Predicting steady‐state endoxifen plasma concentrations in breast cancer patients by CYP2D6 genotyping or phenotyping. Which approach is more reliable? [PDF]
Milena Gusella +18 more
openalex +1 more source
Genotyping of CYP2D6 Polymorphisms by MALDI-TOF Mass Spectrometry in Sardinian People [PDF]
Matteo Falzoi +3 more
openalex +1 more source
The roles of CYP2D6 and stereoselectivity in the clinical pharmacokinetics of chlorpheniramine [PDF]
Sally Usdin Yasuda +5 more
openalex +1 more source
Polymorphic drug metabolising enzymes:Assessment of activities by phenotyping and genotyping in clinical pharmacology [PDF]
Drug effects (pharmacodynamics) are determined by drug concentration at target site and the affinity of the drug for a target. Pharmacogenetics describes inherited differences in drug metabolising enzyme activities and differences in drug transporters ...
Tamminga, Willem Jan
core +2 more sources
Highly Variable Pharmacokinetics of Tyramine in Humans and Polymorphisms in OCT1, CYP2D6, and MAO-A
Muhammad Rafehi +11 more
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В настоящем номере представлен ряд актуальных обзоров, посвящённых изучению новых лекарственных средств и межлекарственному взаимодействию. Прежде всего, продолжается серия обзоров, связанных с исследованием функционирования и полиморфизма известных ...
doaj
Peculiarities of functioning and polymorphism of cytochrome P450 isoenzyme CYP2D6. Existing methods for determining its activity using endogenous markers.
A. D. Abdrashitov +3 more
doaj
Estimating the Potential Impact of CYP2C19 and CYP2D6 Genetic Testing on Protocol-Based Care for Depression in Canada and the United States [PDF]
Mikayla Fan, Chad Bousman
openalex +1 more source
The association of CYP2D6 gene polymorphisms in the full-length coding region with higher recurrence rate of vivax malaria in Yunnan Province, China [PDF]
Herong Huang +7 more
openalex +1 more source
CYP2D6 genetic polymorphisms are associated with susceptibility to pituitary tumors [PDF]
Several polymorphisms of drug-metabolizing enzymes have been implicated in the susceptibility to tumor development. The role of the CYP2D6, GSTM1 and GSTT1 genes has been extensively studied, with alleles conferring different metabolic efficiencies and ...
Carvalheiro, M +5 more
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