Results 81 to 90 of about 1,823 (213)
From January 2024 to May 2025, 207 patients (68.6% females) affected by CHE were enrolled to be clinically and etiologically investigated using a case report form specifically developed. The accurate workup led to clinical and etiological classification of CHE in about 80% of patients, allowing tailored treatment strategies. ABSTRACT Background Chronic
Rosella Gallo +21 more
wiley +1 more source
What Is Your Diagnosis? Cutaneous Mass in a Dog
Veterinary Clinical Pathology, EarlyView.
Ester Quilez, Shannon L. Donahoe
wiley +1 more source
A comprehensive stereochemical and physicochemical survey of cyclic heptapeptide chemical space reveals that the mortiamide natural product scaffold possesses intrinsically low aqueous solubility and forms amyloid‐like fibril aggregates. Multiple orthogonal assays demonstrate that the observed cytotoxicity arises from colloidal aggregation rather than ...
Jaru Taechalertpaisarn +8 more
wiley +1 more source
GATA2 Mutations Predict Poor Prognosis in Transplanted Myeloid Neoplasms
ABSTRACT Background GATA binding protein 2 (GATA2) plays a crucial role in the differentiation, proliferation, and maintenance of hematopoietic stem cells (HSCs). GATA2 mutations have been identified in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS), but the impact of somatic GATA2 mutations on prognosis remains controversial ...
Xian Zhang +8 more
wiley +1 more source
Catheter ablation for complex atrial arrhythmias in solid organ transplant recipients is feasible using contemporary techniques, with arrhythmia‐free survival and periprocedural complication rates comparable to matched non‐transplant controls. ABSTRACT Introduction Atrial arrhythmias are common among solid organ transplant recipients and independently ...
Piotr Gardziejczyk +6 more
wiley +1 more source
Effect of the modulation of the membrane lipid composition on the localization and function of P-glycoprotein in MDR1-MDCK cells [PDF]
Summary: Multidrug resistance (MDR) is a major obstacle in cancer therapy. It results from different mechanisms; among them is P-glycoprotein (P-gp)-mediated drug efflux out of cells. The mechanism of action remains elusive.
Günthert, Maja +3 more
core
Tolypocladamide H and the Proposed Tolypocladamide NRPS in Tolypocladium Species. [PDF]
Tehan RM +10 more
europepmc +1 more source
Abstract The endoplasmic reticulum (ER) provides a specialized environment for the folding of secreted and membrane proteins, a process supported by many different chaperones. Among these chaperones, peptidyl‐prolyl cis/trans isomerases (PPIases) catalyze a rate‐limiting conformational step in protein folding, yet the principles governing isoform ...
Sarah C. DeVoe +7 more
wiley +1 more source
Congenital aniridia: European COST action ANIRIDIA‐NET guidelines for diagnosis, management and care
Abstract Congenital aniridia is a rare ocular disorder affecting the majority of eye structures and can be associated with systemic manifestations. The main visible phenotypic characteristic is the partial or complete absence of the iris; however, foveal hypoplasia is a more frequent and reliable clinical sign. Other ocular comorbidities are associated
Davide Romano +26 more
wiley +1 more source
Use of Cyclosporine Therapy in Dermatology During COVID-19 Pandemic. [PDF]
Pathania YS.
europepmc +1 more source

