Results 191 to 200 of about 61,480 (319)
Stroke is a neurological impairment caused by vascular injury of the central nervous system, and globally, stroke is ranked as the second most common cause of death and disability. Numerous risk factors, disease processes, and mechanisms can contribute to stroke, which is not a single disease. G.
Ali Ikram +6 more
wiley +1 more source
Drug-drug interactions in targeted cancer therapies: a focus on tyrosine kinase inhibitors. [PDF]
Stromatt JC +6 more
europepmc +1 more source
British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 354-356, February 2026.
Jakša Vukojević +3 more
wiley +1 more source
Anticancer Molecular Mechanisms of Curcuminoids: An Updated Review of Clinical Trials
Curcuminoids remain one of the most studied dietary polyphenols as a cancer prevention and treatment agent. Inflammation and tumor progression are related to the NF‐κB signaling pathway, which is also suppressed by curcuminoids. Curcuminoids prevent the activation of a variety of signaling pathways, including the MAPK, PI3K/Akt, and NF‐kB pathways ...
Ushna Momal +14 more
wiley +1 more source
Interaction of cytochrome P450 3A4 with the hydrophilic ligand tetraethylene glycol. [PDF]
Sevrioukova IF.
europepmc +1 more source
Cannabidiol in autism: Clinical pharmacology priorities for trial design
British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 357-359, February 2026.
Gislei Frota Aragão +2 more
wiley +1 more source
Flavonoids derived from Citrus reticulate peel inhibit α‐glucosidase activity, delaying carbohydrate digestion and reducing glucose absorption, thereby indicating their potential as functional food components for type 2 diabetes management. ABSTRACT α‐Glucosidase inhibitors (AGIs) are compounds used to treat type 2 diabetes (T2D) by preventing the ...
Itumeleng T. Baloyi +3 more
wiley +1 more source
Unexpected Clinical Drug-Drug Interaction of Fexinidazole on Midazolam Pharmacokinetics: Insights into Underlying Mechanisms from Clinical Phase I Study Results and Supporting In Vivo/Vitro Evidence. [PDF]
Gassiot M +6 more
europepmc +1 more source
Model Informed Precision Dosing of Tacrolimus in Children Following Heart Transplant
Abstract Tacrolimus is a first‐line immunosuppressant used after solid organ transplantation that suffers from extensive intra‐ and inter‐patient variability and a narrow therapeutic window. Its critical role in a fragile population, coupled with the difficulties identifying and maintaining an appropriate dose within a given patient, make it an ideal ...
Jadon S. Wagstaff +3 more
wiley +1 more source

