Results 101 to 110 of about 3,601 (247)

Cylindrospermopsin enhances the conjugative transfer of plasmid-mediated multi-antibiotic resistance genes through glutathione biosynthesis inhibition.

Ecotoxicology and Environmental Safety
Cylindrospermopsin (CYN), a cyanobacterial toxin, has been detected in the global water environment. However, information concerning the potential environmental risk of CYN is limited, since the majority of previous studies have mainly focused on the ...
Shu-Ran Yang, Jinrui Cao, Chen Zhao, Xi Zhang, Chen-Yu Li, Shang Wang, Xiaobo Yang, Z. Qiu, Chao Li, Jing-Feng Wang, Bin Xue, Zhiqiang Shen   +11 more
semanticscholar   +1 more source

Characterization of the Gene Cluster Responsible for Cylindrospermopsin Biosynthesis [PDF]

Applied and Environmental Microbiology, 2008
ABSTRACTToxic cyanobacterial blooms cause economic losses and pose significant public health threats on a global scale. Characterization of the gene cluster for the biosynthesis of the cyanobacterial toxin cylindrospermopsin (cyr) inCylindrospermopsis raciborskiiAWT205 is described, and the complete biosynthetic pathway is proposed.
Troco Kaan, Mihali, Ralf, Kellmann, Julia, Muenchhoff, Kevin D, Barrow, Brett A, Neilan   +4 more
openaire   +2 more sources

Synthetic analogues of cyanobacterial alkaloid cylindrospermopsin and their toxicological activity [PDF]

, 2017
Highlights•The role of the C7-OH group in the activity of cylindrospermopsin 1 is unknown.•Synthetic analogues (11a–c) of cylindrospermopsin 1 were prepared.•Toxicity of these analogues was compared with 1 using human neutrophils in vitro.•The greatest ...
Daniel M. Evans, Piotr Rzymski, Caspari, Thomas, Elwood, Jessica ML, Patrick J. Murphy, Poniedziałekc, Barbara, Jessica M.L. Elwood, Barbara Poniedziałek, Cartmell, Christopher, Thomas Caspari, Murphy, Patrick, Fituri, Hisham, Rzymskic, Piotr, Christopher Cartmell, Evans, Daniel, Hisham S. Fituri   +15 more
core   +1 more source

Microcystin-LR and Cylindrospermopsin Induced Alterations in Chromatin Organization of Plant Cells

Marine Drugs, 2013
Cyanobacteria produce metabolites with diverse bioactivities, structures and pharmacological properties. The effects of microcystins (MCYs), a family of peptide type protein-phosphatase inhibitors and cylindrospermopsin (CYN), an alkaloid type of protein
Gábor Vasas, Márta M-Hamvas, Csaba Máthé   +2 more
doaj   +1 more source

Saturated constructed wetlands for the remediation of cylindrospermopsin and microcystin-LR: Plants, microbes, and biodegradation pathways.

Science of the Total Environment
Harmful cyanobacterial blooms will be more intense and frequent in the future, contaminating surface waters with cyanotoxins and posing a threat to communities heavily reliant on surface water usage for crop irrigation.
A. M. Quer, C. Arias, Lea Ellegaard-Jensen, A. Johansen, Maria Lund Paulsen, Ada Pastor, P. N. Carvalho   +6 more
semanticscholar   +1 more source

Cyanobacteria and Cyanotoxins in Mediterranean Reservoirs: Ecological Variability, Risks and Implications for Water Quality Assessment

Ecohydrology, Volume 19, Issue 1, January‐February 2026.
ABSTRACT The increasing demand for freshwater, in combination with climate change and pollution, compromises the quality and quantity of water resources. These pressures have intensified cyanobacterial blooms, including toxic events that threaten human health and aquatic ecosystems. This study complements the objectives of the Water Framework Directive
Ivo Pinto, Raquel Silva, Guilherme Scotta Hentschke, Vítor Vasconcelos, João Morais, Luísa Azevedo, Sara C. Antunes   +6 more
wiley   +1 more source

Time-dependence of lung injury in mice acutely exposed to cylindrospermopsin [PDF]

, 2012
Cylindrospermopsin is a cyanobacterial toxin of increasing environmental importance, as it can lead to disease if orally or intravenously absorbed. However, its in vivo lung impairment has not been documented.
Zin, Walter Araujo, Azevedo, S.M.F.O., Valença, S.S., Faffe, D.S., Oliveira, V.R., Soares, R.M., Ferreira, T.S., Carvalho, G.M.C., Avila, M.B.   +8 more
core   +1 more source

The languages spoken in the water body (or the biological role of cyanobacterial toxins)

Frontiers in Microbiology, 2012
Although intensification of toxic cyanobacterial blooms over the last decade is a matter of growing concern due to bloom impact on water quality, the biological role of most of the toxins produced is not known.
Aaron eKaplan, Moshe eHarel, Ruth N Kaplan-Levy, Ora eHadas, Assaf eSukenik, Elke eDittmann   +5 more
doaj   +1 more source

Genotoxic Effects of Cylindrospermopsin, Microcystin-LR and Their Binary Mixture in Human Hepatocellular Carcinoma (HepG2) Cell Line

Toxins, 2020
Simultaneous occurrence of cylindrospermopsin (CYN) and microcystin-LR (MCLR) has been reported in the aquatic environment and thus human exposure to such mixtures is possible.
Leticia Díez-Quijada, Klara Hercog, Martina Štampar, Metka Filipič, Ana M. Cameán, Ángeles Jos, Bojana Žegura   +6 more
doaj   +1 more source

Nephrotoxicity of Cylindrospermopsin (CYN) and Microcystin-LR (MC-LR) on Mammalian Kidney: Wistar Rat as a Model Assessment

Nature Environment and Pollution Technology
Naturally derived cyanotoxins, cylindrospermopsin (CYN), and microcystin-LR (MC-LR) have shown hepatotoxic and nephrotoxic effects in several studies. The present study aimed to determine the possible nephrotoxicity of MC-LR and CYN on mammalian kidneys ...
H. A. S. N. Abeysiri, J. K. P. Wanigasuriya, T. Suresh, D. H. Beneragama, P. Manage   +4 more
semanticscholar   +1 more source