Results 191 to 200 of about 45,621 (284)

CYP2C19*2 Allele [PDF]

, 2020
openaire   +1 more source

Health Benefits and Therapeutic Potential of Quercetin

Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Quercetin, a polyphenolic compound prevalent in many fruits, vegetables, and other dietary sources, has attracted considerable interest due to its extensive health benefits. This review examines its diverse biological properties, particularly its antioxidant and anti‐inflammatory effects. The study integrates recent scientific findings to elucidate the
Mahendra Aryal, Kim Wei Chan
wiley   +1 more source

CYP2C19*5 Allele [PDF]

, 2020
openaire   +1 more source

Enhanced CYP2C19-mediated drug-drug interaction risk with escitalopram in geriatric populations. [PDF]

Front Pharmacol
Byoun S, Heo DG, Lee M, Lee R, Li Y, Lee JY, Hong E, Lee W.   +7 more
europepmc   +1 more source

Ergostanes and Cytochalasin From the Fruiting Bodies of Xylaria longipes Nitschke and Their Cytotoxicity Evaluation

Journal of Chemistry, Volume 2026, Issue 1, 2026.
Four ergostanes—ergosta‐7,22,24(28)‐trien‐3β‐ol (1), ergosta‐7,24(28)‐dien‐3‐one (2), ergosta‐7,22,24(28)‐trien‐3‐one (3), and ergosta‐4,6,8(14),22‐tetraen‐3‐one (4)—and one cytochalasin, zygosporin D (5), were isolated from Xylaria longipes. Two compounds, 2 and 3, are novel but have a similar structure to Compound (1), except for the keto group at ...
Alice W. Njue, Josiah Omolo, Moses K. Langat, Dulcie A. Mulholland, Njogu M. Kimani, Sohini Basu Roy   +5 more
wiley   +1 more source

Licochalcone A as Novel Multitarget Inhibitors via AChE, BuChE, and Synapsin III for Therapeutic Intervention Against Alzheimer’s Disease: Computer‐Aided Drug Design

Journal of Chemistry, Volume 2026, Issue 1, 2026.
Alzheimer’s disease (AD) is characterized by key pathological features, including cholinergic dysfunction, amyloid‐beta (Aβ) aggregation, and disrupted synaptic transmission, positioning proteins such as acetylcholinesterase (AChE), butyrylcholinesterase (BuChE), and Synapsin III as critical targets for therapeutic strategies.
Ali Alimari, Bagher Seyedalipour, Payam Baziyar, Ehsan Joz Jalalian, Sohini Basu Roy   +4 more
wiley   +1 more source

CYP2C19*4 Allele [PDF]

, 2020
openaire   +1 more source

Genetische Determinanten der Clopidogrel-Response - Untersuchungen zu CYP2C19*2 und CYP2C19*17 [PDF]

, 2017
Nach einer Koronarintervention erhalten Patienten eine duale antithrombozytäre Therapie mit ASS und Clopidogrel um das peri- und postinterventionelle Risiko thrombotischer Komplikationen zu reduzieren. Für Clopidogrel ist das individuelle Ansprechen auf die Behandlung jedoch nicht einheitlich.
openaire  

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP2C19 and Voriconazole Therapy

Clinical pharmacology and therapy, 2017
Brad Moriyama, A. Obeng, A. Obeng, Julia M. Barbarino, S. Penzak, Stacey A. Henning, Stuart A. Scott, José A G Agúndez, J. Wingard, Howard L. McLeod, Teri E. Klein, S. J. Cross, K. Caudle, Thomas J. Walsh   +13 more
semanticscholar   +1 more source

Antihemolytic and Thrombolytic Potential of Ocimum basilicum Seed Extract, Bioactive Compounds, and Docking With VanA Ligase in Vancomycin‐Resistant Staphylococci

Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.
Ocimum basilicum is an important alternative source to explore diverse anti‐infective compounds. In the present study, aqueous seed extract of O. basilicum was used to identify bioactive compounds with antihemolytic, thrombolytic, antivancomycin‐resistant Staphylococcus aureus and antivancomycin‐resistant S. epidermidis activity.
Khalaf F. Alsharif, Hazir Rahman, Zhengwei Huang   +2 more
wiley   +1 more source