Results 151 to 157 of about 8,876 (157)
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Genetic variance in CYP2C8 and increased risk of myocardial infarction
Pharmacogenetics and Genomics, 2010Epoxyeicosatrienoic acids (EETs) are important mediators in vasodilatation, acting as endothelium-derived hyperpolarizing factors. CYP2C enzymes catalyze the metabolism of arachidonic acid to EETs. Genetic variation within the genes encoding for these enzymes may result in differences in vascular response, among others in myocardial tissue, and may ...
Rodenburg, Eline +7 more
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Frequency of CYP2C8*2 and CYP2C8*3 alleles in Ugandan children exposed to Malaria
2014aaa
G. M. Paganotti +6 more
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The impact of a CYP2C8-CYP3A4 protein–protein interaction on time dependent inhibition of CYP2C8
Drug Metabolism and Pharmacokinetics, 2018Andrea Whitcher-Johnstone, Tom S. Chan
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CYP2C8 polymorphisms among malaria patients in Guinea-Bissau
2008Cytochrome P450 (CYP) 2C8 is the major enzyme responsible for the metabolism of many clinically important drugs including the antimalarial amodiaquine (AQ). This study investigated in 91 malaria-infected patients from Guinea-Bissau, the prevalence of CYP2C8 variants CYP2C8*2, CYP2C8*3 and CYP2C8*4, which may have important clinical implications for the
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Selexipag contraindicated with strong CYP2C8 inhibitors
Reactions Weekly, 2017openaire +1 more source