Results 61 to 70 of about 10,826 (180)

The therapeutic potential for targeting CSE/H2S signaling in macrophages against Escherichia coli infection

Veterinary Research, 2023
Macrophages play a pivotal role in the inflammatory response to the zoonotic pathogen E. coli, responsible for causing enteric infections. While considerable research has been conducted to comprehend the pathogenesis of this disease, scant attention ...
Shaodong Fu, Zhenglei Wang, Xiangan Han, Yuanyuan Xu, Jinfeng Miao   +4 more
doaj   +1 more source

LC-MS proteomics analysis of the iInsulin/IGF-1-deficient Caenorhabditis elegans daf-2(e1370) mutant reveals extensive restructuring of intermediary metabolism [PDF]

, 2014
The insulin/IGF-1 receptor is a major known determinant of dauer formation, stress resistance, longevity, and metabolism in Caenorhabditis elegans. In the past, whole-genome transcript profiling was used extensively to study differential gene expression ...
Braeckman, Bart, Brewer, Heather M, Camp, David G, II, Depuydt, Geert, Petyuk, Vladislav A, Smith, Richard D, Smolders, Arne, Xie, Fang   +7 more
core   +2 more sources

YALI0C22088g from Yarrowia lipolytica catalyses the conversion of l‐methionine into volatile organic sulfur‐containing compounds

Microbial Biotechnology, 2021
Summary The enzymatic conversion of l‐methionine (l‐Met) into volatile organic sulfur‐containing compounds (VOSCs) plays an important role in developing the characteristic aroma of foods.
Quan‐Lu Zhao, Zhu‐Lin Wang, Lan Yang, Sai Zhang, Kai‐Zhi Jia   +4 more
doaj   +1 more source

Hydrogen Sulfide Mitigates Myocardial Infarction via Promotion of Mitochondrial Biogenesis-Dependent M2 Polarization of Macrophages. [PDF]

, 2016
Published onlineJOURNAL ARTICLEAIMS: Macrophages are of key importance for tissue repair after myocardial infarction (MI). Hydrogen sulfide (H2S) has been shown to exert cardioprotective effects in MI.
Miao, L, Moore, PK, Shen, X, Shen, Y, Whiteman, M, Xin, H, Xin, X, Zhu, Y   +7 more
core   +1 more source

Tanshinone IIA Stimulates Cystathionine γ-Lyase Expression and Protects Endothelial Cells from Oxidative Injury

Antioxidants, 2021
Tanshinone IIA (Tan IIA), an active ingredient of Danshen, is a well-used drug to treat cardiovascular diseases. Currently, the mechanisms involved remain poorly understood.
Qiaojing Yan, Zhi-min Mao, Jingru Hong, Kun Gao, M. Niimi, T. Mitsui, Jian Yao   +6 more
semanticscholar   +1 more source

Zofenopril Protects Against Myocardial Ischemia–Reperfusion Injury by Increasing Nitric Oxide and Hydrogen Sulfide Bioavailability

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundZofenopril, a sulfhydrylated angiotensin‐converting enzyme inhibitor (ACEI), reduces mortality and morbidity in infarcted patients to a greater extent than do other ACEIs.
Erminia Donnarumma, Murtuza J. Ali, Amanda M. Rushing, Amy L. Scarborough, Jessica M. Bradley, Chelsea L. Organ, Kazi N. Islam, David J. Polhemus, Stefano Evangelista, Giuseppe Cirino, J. Stephen Jenkins, Rajan A. G. Patel, David J. Lefer, Traci T. Goodchild   +13 more
doaj   +1 more source

A critical role for cystathionine-β-synthase in hydrogen sulfide-mediated hypoxic relaxation of the coronary artery [PDF]

, 2017
Hypoxia-induced coronary artery vasodilatation protects the heart by increasing blood flow under ischemic conditions, however its mechanism is not fully elucidated.
Alexander, Stephen P.H., Donovan, J., Dunn, William R., Garle, M.J., Ralevic, Vera, Roberts, Richard E., Wong, P.S.   +6 more
core   +2 more sources

Роль системи Н2S / цистатіонін-γ-ліаза в механізмах кардіопротекторної дії вітаміну D за дієт-індукованого ожиріння [PDF]

, 2023
Obesity and vitamin D deficiency are risk factors for cardiovascular disease that are often coexisting. The identification of new biochemical factors that may modify the cardiovascular effects of vitamin D in obesity remains relevant.
Заічко, Н. В., Остренюк, Р. С.   +1 more
core   +1 more source

Hydrogen Sulfide Levels and Nuclear Factor‐Erythroid 2‐Related Factor 2 (NRF2) Activity Are Attenuated in the Setting of Critical Limb Ischemia (CLI)

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2015
Background Cystathionine γ‐lyase, cystathionine β‐synthase, and 3‐mercaptopyruvate sulfurtransferase are endogenous enzymatic sources of hydrogen sulfide (H2S).
Kazi N. Islam, David J. Polhemus, Erminia Donnarumma, Luke P. Brewster, David J. Lefer   +4 more
doaj   +1 more source

Chronic aspartame intake causes changes in the trans-sulphuration pathway, glutathione depletion and liver damage in mice

Redox Biology, 2017
No-caloric sweeteners, such as aspartame, are widely used in various food and beverages to prevent the increasing rates of obesity and diabetes mellitus, acting as tools in helping control caloric intake.
Isabela Finamor, Salvador Pérez, Caroline A. Bressan, Carlos E. Brenner, Sergio Rius-Pérez, Patricia C. Brittes, Gabriele Cheiran, Maria I. Rocha, Marcelo da Veiga, Juan Sastre, Maria A. Pavanato   +10 more
doaj   +1 more source