educational messages and treatment reminders delivered through Facebook improved treatment adherence, reduced disease severity, and enhanced quality of life. Three times‐weekly messages provided the greatest benefits, including superior adherence, clearer skin, and higher patient satisfaction ...
Jennifer Lavina T. Ngo   +1 more
wiley   +1 more source

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