Results 81 to 90 of about 12,014 (181)

EDHF: An update [PDF]

, 2009
The endothelium controls vascular tone not only by releasing NO and prostacyclin, but also by other pathways causing hyperpolarization of the underlying smooth muscle cells.
Félétou, M, VanHoutte, PM
core   +1 more source

LCN2‐ACOD1 Signalling Affects the Post‐Injury Regeneration of Skeletal Muscle Through Mediating Ferroptosis

Cell Proliferation, EarlyView.
LCN2 mediates the suppression of C2C12 myoblast proliferation and myotube formation via erastin‐induced ferroptosis. Mechanistically, the LCN2‐ACOD1 axis regulates skeletal muscle growth via mitochondria‐associated ferroptosis, providing a theoretical basis for the prevention and therapy of muscle‐related diseases.
Xiaojing Hao, Hongwei Shi, Di Wu, Rui Liang, Tong Zhao, Wen Sun, Yue Wang, Xiuju Yu, Xiaomao Luo, Yi Yan, Jiayin Lu, Haidong Wang, Juan Wang   +12 more
wiley   +1 more source

Hydrogen sulfide metabolism regulates endothelial solute barrier function

Redox Biology, 2016
Hydrogen sulfide (H2S) is an important gaseous signaling molecule in the cardiovascular system. In addition to free H2S, H2S can be oxidized to polysulfide which can be biologically active.
Shuai Yuan, Sibile Pardue, Xinggui Shen, J. Steven Alexander, A. Wayne Orr, Christopher G. Kevil   +5 more
doaj   +1 more source

Endothelial Cell Cystathionine γ‐Lyase Expression Level Modulates Exercise Capacity, Vascular Function, and Myocardial Ischemia Reperfusion Injury

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2020
Background Hydrogen sulfide (H2S) is an important endogenous physiological signaling molecule and exerts protective properties in the cardiovascular system.
Huijing Xia, Zhen Li, Thomas E. Sharp, David J. Polhemus, J. Carnal, Karl Moles, Y. Tao, J. Elrod, J. Pfeilschifter, K. Beck, D. Lefer   +10 more
semanticscholar   +1 more source

Longitudinal metabolomics study of phosphate‐adenine‐guanosine‐glucose‐saline‐mannitol stored red blood cells

Transfusion, EarlyView.
Abstract Background The storage of red blood cells (RBCs) is essential for transfusion but leads to storage lesions that compromise RBC quality and increase the risk of transfusion‐related adverse effects, including allergic transfusion reactions (ATRs). Understanding storage‐induced metabolic change is crucial for enhancing transfusion safety.
Gürkan Bal, Maia Dzamashvili, Zhuoran Li, Magda Babina, Nidal Toman, Abdulgabar Salama   +5 more
wiley   +1 more source

Improving the nutritive value of rice seeds: elevation of cysteine and methionine contents in rice plants by ectopic expression of a bacterial serine acetyltransferase

, 2012
With the aim of increasing the cysteine level in rice (Oryza sativa L.) and thus improving its nutritional quality, transgenic rice plants were generated expressing an Escherichia coli serine acetyltransferase isoform (EcSAT), the enzyme synthesizing O ...
Hesse, H., Hoefgen, R., Nguyen, H.
core   +1 more source

A critical role for cystathionine-β-synthase in hydrogen sulfide-mediated hypoxic relaxation of the coronary artery [PDF]

, 2017
Hypoxia-induced coronary artery vasodilatation protects the heart by increasing blood flow under ischemic conditions, however its mechanism is not fully elucidated.
Alexander, Stephen P.H., Donovan, J., Dunn, William R., Garle, M.J., Ralevic, Vera, Roberts, Richard E., Wong, P.S.   +6 more
core   +2 more sources

Sodium thiosulfate treatment rescues hyperglycaemia‐induced pronephros damage in zebrafish by upregulating nitric oxide signalling

The Journal of Physiology, EarlyView.
Abstract figure legend Sodium thiosulfate (STS) rescues the pronephros phenotype of pdx1 morphants through compensatory upregulation of nitric oxide (NO) metabolism. Zebrafish larvae injected with a control morpholino show the typical pronephros structure at 48 h post‐fertilization (hpf) with and without STS treatment.
Hannes Ott, Katrin Bennewitz, Xin Zhang, Mariia Prianichnikova, Carsten Sticht, Gernot Poschet, Jens Kroll   +6 more
wiley   +1 more source

Hydrogen sulfide regulates insulin secretion and insulin resistance in diabetes mellitus, a new promising target for diabetes mellitus treatment? A review

Journal of Advanced Research, 2021
Background: Insulin resistance and impaired insulin secretion lead to disorders of glucose metabolism, which contributes to the development of diabetes.
Heng Zhang, Yaqian Huang, Selena Chen, Chaoshu Tang, Guang Wang, Junbao Du, Hongfang Jin   +6 more
doaj   +1 more source

The role of H2S bioavailability in endothelial dysfunction [PDF]

, 2016
This is the author accepted manuscript. The final version is available from the publisher via the DOI in this record.Endothelial dysfunction (EDF) reflects pathophysiological changes in the phenotype and functions of endothelial cells that result from ...
Ahmed, A, Ichinose, F, Papapetropoulos, A, Szabo, C, Wang, R, Whiteman, M   +5 more
core   +1 more source