Results 161 to 170 of about 75,915 (258)

CYP3A4*18 Allele [PDF]

, 2020
openaire   +1 more source

The Evolving Role of Ivabradine for Focal Atrial Tachycardia: A Systematic Review

Journal of Arrhythmia, Volume 42, Issue 2, April 2026.
Overview of the evolving role of ivabradine in focal atrial tachycardia (FAT), highlighting its HCN‐mediated mechanism, features of ivabradine‐sensitive FAT, hypothesized predictors of response, special populations requiring special considerations, and potential adverse effects.
Haikal Balweel, Rifqi Rizkani Eri, Sania Zahrani, Kiara Hanna Quinncilla, Novaro Adeneur Tafriend, Agus Harsoyo   +5 more
wiley   +1 more source

Antimicrobial Effect of Spices and Their Phytochemicals: A Novel Approach to Overcoming Antibiotic Resistance

MedComm, Volume 7, Issue 4, April 2026.
This graphical abstract shows the antibacterial potential of phytochemicals from 15 spices, showcasing key compounds, their extraction methods, and mechanisms of action. It highlights membrane disruption, ROS generation, enzyme inhibition, and biofilm prevention as core antibacterial pathways.
Hettiyahandi Binodh De Silva, Yanqi Dai, Shervanthi Homer‐Vanniasinkam, Mohan Edirisinghe   +3 more
wiley   +1 more source

MolViewStories: Interactive molecular storytelling

Protein Science, Volume 35, Issue 4, April 2026.
Abstract Effectively communicating knowledge related to molecular structures and their associated data remains a challenge, as traditional static figures limit interactivity and professional visualization tools often require substantial expertise. MolViewStories addresses these limitations by providing an open‐source, web‐based platform for creating ...
Terézia Slanináková, Zachary Charlop‐Powers, Viktoriia Doshchenko, Alexander S. Rose, Adam Midlik, Anna Sekuła, Neli Fonseca, Kyle L. Morris, Stephen K. Burley, Sameer Velankar, Jennifer Fleming, Brinda Vallat, Ludovic Autin, David Sehnal   +13 more
wiley   +1 more source

Acute Eruption in a Child With Acute Lymphoblastic Leukemia

Pediatric Dermatology, EarlyView.
L. Parra‐Navarro, N. Planella‐Fontanillas, C. Prat   +2 more
wiley   +1 more source

A Clinically Relevant Drug Interaction Between Busulfan and Rifampin in the Setting of Hematopoietic Stem Cell Transplant Conditioning

Pharmacology Research &Perspectives, Volume 14, Issue 2, April 2026.
ABSTRACT Busulfan is an alkylating agent used in combination with other chemotherapeutic agents and has become a common component of conditioning regimens prior to hematopoietic stem cell transplantation. Busulfan has a very narrow therapeutic index corresponding to the area under the plasma concentration–time curve, with supra‐therapeutic busulfan ...
Colleen Drangines, Janet Laquet, Ranju Kunwor   +2 more
wiley   +1 more source

Sustained Drug-Drug Interaction Between Cyclosporine and Apalutamide in a Patient With Metastatic Hormone-Sensitive Prostate Cancer: A Case Report and Evaluation of CYP3A4 Induction via Pregnane X Receptor Activation by Apalutamide. [PDF]

Case Rep Oncol Med
Mimura Y, Sanda T, Unno R, Furukawa Y, Shizu R, Motokatsu K, Tashiro Y, Tasaki Y, Sugiyama Y, Yasujima T, Naiki T, Horita Y, Hotta Y, Yuasa H, Yoshinari K, Yasui T, Iida S, Furukawa-Hibi Y.   +17 more
europepmc   +1 more source

Amiodarone‐Induced Pulmonary Toxicity With Confirmed Elevated Plasma Mono‐Desethyl‐Amiodarone Levels

Respirology Case Reports, Volume 14, Issue 4, April 2026.
We report a case of pulmonary toxicity that developed 10 months after the initiation of amiodarone. The serum mono‐desethyl‐amiodarone concentration was elevated despite the relatively low cumulative amiodarone dose. ABSTRACT Amiodarone hydrochloride is an effective antiarrhythmic drug that can cause serious adverse effects, including amiodarone ...
Munechika Hara, Miki Kato, Fumika Sugiyama, Ryo Ichikawa, Tsutomu Hachiya   +4 more
wiley   +1 more source

In Silico Comparison of Rifampicin and 25-desacetyl Rifampicin-Induced PXR-Mediated CYP450 Transcriptional Response in 3D Primary Human Hepatocytes. [PDF]

Bull Math Biol
Kahiya ET, Smutný T, Smutná L, Duintjer Tebbens J, Pávek P, Bernhauerová V.   +5 more
europepmc   +1 more source

Cistanche tubulosa Extract Protects Cast Immobilization‐Induced Declines of Muscle Strength and Muscle Mass

Traditional &Kampo Medicine, Volume 13, Issue 1, April 2026.
ABSTRACT Aim One of the effects of Cistanche herb is described in the Chinese Pharmacopoeia as for lack of strength in muscles and bones. However, concrete evidence of this herb for muscle strength has been hardly reported. The present study aimed to clarify the effects of 30% ethanolic extract of Cistanche tubulosa fleshy stem on muscle strength and ...
Jae‐Won Jung, Chihiro Tohda
wiley   +1 more source