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Identification and characterization of a tumor necrosis factor receptor like protein encoded by Cyprinid Herpesvirus 2

Developmental & Comparative Immunology, 2021
Virus-encoded tumor necrosis factor receptors (vTNFRs) facilitate viral escape from the host immune response during viral propagation. Cyprinid Herpesvirus-2 (CyHV-2) is a double-stranded DNA virus of alloherpesviridae family that causes great economic losses in the aquaculture industry.
Jian-Fei Lu   +5 more
openaire   +2 more sources

Cyprinid herpesvirus 2 (CyHV-2) ORF67 inhibits IFN expression by competitively obstructing STING phosphorylation.

Fish and Shellfish Immunology
Cyprinid herpesvirus 2 (CyHV-2) caused hematopoietic necrosis in crucian carp (Carassius auratus) has resulted in huge economic losses to the carp aquaculture.
Bao-jie Cui   +9 more
semanticscholar   +1 more source

Establishment and Application of a Rapid Detection Method of Cyprinid Herpesvirus 2 (CyHV-2) in Aquacultural Waters by Using a Novel One-Pot RAA-CRISPR/Cas12a Combined With Fe-Iron Flocculation Technology.

Journal of Fish Diseases
Cyprinid herpesvirus 2 (CyHV-2) poses a substantial global threat to goldfish (Carassius auratus) and crucian carp (Carassius carassius). Despite the development of several sensitive molecular diagnostic techniques, there is an ongoing demand for ...
Zewei Hou   +8 more
semanticscholar   +1 more source

In vitro characteristics of cyprinid herpesvirus 2: effect of kidney extract supplementation on growth

Diseases of Aquatic Organisms, 2015
Herpesviral hematopoietic necrosis caused by goldfish hematopoietic necrosis virus (now identified as cyprinid herpesvirus 2, CyHV-2) has contributed to economic losses in goldfish Carassius auratus culture and is becoming a major obstacle in Prussian carp C. gibelio aquaculture in China.
Tomoya, Shibata   +7 more
openaire   +2 more sources

Evaluation of protective effects of heat-inactivated cyprinid herpesvirus-2 (CyHV-2) vaccine against herpesviral hematopoietic necrosis disease (HVHND) in goldfish (Carassius auratus).

Fish and Shellfish Immunology, 2022
Cyprinid herpesvirus-2 (CyHV-2) is an important virus that causes herpesviral hematopoietic necrosis disease (HVHND) leading to huge economic losses in goldfish (Carassius auratus).
A. Dharmaratnam   +2 more
semanticscholar   +1 more source

Development of a Polymerase Chain Reaction Assay to Detect Cyprinid Herpesvirus 2 in Goldfish

Journal of Aquatic Animal Health, 2009
Abstract Cyprinid herpesvirus 2 (CyHV2) has been associated with epidemic mortality among cultured populations of goldfish Carassius auratus. As the principal target tissues are hematopoietic cells in the kidney and spleen, the disease is designated herpesviral hematopoietic necrosis (HVHN).
Thomas B, Waltzek   +3 more
openaire   +2 more sources

Effect of starvation on the gut microbiota and intestine in gibel carp (Carassius gibelio) against cyprinid herpesvirus-2 (CyHV-2) infection.

Fish and Shellfish Immunology
Viral infections cause substantial economic losses in aquaculture, particularly in intensive aquaculture conditions. While short-term starvation naturally occurs in wild fish and post-infection scenarios, the impact of starvation on gut microbiota and ...
Gao-peng Liu   +4 more
semanticscholar   +1 more source

Immune gene expression and protective effects in goldfish (Carassius auratus L.) immunized with formalin-inactivated cyprinid herpesvirus-2 (CyHV-2) vaccine.

Microbial Pathogenesis, 2022
The goldfish hematopoietic necrosis viral disease (GHNVD) has led to worldwide economic losses in goldfish aquaculture. The present study has focused on the development of an inactivated vaccine for the cyprinid herpesvirus (CyHV-2) and to check the ...
A. Dharmaratnam   +7 more
semanticscholar   +1 more source

Susceptibility of Japanese Cyprininae fish species to cyprinid herpesvirus 2 (CyHV-2)

Veterinary Microbiology, 2014
Cyprinid herpesvirus 2 (CyHV-2) is known as the causative agent of herpesviral haematopoietic necrosis (HVHN) of goldfish (Carassius auratus). Recently, the virus has also been detected from Prussian carp (C. gibelio) and crucian carp (C. carassius) from European and Asian countries.
Takafumi, Ito, Yukio, Maeno
openaire   +2 more sources

Cyprinid Herpesvirus 2 Infection Activates IL-17C/NF-κB/IFNγ Antiviral Signalling Axis in Caudal Fin Cells of Carassius auratus Gibelio.

Journal of Fish Diseases
Crucian carp (Carassius auratus gibelio) is sensitive to the infection of Cyprinid herpesvirus 2 (CyHV-2), displaying severe inflammatory reactions characterised by systemic congestion and gill bleeding.
Yaqing Xie   +3 more
semanticscholar   +1 more source

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