Results 31 to 40 of about 1,391 (117)
H$_{2}$S, polysulfides, and enzymes : physiological and pathological aspec [PDF]
, 2020 We have been studying the general aspects of the functions of H$_{2}$S and polysulfides, and the enzymes involved in their biosynthesis, for more than 20 years.
Noriyuki Nagahara
core +1 more source
Nitric oxide and hydrogen sulfide: the gasotransmitter paradigm of the vascular system. [PDF]
, 2017 There are several reviews on NO and hydrogen sulfide (H2 S) and their role in vascular diseases in the current relevant literature. The aim of this review is to discuss, within the limits of present knowledge, the interconnection between these two ...
Bucci, M., Cirino, G, Vellecco, V
core +1 more source
Macromolecular Materials and Engineering, Volume 311, Issue 2, February 2026.This study develops N‐acetylcysteine‐loaded polycaprolactone fibers for cartilage regeneration to investigate their potential in regulating redox balance. The fibers exhibit antioxidant properties and modulate genes related to glutathione and transsulfuration pathways.
Kubra Yigit, Anthony Callanan
wiley +1 more source
Lifespan‐Extending Endogenous Metabolites
Aging Cell, Volume 25, Issue 2, February 2026.Endogenous metabolites act as mediators of longevity by modulating conserved cellular pathways. We summarize mechanistic evidence linking specific metabolites to lifespan and healthspan benefits across model systems, with discussion of clinical evidence, translational opportunities, and remaining knowledge gaps.
Yizhou Jiang, Jing‐Dong J. Han
wiley +1 more source
Activation of the eIF2α/ATF4 axis drives triple-negative breast cancer radioresistance by promoting glutathione biosynthesis. [PDF]
, 2022 Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype. Radiotherapy is an effective option for the treatment of TNBC; however, acquired radioresistance is a major challenge to the modality.
Bai, X +7 more
core +1 more source
Food Science &Nutrition, Volume 14, Issue 1, January 2026.The modified calycosin derivative H10 was more effective in inhibiting cell proliferation through G0/G1 cell cycle arrest, together with inhibiting the migration and colony formation abilities of ovarian cancer cell lines SKOV3 and A2780. Comparative proteomic analysis coupled with Ingenuity Pathway Analysis further delineated calycosin derivative H10 ...
Fuhong Yang +8 more
wiley +1 more source
Inhibition of endogenous hydrogen sulfide production reduces activation of hepatic stellate cells via the induction of cellular senescence. [PDF]
Cell CycleIn chronic liver injury, quiescent hepatic stellate cells (HSCs) transdifferentiate into activated myofibroblast-like cells and produce large amounts of extracellular matrix components, e.g. collagen type 1.
Damba T +9 more
europepmc +5 more sources
Egyptian Journal of Medical Human GeneticsBackground Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer globally, with high morbidity and mortality due to late-stage diagnoses, treatment resistance, and recurrence. Hydrogen sulfide (H2S) metabolism, primarily regulated
Mohamed Rizwan Ghouse +3 more
doaj +1 more source
Hydrogen sulfide formation in experimental model of acute pancreatitis [PDF]
, 2019 Acute pancreatitis (AP) is a disease defined as acute or chronic inflammatory process of the pancreas characterized by premature activation of digestive enzymes within the pancreatic acinar cells and causing pancreatic auto-digestion.
Bronowicka-Adamska, Patrycja +4 more
core +1 more source
The role of the gaseous signaling molecule hydrogen sulfide in chronic liver disease:Special emphasis on non-alcoholic fatty liver disease [PDF]
, 2020 Due to the high world-wide prevalence of obesity, non-alcoholic fatty liver disease (NAFLD) has become one of the major chronic liver diseases in the world.
Damba, Turtushikh
core +2 more sources