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[Genotyping of CYP2D6 and CYP2C19].
Casopis lekaru ceskych, 2008Polymorphisms in drug metabolizing enzymes are considered as a major factor influencing the incidence of adverse drug reactions or failure of pharmacotherapy. Our aim was to compare the distribution of functional polymorphisms in the genes CYP2D6 and CYP2C19 between healthy control group and of patients reffered to our department due to adverse drug ...
O, Slanar +6 more
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The Metabolism of Clopidogrel: CYP2C19 Is a Minor Pathway
The Journal of Clinical Pharmacology, 2016AbstractThe major metabolic pathway of clopidogrel is conversion to carboxylic acid by an esterase (CES1), forming clopidogrelic acid (SR26334) that is inactive. There is agreement on the structure of the active metabolite; however, there are differing views about the mechanism of its formation.
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CYP2C19*2 and CYP2C19*3 allelomorphism in Turkish population
International Journal of Cardiology, 2017openaire +3 more sources
Limited frequency of the CYP2C19*17 allele and its minor role in a Japanese population
British Journal of Clinical Pharmacology, 2008Hiroshi Yamazaki
exaly
The CYP2C19*17 variant is not independently associated with clopidogrel response
Journal of Thrombosis and Haemostasis, 2013Alan Shuldiner, Braxton Mitchell
exaly
Genetic polymorphisms of CYP2C9 and CYP2C19 in the Beninese and Belgian populations
British Journal of Clinical Pharmacology, 2003Jean-Luc Gala
exaly