Results 41 to 50 of about 412,162 (161)

HOAs are present in diverse fungal pathogens but absent in their gramineous hosts.

, 2023
The heat map shows the gene number of the key enzymes in the biosynthesis of methionine in fungi and plants examined. CBL, cystathionine β-lyase. CBS, cystathionine β-synthase. CGL, cystathionine γ-lyase. CGS, cystathionine γ-synthase.
Leiyun Yang (2636971), Zhengguang Zhang (190550), Jun Zhang (48506), Xinyu Liu (34266), Zhuoer Xie (7289042), Haifeng Zhang (137541), Ping Wang (42415), Han Chen (228557), Muxing Liu (716957), Huimin Li (126429), Pengcheng Mo (17020969)   +10 more
core   +1 more source

YALI0C22088g from Yarrowia lipolytica catalyses the conversion of l‐methionine into volatile organic sulfur‐containing compounds

Microbial Biotechnology, 2021
Summary The enzymatic conversion of l‐methionine (l‐Met) into volatile organic sulfur‐containing compounds (VOSCs) plays an important role in developing the characteristic aroma of foods.
Quan‐Lu Zhao, Zhu‐Lin Wang, Lan Yang, Sai Zhang, Kai‐Zhi Jia   +4 more
doaj   +1 more source

Hydrogen Sulfide Attenuates Lymphedema Via the Induction of Lymphangiogenesis Through a PI3K/Akt‐Dependent Mechanism

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Accumulating evidence suggests that hydrogen sulfide ( H2S ), an endogenously produced gaseous molecule, plays a critical role in the regulation of cardiovascular homeostasis. However, little is known about its role in lymphangiogenesis. Thus,
Junya Suzuki, Yuuki Shimizu, Takumi Hayashi, Yiyang Che, Zhongyue Pu, Kazuhito Tsuzuki, Shingo Narita, Rei Shibata, Isao Ishii, John W. Calvert, Toyoaki Murohara   +10 more
doaj   +1 more source

Hydrogen Sulfide Levels and Nuclear Factor‐Erythroid 2‐Related Factor 2 (NRF2) Activity Are Attenuated in the Setting of Critical Limb Ischemia (CLI)

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2015
Background Cystathionine γ‐lyase, cystathionine β‐synthase, and 3‐mercaptopyruvate sulfurtransferase are endogenous enzymatic sources of hydrogen sulfide (H2S).
Kazi N. Islam, David J. Polhemus, Erminia Donnarumma, Luke P. Brewster, David J. Lefer   +4 more
doaj   +1 more source

Chronic aspartame intake causes changes in the trans-sulphuration pathway, glutathione depletion and liver damage in mice

Redox Biology, 2017
No-caloric sweeteners, such as aspartame, are widely used in various food and beverages to prevent the increasing rates of obesity and diabetes mellitus, acting as tools in helping control caloric intake.
Isabela Finamor, Salvador Pérez, Caroline A. Bressan, Carlos E. Brenner, Sergio Rius-Pérez, Patricia C. Brittes, Gabriele Cheiran, Maria I. Rocha, Marcelo da Veiga, Juan Sastre, Maria A. Pavanato   +10 more
doaj   +1 more source

Influence of polymicroelement preparation Esmin on hydrogen sulfide levels and indices of pro- and antioxidant system in the rat myocardium of different age [PDF]

The Ukrainian Biochemical Journal, 2014
The influence of microelement preparation Esmin on hydrogen sulfide (H2S) levels, activity of H2S -producing enzymes and indices of pro-/antioxidant system in the myocardium of different age rats were investigated.
N. V. Zaichko, A. S. Olhovskiy, A. V. Melnik, P. A. Yurchenko, A. S. Grigorieva, N. F. Konahovich   +5 more
doaj   +1 more source

Fragment-based de novo design of a cystathionine γ-lyase selective inhibitor blocking hydrogen sulfide production [PDF]

, 2016
Hydrogen sulfide is an essential catabolite that intervenes in the pathophysiol. of several diseases from hypertension to stroke, diabetes and pancreatitis.
Caliendo Giuseppe, CORVINO, ANGELA, Bucci Mariarosaria, CALIENDO, GIUSEPPE, Kelly, Geoff, Kelly Geoff, Pastore Annalisa, Magli Elisa, Servillo, Luigi, Popowicz, Grzegorz, Servillo Luigi, Popowicz Grzegorz, BUCCI, MARIAROSARIA, Corvino Angela, Pastore, Annalisa; id_orcid, Perissutti Elisa, PERISSUTTI, ELISA, CIRINO, GIUSEPPE, MAGLI, ELISA, FRECENTESE, FRANCESCO, Frecentese Francesco, SEVERINO, BEATRICE, Severino Beatrice, Fiorino Ferdinando, Cirino Giuseppe, Santagada Vincenzo, FIORINO, FERDINANDO, SANTAGADA, VINCENZO, Pastore, Annalisa   +28 more
core   +1 more source

Hydrogen Sulfide Deficiency and Therapeutic Targeting in Cardiometabolic HFpEF

JACC: Basic to Translational Science
Summary: Heart failure with preserved ejection fraction (HFpEF) presents significant treatment challenges. We assessed hydrogen sulfide (H2S) bioavailability in HFpEF patients and 2 animal models: the ''2-hit'' L-NAME + high-fat diet mouse model and ZSF1
Jake E. Doiron, PhD, Mahmoud H. Elbatreek, PhD, Huijing Xia, PhD, Xiaoman Yu, MS, Natalie D. Gehred, BA, Tatiana Gromova, BS, Jingshu Chen, PhD, Ian H. Driver, PhD, Naoto Muraoka, PhD, Martin Jensen, PhD, Smitha Shambhu, MS, W.H. Wilson Tang, MD, Kyle B. LaPenna, PhD, Thomas E. Sharp, III, PhD, Traci T. Goodchild, PhD, Ming Xian, PhD, Shi Xu, PhD, Heather Quiriarte, MS, Timothy D. Allerton, PhD, Alexia Zagouras, MD, MS, Jennifer Wilcox, BS, Sanjiv J. Shah, MD, Josef Pfeilschifter, PhD, Karl-Friedrich Beck, PhD, Thomas M. Vondriska, PhD, Zhen Li, PhD, David J. Lefer, PhD   +26 more
doaj   +1 more source

Glutathione depletion causes a JNK and p38MAPK-mediated increase in expression of cystathionine-gamma-lyase and upregulation of the transsulfuration pathway in C6 glioma cells [PDF]

, 2015
Cancer cells have a high demand for cysteine as precursor of the antioxidant, glutathione, that is required to promote cell growth and division. Uptake of cystine by the View the MathML source cystine-glutamate exchanger provides the majority of cysteine,
McBean, Gethin J., Kandil, Sarah, Brennan, Lorraine   +2 more
core   +1 more source

Harnessing Methylselenol (CH3SeH): A Highly Effective Platform for Stimuli‐Responsive Delivery With Therapeutic Potential

Advanced Science, EarlyView.
Tools for controlled selenol delivery are crucial for exploring Se‐related biology and medicine, but compound platforms for triggerable release of CH3SeH remain lacking. Herein, we report the first general triggered platform (TD‐MSe) for efficient cyclization release of CH3SeH in live cells.
Wenfang Liang, Liyue Wang, Xuan Wang, Xinran Li, Hao Xing, Lu Sun, Zhen Xi, Long Yi   +7 more
wiley   +1 more source