Results 81 to 90 of about 1,823 (213)

Real‐Life Workup of Chronic Hand Eczema Using a Dedicated Case Report Form: A SIDAPA Multicentre Study

open access: yesContact Dermatitis, Volume 94, Issue 6, Page 662-676, June 2026.
From January 2024 to May 2025, 207 patients (68.6% females) affected by CHE were enrolled to be clinically and etiologically investigated using a case report form specifically developed. The accurate workup led to clinical and etiological classification of CHE in about 80% of patients, allowing tailored treatment strategies. ABSTRACT Background Chronic
Rosella Gallo   +21 more
wiley   +1 more source

What Is Your Diagnosis? Cutaneous Mass in a Dog

open access: yes
Veterinary Clinical Pathology, EarlyView.
Ester Quilez, Shannon L. Donahoe
wiley   +1 more source

Exploring Passive Permeability Profiles of Cyclic Heptapeptide Chemical Space Uncovers Bioactivity of Mortiamide Scaffold Driven by Colloidal Aggregation

open access: yesChemBioChem, Volume 27, Issue 9, 14 May 2026.
A comprehensive stereochemical and physicochemical survey of cyclic heptapeptide chemical space reveals that the mortiamide natural product scaffold possesses intrinsically low aqueous solubility and forms amyloid‐like fibril aggregates. Multiple orthogonal assays demonstrate that the observed cytotoxicity arises from colloidal aggregation rather than ...
Jaru Taechalertpaisarn   +8 more
wiley   +1 more source

GATA2 Mutations Predict Poor Prognosis in Transplanted Myeloid Neoplasms

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background GATA binding protein 2 (GATA2) plays a crucial role in the differentiation, proliferation, and maintenance of hematopoietic stem cells (HSCs). GATA2 mutations have been identified in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS), but the impact of somatic GATA2 mutations on prognosis remains controversial ...
Xian Zhang   +8 more
wiley   +1 more source

Efficacy and Safety of Catheter Ablation for Atrial Arrhythmias in Solid Organ Transplant Recipients: A Single‐Center Experience

open access: yesClinical Cardiology, Volume 49, Issue 5, May 2026.
Catheter ablation for complex atrial arrhythmias in solid organ transplant recipients is feasible using contemporary techniques, with arrhythmia‐free survival and periprocedural complication rates comparable to matched non‐transplant controls. ABSTRACT Introduction Atrial arrhythmias are common among solid organ transplant recipients and independently ...
Piotr Gardziejczyk   +6 more
wiley   +1 more source

Effect of the modulation of the membrane lipid composition on the localization and function of P-glycoprotein in MDR1-MDCK cells [PDF]

open access: yes, 2018
Summary: Multidrug resistance (MDR) is a major obstacle in cancer therapy. It results from different mechanisms; among them is P-glycoprotein (P-gp)-mediated drug efflux out of cells. The mechanism of action remains elusive.
Günthert, Maja   +3 more
core  

Tolypocladamide H and the Proposed Tolypocladamide NRPS in Tolypocladium Species. [PDF]

open access: yesJ Nat Prod, 2022
Tehan RM   +10 more
europepmc   +1 more source

Biophysical characterization of Cyclophilin B reveals membrane localization as its primary functional determinant as a prolyl isomerase

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract The endoplasmic reticulum (ER) provides a specialized environment for the folding of secreted and membrane proteins, a process supported by many different chaperones. Among these chaperones, peptidyl‐prolyl cis/trans isomerases (PPIases) catalyze a rate‐limiting conformational step in protein folding, yet the principles governing isoform ...
Sarah C. DeVoe   +7 more
wiley   +1 more source

Congenital aniridia: European COST action ANIRIDIA‐NET guidelines for diagnosis, management and care

open access: yesActa Ophthalmologica, Volume 104, Issue 3, Page 267-279, May 2026.
Abstract Congenital aniridia is a rare ocular disorder affecting the majority of eye structures and can be associated with systemic manifestations. The main visible phenotypic characteristic is the partial or complete absence of the iris; however, foveal hypoplasia is a more frequent and reliable clinical sign. Other ocular comorbidities are associated
Davide Romano   +26 more
wiley   +1 more source

Home - About - Disclaimer - Privacy