Results 101 to 110 of about 2,702,703 (186)
Background and aims: CYP17A1 and CYP19A2 enzymes are key proteins in constructing and regulating steroid hormones such as cortisol, testosterone and estrogen. But the effect of exercise on these two proteins in ovary tissue has not been investigated yet.
maryamosadat miri +4 more
doaj
Most anurans have no identified sex-markers; therefore, alternative methods for identification of early changes in sex ratios are required. In this study, Lithobates sylvaticus and Silurana tropicalis tadpoles were sampled at different developmental ...
Lanctôt C. (4135957) +6 more
core +1 more source
The nucleosome occupancy in the CYP19 locus.
(A-C) ChIP assays with anti-pan-histone H3 revealed the amount of nucleosomes in the CYP19 locus in HepG2 (A), KGN (B), or HeLa cells (C). The nucleosome level is expressed as a percentage of total input chromatin (IP/Input).
Naoe Kotomura (746485) +2 more
core +1 more source
Variable Cre Recombination Efficiency in Placentas of Cyp19-Cre ROSA mT/mG Transgenic Mice
The aromatase-Cre recombinase (Cyp19-Cre) transgenic mouse model has been extensively used for placenta-specific gene inactivation. In a pilot study, we observed unexpected phenotypes using this mouse strain, which prompted an extensive characterization ...
Nayak, Neha +7 more
core
PubMedID: 21948762Many clinical conditions, including osteoporosis, are associated with serum levels of sex steroids. Enzymes that regulate rate-limiting steps of steroidogenic pathways, such as CYP17 and CYP19, are also regarded as significant factors ...
Kocaturk-Sel S. +16 more
core +1 more source
Background: Aromatase is a key enzyme in the synthesis of estrogen. This enzyme is encoded by the cytochrome P-450 (CYP19) gene. Overexposure of cells to estrogen causes breast carcinoma and breast cancer patients show a higher level of aromatase ...
Seyed Morteza Javadirad +2 more
doaj
Neonicotinoids induce a promoter-switch in CYP19 expression in breast-cancer cells and alter aromatase activity and hormone production in a feto-placental co-culture model [PDF]
In estrogen-dependent breast cancer, CYP19 expression is increased via activation of several promoters (PII, I.3, I.7) and by the inhibition of normal I.4 promoter.
Denison, Michael S. +2 more
core +1 more source
The purpose of this study was to identify mutations in melatonin receptor 1A (MTNR1A) and aromatase cytochrome P450 (CYP19) genes using PCR-RFLP technique and their associations with sperm quality and testicular size traits in Sanjabi breed rams.
Zahra Nikousefat +4 more
core +1 more source
Detection of CYP17 and CYP19 Gene Polymorphisms in Endometriosis
Gurgan, T +5 more
openaire +2 more sources
Many natural and synthetic compounds present in the environment exert a number of adverse effects on the exposed organisms, leading to endocrine disruption, for which they were termed endocrine disrupting chemicals (EDCs).
Segner, Helmut +14 more
core +1 more source

