Results 101 to 110 of about 48,854 (243)

Predicting steady‐state endoxifen plasma concentrations in breast cancer patients by CYP2D6 genotyping or phenotyping. Which approach is more reliable? [PDF]

open access: gold, 2020
Milena Gusella   +18 more
openalex   +1 more source

The roles of CYP2D6 and stereoselectivity in the clinical pharmacokinetics of chlorpheniramine [PDF]

open access: bronze, 2002
Sally Usdin Yasuda   +5 more
openalex   +1 more source

Polymorphic drug metabolising enzymes:Assessment of activities by phenotyping and genotyping in clinical pharmacology [PDF]

open access: yes, 2001
Drug effects (pharmacodynamics) are determined by drug concentration at target site and the affinity of the drug for a target. Pharmacogenetics describes inherited differences in drug metabolising enzyme activities and differences in drug transporters ...
Tamminga, Willem Jan
core   +2 more sources

Highly Variable Pharmacokinetics of Tyramine in Humans and Polymorphisms in OCT1, CYP2D6, and MAO-A

open access: gold, 2019
Muhammad Rafehi   +11 more
openalex   +1 more source

FROM THE EDITOR

open access: yesФармакокинетика и Фармакодинамика, 2014
В настоящем номере представлен ряд актуальных обзоров, посвящённых изучению новых лекарственных средств и межлекарственному взаимодействию. Прежде всего, продолжается серия обзоров, связанных с исследованием функционирования и полиморфизма известных ...

doaj  

Review of existing methodologies to assess the activity of CYP2D6 using exogenous and endogenous markers

open access: yesФармакокинетика и Фармакодинамика, 2014
Peculiarities of functioning and polymorphism of cytochrome P450 isoenzyme CYP2D6. Existing methods for determining its activity using endogenous markers.
A. D. Abdrashitov   +3 more
doaj  

CYP2D6 genetic polymorphisms are associated with susceptibility to pituitary tumors [PDF]

open access: yes, 2005
Several polymorphisms of drug-metabolizing enzymes have been implicated in the susceptibility to tumor development. The role of the CYP2D6, GSTM1 and GSTT1 genes has been extensively studied, with alleles conferring different metabolic efficiencies and ...
Carvalheiro, M   +5 more
core  

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