Influence of sex hormones on DNA content and cystathionine-γ-lyase expression in rat myocardium
Zaporožskij Medicinskij Žurnal, 2017 Till now sexual features of cystathionine-γ-lyase/H2S system functioning in heart and its relationship to DNA content in myocardial cells nuclei depending on the level of sex hormones.
A. V. Melnik +4 more
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Enhanced expression of cystathionine β-synthase and cystathionine γ-lyase during acute cholecystitis-induced gallbladder inflammation. [PDF]
PLoS ONE, 2013 BACKGROUND: Hydrogen sulfide (H2S) has recently been shown to play an important role in the digestive system, but the role of endogenous H2S produced locally in the gallbladder is unknown.
Li Zhang +4 more
doaj +2 more sources
A cardioprotective insight of the cystathionine γ-lyase/hydrogen sulfide pathway
International Journal of Cardiology: Heart & Vasculature, 2015 Traditionally, hydrogen sulfide (H2S) was simply considered as a toxic and foul smelling gas, but recently H2S been brought into the spot light of cardiovascular research and development.
Steve Huang, Hua Li, Junbo Ge
doaj +2 more sources
BMC Cancer, 2018 Background Knowledge about the expression and thus a role of enzymes that produce endogenous H2S - cystathionine-β-synthase, cystathionine γ-lyase and mercaptopyruvate sulfurtransferase - in renal tumors is still controversial.
Jan Breza +11 more
doaj +2 more sources
Cystathionine γ-Lyase Self-Inactivates by Polysulfidation during Cystine Metabolism. [PDF]
Int J Mol Sci, 2023 Cystathionine γ-lyase (CSE) is an enzyme responsible for the biosynthesis of cysteine from cystathionine in the final step of the transsulfuration pathway. It also has β-lyase activity toward cystine, generating cysteine persulfide (Cys-SSH).
Araki S +9 more
europepmc +2 more sources
Allosteric activators of cystathionine γ lyase to augment endogenous hydrogen sulfide and inhibit pathologic calcification [PDF]
Pharmacological ResearchHydrogen sulfide (H₂S), a gasotransmitter naturally produced in the body by enzymes such as cystathionine γ lyase (CSE), helps reduce inflammation, oxidative stress, and abnormal tissue calcification.
Sonia Nasi +11 more
doaj +2 more sources
Cystathionine γ-lyase S-sulfhydrates SIRT1 to attenuate myocardial death in isoprenaline-induced heart failure. [PDF]
Redox Rep, 2023 Objective: Hydrogen sulfide (H2S), the third gasotransmitter, plays a critical role in protecting against heart failure. Sirtuin-1 (SIRT1) is a highly conserved histone deacetylase that has a protective role in the treatment of heart failure by ...
Wu D, Sun Y, Gu Y, Zhu D.
europepmc +2 more sources
Purification and characterization of cystathionine γ-lyase fromLactobacillus fermentumDT41 [PDF]
FEMS Microbiology Letters, 1998 A homo-tetrameric ca. 140-kDa cystathionine gamma-lyase was purified to homogeneity from Lactobacillus fermentum DT41 by four chromatographic steps. This was the first enzyme responsible for amino acid catabolism purified from lactobacilli. The activity is pyridoxal-5'-phosphate dependent and the enzyme catalyzes the alpha,gamma-elimination reaction of
E, Smacchi, M, Gobbetti
openaire +2 more sources
β3 Relaxant Effect in Human Bladder Involves Cystathionine γ-Lyase-Derived Urothelial Hydrogen Sulfide. [PDF]
Antioxidants (Basel), 2022 It is now well established that the urothelium does not act as a passive barrier but contributes to bladder homeostasis by releasing several signaling molecules in response to physiological and chemical stimuli.
Mitidieri E +13 more
europepmc +2 more sources
Global Survey, Expressions and Association Analysis of CBLL Genes in Peanut
Frontiers in Genetics, 2022 Cystathionine γ-synthase (CGS), methionine γ-lyase (MGL), cystathionine β-lyase (CBL) and cystathionine γ-lyase (CGL) share the Cys_Met_Meta_PP domain and play important roles in plant stress response and development.
Weifang Ren +15 more
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