Results 101 to 110 of about 555,922 (178)

Identification of probasin-related antigen as cystathionine gamma-lyase by molecular cloning.

Journal of Biological Chemistry, 1994
We reported previously that a monoclonal antibody against probasin (rat prostatic secretory protein) recognizes a 40-kDa protein localized in rat liver and kidney. The protein (probasin-related antigen, PRB-RA) may participate in a specific differentiated function of these tissues.
N, Nishi, H, Tanabe, H, Oya, M, Urushihara, H, Miyanaka, F, Wada   +5 more
openaire   +2 more sources

CYSTATHIONINE GAMMA–LYASE AS A REGULATOR OF RESISTANCE ARTERY CONTRACTION UNDER NORMAL AND HYPERGLYCEMIC CONDITIONS [PDF]

, 2013
The aim of our study is to clarify the contribution of cystathionine gamma–lyase (CSE) that produces H2S in smooth muscleand perivascular adipose tissues in the regulation of resistance size rat artery contraction.
Daneva , T., S. Gagov , H., Dimitrova , D., Emilova , R., Georgiev , V.   +4 more
core  

Persulfidation of Human Cystathionine γ-Lyase Inhibits Its Activity: A Negative Feedback Regulation Mechanism for H2S Production

Cystathionine γ-lyase (CSE) is the second enzyme in the trans-sulfuration pathway that converts cystathionine to cysteine. It is also one of three major enzymes responsible for the biosynthesis of hydrogen sulfide (H2S).
Guanya Jia, Heng Li, Jun Wang, Haisheng Gan, Yongyi Ye, Xiaoya Shang, Weining Niu, Yanxiong Wang, Zhilong Zhu   +8 more
core   +1 more source

Allosteric activators of cystathionine γ lyase to augment endogenous hydrogen sulfide and inhibit pathologic calcification

Pharmacological Research
Hydrogen sulfide (H₂S), a gasotransmitter naturally produced in the body by enzymes such as cystathionine γ lyase (CSE), helps reduce inflammation, oxidative stress, and abnormal tissue calcification.
Sonia Nasi, Driss Ehirchiou, Cindy Blatter, Veronique Chobaz, Stefan Germann, Alexandra Brandenberger, Elias Bommeli, Emiko Uchikawa, Giuseppe Cirino, Rainer Riedl, Alexander So, Nathalie Busso   +11 more
doaj   +1 more source

The Supersulfide-Producing Activity of Rat Cystathionine γ-Lyase Is Irreversibly Inactivated by L-CysNO but Not by L-GSNO

Cystathionine γ-lyase (CSE) is a pyridoxal 5′-phosphate (PLP)-dependent enzyme that catalyzes the final step of the transsulfuration pathway, converting cystathionine into cysteine.
Yasuo Watanabe, Takaaki Akaike, Shingo Kasamatsu, Sunghyeon Yoon, Shoma Araki, Tsuyoshi Takata, Yukihiro Tsuchiya, Hidehiko Nakagawa, Hideshi Ihara   +8 more
core   +1 more source

Hydrogen sulfide and its role in female reproduction

Frontiers in Veterinary Science
Hydrogen sulfide (H2S) is a gaseous signaling molecule produced in the body by three enzymes: cystathionine-β-synthase (CBS), cystathionine-γ-lyase (CSE) and 3-mercaptopyruvate sulfurtransferase (3-MST).
Aneta Pilsova, Zuzana Pilsova, Barbora Klusackova, Natalie Zelenkova, Eva Chmelikova, Pavla Postlerova, Marketa Sedmikova   +6 more
doaj   +1 more source

Exogenous H2S Regulates of Cystathionine Gamma-Lyase in HUVECs During Hypoxia

, 2020
Cystathionine gamma-lyase (CSE) is one of the essential H2S-producing enzymes, and it regulates diverse functions in connection with cardiovascular function. It is crucial how exogenous H2S regulates CSE expression of the vascular endothelial cell during hypoxia.
openaire   +2 more sources

Differential Roles of Cystathionine Gamma-Lyase and Mercaptopyruvate Sulfurtransferase in Hapten-Induced Colitis and Contact Dermatitis in Mice. [PDF]

Int J Mol Sci, 2023
Akahoshi N, Hasegawa R, Yamamoto S, Takemoto R, Yoshizawa T, Kamichatani W, Ishii I.   +6 more
europepmc   +1 more source

Exogenous H2S Regulates the Expression of Cystathionine Gamma-Lyase In HUVECs During Hypoxia

, 2021
Cystathionine gamma-lyase (CSE) is one of the essential H2S-producing enzymes, and it regulates diverse functions in connection with cardiovascular function. It is crucial how exogenous H2S regulates CSE expression of the vascular endothelial cell during hypoxia.
openaire  

Cystathionine γ Lyase Sulfhydrates the RNA Binding Protein Human Antigen R to Preserve Endothelial Cell Function and Delay Atherogenesis [PDF]

, 2019
Hydrogen sulfide (H2S), generated by cystathionine γ lyase (CSE), is an important endogenous regulator of vascular function. The aim of the present study was to investigate the control and consequences of CSE activity in endothelial cells under ...
Siuda, Daniel, Szabo, Csaba, Papapetropoulos, Andreas, Sigala, Fragiska, Randriamboavonjy, Voahanginirina, Fleming, Ingrid, Malik, Randa Abdel, Heidler, Juliana, Siragusa, Mauro, Zukunft, Sven, Luck, Bert, Wang, Dao Wen, Hu, Jiong, Chen, Chen, Wittig, Ilka, Filis, Konstantinos A., Schürmann, Christoph, Zografos, George, Wittig, Janina, Kojonazarov, Baktybek, Bibli, Sofia-Iris, Pfeilschifter, Josef, Tsilimigras, Diamantis I., Brandes, Ralf P.   +23 more
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