Results 211 to 220 of about 27,792 (251)

Association between CYP2D6 genotype and treatment effectiveness and safety in 99 hospitalized patients with major depressive disorder a retrospective cohort study CYP2D6 genotype and antidepressant response. [PDF]

Pharmacogenomics J
Petković Ćurčin A, Jeremić A, Joković D, Šupić G, Simić K, Milosavljević F, Stojanović Z, Jukić MM.   +7 more
europepmc   +1 more source

Genotype-predicted drug response phenotypes and their co-occurrence with dispensed medicines among 738,531 participants in the UK Our Future Health study

Rentsch CT, Bhaskaran K, Pavicic M, Warren HR, Matthewman J, Barry E, Rafi I, Hayward J, Gerada C, Shah A, Munroe PB, Silver MJ, Pirmohamed M.   +12 more
europepmc   +1 more source

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CYP2C19 gene polymorphism in Ningxia

Pharmacological Reports, 2023
Poor metabolizer (PM) status of CYP2C19 can be a predisposing factor for developing gastric cancer in H. pylori-infected patients. It is unclear whether PM status of CYP2C19 can also be a potential factor for H.pylori infection in healthy people.We used high-throughput sequencing to detect single nucleotide polymorphisms (SNPs) at just three loci ...
Feihu Bai, Ximei Li
exaly   +3 more sources

Genetic polymorphism of CYP2C19 in a Jordanian population: influence of allele frequencies of CYP2C19*1 and CYP2C19*2 on the pharmacokinetic profile of lansoprazole

Molecular Biology Reports, 2011
To relate the pharmacokinetics of orally administered lansoprazole in healthy adult Jordanian men with CYP2C19 polymorphisms and to determine the percentage of CYP2C19 polymorphism in Jordanian population and the allelic frequency of CYP2C19*2 and CYP2C19*3.
Nancy Hakooz, Tawfiq Arafat
exaly   +3 more sources

Clopidogrel Inhibits CYP2C19‐Dependent Hydroxylation of Omeprazole Related to CYP2C19 Genetic Polymorphisms

Journal of Clinical Pharmacology, 2009
This study explores the impact of clopidogrel on the pharmacokinetics of omeprazole related to CYP2C19 genetic polymorphisms. Twelve healthy volunteers (6 CYP2C19*1/*1, 5 CYP2C19*2/*2, and 1 CYP2C19*2/*3) are enrolled in a 2‐phase randomized crossover trial.
H H Zhou
exaly   +3 more sources