Results 101 to 110 of about 19,211 (198)

Effect of Cytochrome P450 2C9 genetic polymorphism on agomelatine metabolism <i>in vitro</i>. [PDF]

PeerJ
Fang P, Ni J, Shen T, Chen Q, Ye X, Jin J, Dai D, Hu G, Qian J, Cai J, Chen L.   +10 more
europepmc   +1 more source

Induction of cytochrome P450 2C9 and P-glycoprotein activity by antiseizure medications: A systematic review and network meta-analysis. [PDF]

Epileptic Disord
Cohen H, Bahash N, Ben-Shushan T, Matok I, Eyal S.   +4 more
europepmc   +1 more source

Generative Artificial Intelligence-Empowered Virtual Evolution of Enzyme with the VERnet Model. [PDF]

ACS Catal
Li C, Xu W, Yang H, Li Y, Zhang L, Chen Z, Wang S, Xie Y, Li H, Liu Y, Li Y, Lu Z, Zhang C, Yu X, Dai D, Jin P, Xiao F.   +16 more
europepmc   +1 more source

Evaluation of the cytochrome P450-mediated drug interaction profile of olorofim. [PDF]

Antimicrob Agents Chemother
Cornelissen K, Rex JH, Zinzi D, Law D, Upcott Gill R, Jones HM, Maertens J, Chen SC-A, Brüggemann R.   +8 more
europepmc   +1 more source

Sesamin exhibits potential food-drug interactions through the inhibition of cytochrome P450s and human UDP-glucuronosyltransferases <i>in vitro</i>. [PDF]

RSC Adv
Yin H, Zhu L, Wang X, Wang Z, Wang H, Liu Y.   +5 more
europepmc   +1 more source

Explainable Artificial Intelligence Unravels the Possible Distinct Roles of VKORC1 and CYP2C9 in Predicting Warfarin Anticoagulation Control. [PDF]

Med Sci (Basel)
Sridharan K, Sivaramakrishnan G.
europepmc   +1 more source

In Vitro Cytochrome P450 Interaction Profile and ADME Characterisation of Gold(I)-Triphenylphosphine Complexes with 6-Alkoxy-9-deazapurine Ligands. [PDF]

Pharmaceutics
Medvedíková M, Vančo J, Trávníček Z, Anzenbacher P.   +3 more
europepmc   +1 more source

Reconstructing the pharmacogenomic landscape of psychiatric medication metabolism in the Indian population. [PDF]

Commun Med (Lond)
Garg R, Saxena SK, Singh V, Kumar A, Bashir S, Singh H, Chahal N, Sharma I, Sharma V.   +8 more
europepmc   +1 more source

Kinic index: an artificial intelligence-driven predictive model and multitarget drug discovery framework for hepatocellular carcinoma patients. [PDF]

NPJ Precis Oncol
Zhou J, Jiang Y, Yu M, Wang M, Li Y, Ji D, Zhan J, Zhang H.   +7 more
europepmc   +1 more source

In Silico Comparison of Rifampicin and 25-desacetyl Rifampicin-Induced PXR-Mediated CYP450 Transcriptional Response in 3D Primary Human Hepatocytes. [PDF]

Bull Math Biol
Kahiya ET, Smutný T, Smutná L, Duintjer Tebbens J, Pávek P, Bernhauerová V.   +5 more
europepmc   +1 more source