Results 121 to 130 of about 25,509 (198)
Effect of Scutellariae Radix Extract on Human CYP450 Mediated-Drug Metabolism
, 2011 − Scutellariae Radix is widely used in the traditional herbal medicine for the treatment of fever, cough, dys-entery, hepatitis and hypertension in Korea, China and Japan.
Sun Young Lim +4 more
core +1 more source
An Unusual Case Report of Iatrogenic Metrorrhagia and Hematochezia Following Itraconazole
Clinical Dermatology ReviewItraconazole is an effective triazole antimycotic drug that has a desirable pharmacokinetic profile to combat various fungal pathogens. It acts by inhibiting ergosterol biosynthesis in fungal cell membranes.
Yashaswi Rai
doaj +1 more source
ChemMedChem, Volume 21, Issue 19, 14 October 2026.A series of diethylene glycol‐linked cyclic derivatives with diversity in the heterocyclic motif have been synthesized and screened for antitumor activity. Two bis‐thiazolo[3,2‐a]pyrimidinone derivatives displayed moderate cytotoxicity, high selectivity against hepatocellular carcinoma cells, promising VEGFR2, and remarkable FGFR2 inhibitory activities
Sami A. Al‐Hussain +6 more
wiley +1 more source
Proteomic consequences of the deletion of cytochrome P450 (CYP450) reductase in mice
, 2021 Microsomal cytochrome P450 (CYP450) reductase enzymes play a major role in drug and xenobiotic metabolism. Mice which are deficient in hepatic CYP450 reductase serve as excellent models in understanding CYP450 drug metabolism and alterations in the ...
Gethings, L.A. +3 more
core
, 2017 VİTAMİN D VE VİTAMİN D METABOLİZMASINDA ROL ALAN CYP450 İZOENZİMLERİNİN HAYVAN MODELİNDE MULTİPL SKLEROZ HASTALIĞININ PATOFİZYOLOJİSİNE ETKİLERİNİN MOLEKÜLER DÜZEYDE ...
Evin, Emre, Adalı, Orhan
core
Soapberry (Sapindus mukorossi Gaertn.) is a tree species of the family Sapindaceae, the pericarp of which is rich in triterpenoid saponins, which are important in chemical production, biomedicine, and other fields.
Zhong Chen +8 more
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PurposeMetabolic syndrome (MetS) is a multifactorial disorder characterized by obesity, insulin resistance, dyslipidemia, hypertension, and chronic inflammation.
Navdha Vyas, Tejal Gandhi
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In vitro evaluation inhibitory effect of piperine on CYP450 activity
This dataset contains the experimental results of the study named "In vitro evaluation of inhibitory effect of piperine on CYP450 activity." This work was developed under the scope of the project CBDHIGHBIO - Strategies to modulate the bioavailability of
Vardanega, Renata, Vicente, António A.
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, 2014 Im Rahmen dieser Bachelorarbeit wurde die CYP450-Genexpression in den drei Hepatozyten-ähnlichen Zellsystemen HepaRGTM, Upcyte® und HepG2 untersucht.
Heiermann, Steffen
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CYP450 Gene Variations and Their Implications for Drug Response: A Pharmacogenomic Review
The Human Genome Project (HGP) has significantly advanced our understanding of how human genetic variation affects drug response, particularly through metabolic enzymes such as Cytochrome P450 (CYP450).
Isti Faiza Sakinah +12 more
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