Results 51 to 60 of about 15,168 (224)
Autophagy in PE: Dispute, Role and Potential Target
Cell Proliferation, EarlyView.Autophagy homeostasis serves as a central hub regulating vascular remodelling during pregnancy. It integrates maternal, genetic, and fetal factors; shapes the functions of immune cells (NK cells, macrophages, and T cells); restrains endothelial inflammatory responses (cytokines, endothelial cell, oxidative/ER stress, and protein aggregation); and ...
Miao Xu +12 more
wiley +1 more source
Clinical relevance of P-glycoprotein expression in haematological malignancies [PDF]
, 1994 Although, generally speaking, haematological malignancies are chemotherapy-responsive tumours and high remission induction rates are obtained, disease-related death is the rule rather than the exception.
Nooter, K. (Kees) +1 more
core +2 more sources
European Journal of Clinical Investigation, EarlyView.Our study demonstrates that total BCAA levels increase following liver transplantation. In patients with cirrhosis, higher total BCAA levels are associated with a reduced risk of all‐cause mortality. However, while this association is not observed in liver transplant recipients, elevated total BCAA levels are strongly linked to an increased risk of new‐
Yakun Li +9 more
wiley +1 more source
Binding of Different Cyclosporin Variants to Micelles Evidenced by NMR and MD Simulations. [PDF]
Membranes (Basel), 2023 Kobchikova PP, Efimov SV, Klochkov VV.
europepmc +1 more source
SMB Operation for Three-Fraction Separations: Purification of Plasmid DNA [PDF]
, 2018 The Simulated Moving Bed technology is extended to incorporate a cleaning in place step, and it is then applied by exploiting size exclusion chromatography to purify plasmid DNA.
Makart, Stefan +4 more
core
Next-generation sequencing approach for connecting secondary metabolites to biosynthetic gene clusters in fungi [PDF]
, 2015 Genomics has revolutionized the research on fungal secondary metabolite (SM) biosynthesis. To elucidate the molecular and enzymatic mechanisms underlying the biosynthesis of a specific SM compound, the important first step is often to find the genes that
Cacho, Ralph A. +2 more
core +1 more source
Solid organ transplantation in people with HIV: Outcomes, obstacles and opportunities
HIV Medicine, EarlyView.Abstract Objective People with HIV experience disparate access to solid organ transplantation (SOT), despite mounting evidence for comparable outcomes. This review aims to understand the outcomes following SOT, obstacles to SOT and opportunities to improve access and outcomes following SOT.
David W. J. Griffin +3 more
wiley +1 more source
Cyclosporine A in Ullrich Congenital Muscular Dystrophy: Long-Term Results [PDF]
, 2011 Six individuals with Ullrich congenital muscular dystrophy (UCMD) and mutations in the genes-encoding collagen VI, aging 5–9, received 3–5 mg/kg of cyclosporine A (CsA) daily for 1 to 3.2 years.
Angelin, Alessia +13 more
core +3 more sources
Pediatric Dermatology, EarlyView.ABSTRACT Pityriasis rubra pilaris (PRP) is a rare, chronic papulosquamous disorder with limited treatment options in pediatric patients. We report the case of a 9‐year‐old boy with juvenile PRP (type III), who achieved complete disease remission after treatment with secukinumab, an IL‐17A inhibitor, following initial therapeutic resistance to topical ...
Zeno Fratton +2 more
wiley +1 more source